Role of the LAT adaptor in T-cell development and Th2 differentiation (Q36231103)

12 August 2017

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title

Role of the LAT adaptor in T-cell development and Th2 differentiation (English)

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12 August 2017

Enrique Aguado

2

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Marie Malissen

object named as

Marie Malissen

series ordinal

3

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Bernard Malissen

object named as

Bernard Malissen

series ordinal

1

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publication date

1 January 2005

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12 August 2017

Advances in Immunology

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12 August 2017

87

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12 August 2017

1-25

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Induction of T helper type 2 immunity by a point mutation in the LAT adaptor

12 August 2017

1 reference

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7 January 2021

CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Natively unfolded domains in endocytosis: hooks, lines and linkers.

1 reference

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7 January 2021

T cell receptor specificity is critical for the development of epidermal gammadelta T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

T helper cell differentiation: on again, off again

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Synergistic assembly of linker for activation of T cells signaling protein complexes in T cell plasma membrane domains

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Transcription: tantalizing times for T cells

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Binding specificity of multiprotein signaling complexes is determined by both cooperative interactions and affinity preferences

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Linker for activation of B cells: a functional equivalent of a mutant linker for activation of T cells deficient in phospholipase C-gamma1 binding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

LAB: a new membrane-associated adaptor molecule in B cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Adaptors as central mediators of signal transduction in immune cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Role of TCR-induced extracellular signal-regulated kinase activation in the regulation of early IL-4 expression in naive CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Transmembrane adapters: structure, biochemistry and biology

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Progressive differentiation and selection of the fittest in the immune response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

T cell development in TCR beta enhancer-deleted mice: implications for alpha beta T cell lineage commitment and differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Identification of the minimal tyrosine residues required for linker for activation of T cell function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

The single positive T cells found in CD3-zeta/eta-/- mice overtly react with self-major histocompatibility complex molecules upon restoration of normal surface density of T cell receptor-CD3 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Function of the CD3 subunits of the pre-TCR and TCR complexes during T cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Negative feedback loop in T-cell activation through MAPK-catalyzed threonine phosphorylation of LAT.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

The lineage decisions of helper T cells

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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

LAT regulates gammadelta T cell homeostasis and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Appearance of the LAT protein at an early stage of B-cell development and its possible role

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Intrathymic delta selection events in gammadelta cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Ontogenic development and tissue distribution of V gamma 1-expressing gamma/delta T lymphocytes in normal mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Autosomal recessive hyperimmunoglobulin E syndrome: a distinct disease entity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

CD28, Ox-40, LFA-1, and CD4 modulation of Th1/Th2 differentiation is directly dependent on the dose of antigen.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

A LAT mutation that inhibits T cell development yet induces lymphoproliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

LAT links the pre-BCR to calcium signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Dynamic changes in the mobility of LAT in aggregated lipid rafts upon T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Innate and adaptive immunity: specificities and signaling hierarchies revisited

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Thymic selection revisited: how essential is it?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Signaling life and death in the thymus: timing is everything

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Unexpectedly late expression of intracellular CD3epsilon and TCR gammadelta proteins during adult thymus development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Essential role of LAT in T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

Cutting Edge: Localization of linker for activation of T cells to lipid rafts is not essential in T cell activation and development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4

7 January 2021

10.1016/S0065-2776(05)87001-4

Identifiers

DOI

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12 August 2017

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PubMed ID

16102570