TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts (Q36245735)

13 August 2017

TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts (English)

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13 August 2017

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Alison M Connor

1

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13 August 2017

Nizar Mahomed

2

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13 August 2017

Rajiv Gandhi

3

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13 August 2017

Edward C Keystone

4

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13 August 2017

Stuart A Berger

5

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13 August 2017

14 March 2012

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Arthritis Research and Therapy

13 August 2017

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13 August 2017

14

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13 August 2017

R62

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13 August 2017

2

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describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3446430/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/ar3778

0 references

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TNF-alpha induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress

1 October 2017

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1 October 2017

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Inhibition of lysosomal functions reduces proteasomal activity

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factor-alpha-induced cell death in MCF-7 cells

1 October 2017

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1 October 2017

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Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus

1 October 2017

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Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

1 October 2017

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How to interpret LC3 immunoblotting

1 October 2017

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

1 October 2017

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Proteasome function is regulated by cyclic AMP-dependent protein kinase through phosphorylation of Rpt6

1 October 2017

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Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects

1 October 2017

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1 October 2017

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1 October 2017

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NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy

1 October 2017

1 reference

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Resistance to endoplasmic reticulum stress is an acquired cellular characteristic of rheumatoid synovial cells

1 October 2017

1 reference

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Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts

1 October 2017

1 reference

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Endogenous MHC class II processing of a viral nuclear antigen after autophagy.

1 October 2017

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Disturbed cholesterol traffic but normal proteolytic function in LAMP-1/LAMP-2 double-deficient fibroblasts

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

1 October 2017

1 reference

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Autophagosome formation in mammalian cells

1 October 2017

1 reference

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Apoptosis as a therapeutic tool in rheumatoid arthritis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

1 October 2017

1 reference

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Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

1 October 2017

1 reference

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Role of the proteasome and NF-kappaB in streptococcal cell wall-induced polyarthritis

1 October 2017

1 reference

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The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

Protein degradation in cultured cells. II. The uptake of chloroquine by rat fibroblasts and the inhibition of cellular protein degradation and cathepsin B1.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

Tunicamycin inhibition of polyisoprenyl N-acetylglucosaminyl pyrophosphate formation in calf-liver microsomes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

Regulation of apoptosis by the unfolded protein response.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

Bioavailability of hydroxychloroquine tablets in patients with rheumatoid arthritis

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

Attenuation of pain and inflammation in adjuvant-induced arthritis by the proteasome inhibitor MG132.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

Processing of autophagic protein LC3 by the 20S proteasome

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

Cell-based bioluminescent assays for all three proteasome activities in a homogeneous format.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

The proinflammatory cytokines IL-1beta and TNF-alpha induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446430

Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22417670

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/AR3778

1 reference

13 August 2017

1 reference

13 August 2017

1 reference