Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival (Q36284095)

13 August 2017

Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival (English)

1 reference

13 August 2017

0 references

Jonathan M Haldeman

3

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Samuel B Stephens

object named as

Samuel B Stephens

6

0 references

Christopher B Newgard

4

object named as

Christopher B Newgard

1 reference

13 August 2017

Heather L Hayes

1

1 reference

13 August 2017

Brett S Peterson

2

1 reference

13 August 2017

Hans E Hohmeier

5

1 reference

13 August 2017

language of work or name

English

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publication date

17 February 2017

1 reference

13 August 2017

1 reference

13 August 2017

12

1 reference

13 August 2017

e0172567

1 reference

13 August 2017

2

1 reference

Creative Commons Attribution 4.0 International

13 August 2017

start time

17 February 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity

30 September 2017

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The diabetes susceptibility gene Clec16a regulates mitophagy

30 September 2017

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Multi-parameter single-cell kinetic analysis reveals multiple modes of cell death in primary pancreatic β-cells.

30 September 2017

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Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion.

30 September 2017

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30 September 2017

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Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes

30 September 2017

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30 September 2017

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Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death

30 September 2017

1 reference

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A VGF-derived peptide attenuates development of type 2 diabetes via enhancement of islet β-cell survival and function.

30 September 2017

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Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets

30 September 2017

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Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic β-cells

30 September 2017

1 reference

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A human islet cell culture system for high-throughput screening

30 September 2017

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Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice

30 September 2017

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Contamination with E1A-positive wild-type adenovirus accounts for species-specific stimulation of islet cell proliferation by CCK: a cautionary note.

30 September 2017

1 reference

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Adaptive beta-cell proliferation is severely restricted with advanced age.

30 September 2017

1 reference

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Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice

30 September 2017

1 reference

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Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1

30 September 2017

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Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes

30 September 2017

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Chromatin modification of Apaf-1 restricts the apoptotic pathway in mature neurons

30 September 2017

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Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.

30 September 2017

1 reference

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Autophagy is activated for cell survival after endoplasmic reticulum stress

30 September 2017

1 reference

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Restricting apoptosis for postmitotic cell survival and its relevance to cancer

30 September 2017

1 reference

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Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP.

30 September 2017

1 reference

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Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis

30 September 2017

1 reference

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Development by self-digestion: molecular mechanisms and biological functions of autophagy

30 September 2017

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Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis

30 September 2017

1 reference

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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

30 September 2017

1 reference

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Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

Interleukin 1 is potent modulator of insulin secretion from isolated rat islets of Langerhans

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

Autophagy in human type 2 diabetes pancreatic beta cells.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

Lack of Apaf-1 expression confers resistance to cytochrome c-driven apoptosis in cardiomyocytes

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315295

Preliminary characterization of calcium binding in islet-cell plasma membranes

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28212395

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpression of pre-pro-cholecystokinin stimulates beta-cell proliferation in mouse and human islets with retention of islet function

1 reference

9 February 2024

https://opencitations.net/index/api/v1/citations/10.1210/ME.2008-0255

Identifiers

DOI

10.1371/JOURNAL.PONE.0172567

1 reference

13 August 2017

1 reference

13 August 2017

1 reference