Investigating Wnt signaling: a chemogenomic safari (Q36294110)

13 August 2017

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title

Investigating Wnt signaling: a chemogenomic safari (English)

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13 August 2017

Michael McMillan

1

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PubMed ID

16243267

13 August 2017

Michael Kahn

series ordinal

2

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13 August 2017

1 November 2005

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13 August 2017

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13 August 2017

10

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13 August 2017

21

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13 August 2017

1467-1474

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A small-molecule agonist of the Wnt signaling pathway

13 August 2017

1 reference

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7 January 2021

Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation

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7 January 2021

High-throughput siRNA-based functional target validation

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7 January 2021

Photo-affinity labeling strategies in identifying the protein ligands of bioactive small molecules: examples of targeted synthesis of drug analog photoprobes

1 reference

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7 January 2021

Target identification strategies in chemical genetics

1 reference

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7 January 2021

Target identification in chemical genetics: the (often) missing link

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7 January 2021

Small-molecule kinase-inhibitor target assessment

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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

Chemical genetics for therapeutic target mining

1 reference

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7 January 2021

Chemical genomics: probing protein function using small molecules

1 reference

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7 January 2021

Forward & reverse chemical genetics using SPOS-based combinatorial chemistry

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7 January 2021

Chemical genetics: toward the next generation of molecular medicines

1 reference

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7 January 2021

Strategies for facilitated forward chemical genetics

1 reference

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7 January 2021

From large networks to small molecules

1 reference

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7 January 2021

Zebrafish as a genomics research model

1 reference

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7 January 2021

Complex phenotypic assays in high-throughput screening

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7 January 2021

Design and synthesis of novel bioactive peptides and peptidomimetics

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7 January 2021

The specificities of protein kinase inhibitors: an update

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7 January 2021

Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

Amphiphilic Secondary Structure: Design of Peptide Hormones

1 reference

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7 January 2021

Highly efficient and versatile synthesis of libraries of constrained beta-strand mimetics

1 reference

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7 January 2021

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

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7 January 2021

Emerging classes of protein-protein interaction inhibitors and new tools for their development

1 reference

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7 January 2021

Molecular causes of colon cancer

1 reference

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7 January 2021

The promise and perils of Wnt signaling through beta-catenin.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

Convergence of Wnt, beta-catenin, and cadherin pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

WNT and beta-catenin signalling: diseases and therapies

1 reference

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7 January 2021

Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis

1 reference

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7 January 2021

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

Identification of c-MYC as a target of the APC pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

Analysis of human transcriptomes.

1 reference

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7 January 2021

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1 reference

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7 January 2021

Survivin study: what is the next wave?

1 reference

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7 January 2021

Validating survivin as a cancer therapeutic target

1 reference

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7 January 2021

Survivin and molecular pathogenesis of colorectal cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression

1 reference

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7 January 2021

p300 Transcriptional Repression Is Mediated by SUMO Modification

1 reference

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7 January 2021

Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression

1 reference

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7 January 2021

beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system

1 reference

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7 January 2021

Beta-catenin signaling is required for neural differentiation of embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells.

1 reference

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7 January 2021

Neuroplasticity failure in Alzheimer's disease: bridging the gap between plaques and tangles

1 reference

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7 January 2021

Presenilin function: connections to Alzheimer's disease and signal transduction

1 reference

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7 January 2021

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

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7 January 2021

Notch is expressed in adult brain, is coexpressed with presenilin-1, and is altered in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

Dual control of neurogenesis by PC3 through cell cycle inhibition and induction of Math1

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903613-5

7 January 2021

The critical role of cyclin D2 in adult neurogenesis

1 reference

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7 January 2021

Specific inhibition of CBP/beta-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation

1 reference

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7 January 2021

Applying the principles of stem-cell biology to cancer

1 reference

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7 January 2021

Neural computing in cancer drug development: predicting mechanism of action

1 reference

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7 January 2021

Use of the Kohonen self-organizing map to study the mechanisms of action of chemotherapeutic agents.

1 reference

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7 January 2021

10.1016/S1359-6446(05)03613-5

Identifiers

DOI

1 reference

13 August 2017

1 reference

PubMed ID

16243267