Combined cardiomyocyte PKCδ and PKCε gene deletion uncovers their central role in restraining developmental and reactive heart growth (Q36367548)

13 August 2017

Combined cardiomyocyte PKCδ and PKCε gene deletion uncovers their central role in restraining developmental and reactive heart growth (English)

1 reference

13 August 2017

Moshi Song

1

1 reference

13 August 2017

Scot J Matkovich

2

1 reference

13 August 2017

Yan Zhang

3

1 reference

13 August 2017

Daniel J Hammer

4

1 reference

13 August 2017

Gerald W Dorn

5

1 reference

13 August 2017

21 April 2015

1 reference

13 August 2017

1 reference

13 August 2017

8

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13 August 2017

373

1 reference

13 August 2017

ra39

1 reference

describes a project that uses

13 August 2017

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

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Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs

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Epitranscriptional orchestration of genetic reprogramming is an emergent property of stress-regulated cardiac microRNAs.

30 September 2017

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Evolution of the eukaryotic protein kinases as dynamic molecular switches

30 September 2017

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PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria

30 September 2017

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Periostin identified as a potential biomarker of prostate cancer by iTRAQ-proteomics analysis of prostate biopsy

30 September 2017

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Transient regenerative potential of the neonatal mouse heart

30 September 2017

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Differential regulation of gene expression by protein kinase C isozymes as determined by genome-wide expression analysis

30 September 2017

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Protein kinase Cα as a heart failure therapeutic target

30 September 2017

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Receptor-Independent Cardiac Protein Kinase Cα Activation by Calpain-Mediated Truncation of Regulatory Domains

30 September 2017

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Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach

30 September 2017

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IL-6 loss causes ventricular dysfunction, fibrosis, reduced capillary density, and dramatically alters the cell populations of the developing and adult heart

30 September 2017

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Genetic manipulation of periostin expression in the heart does not affect myocyte content, cell cycle activity, or cardiac repair

30 September 2017

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Structural basis of protein kinase C isoform function

30 September 2017

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Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling

30 September 2017

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Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure

30 September 2017

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The beta-catenin/T-cell factor/lymphocyte enhancer factor signaling pathway is required for normal and stress-induced cardiac hypertrophy

30 September 2017

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Protein kinase cascades in the regulation of cardiac hypertrophy

30 September 2017

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PMA induces the MUC5AC respiratory mucin in human bronchial epithelial cells, via PKC, EGF/TGF-alpha, Ras/Raf, MEK, ERK and Sp1-dependent mechanisms.

30 September 2017

1 reference

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Hypertrophy of the heart: a new therapeutic target?

30 September 2017

1 reference

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PKC-alpha regulates cardiac contractility and propensity toward heart failure

30 September 2017

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Protein Kinase Cα Negatively Regulates Systolic and Diastolic Function in Pathological Hypertrophy

30 September 2017

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Stabilization of beta-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth

30 September 2017

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Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta

30 September 2017

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PKC alpha regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2)

30 September 2017

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Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC.

30 September 2017

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Cytoplasmic signaling pathways that regulate cardiac hypertrophy

30 September 2017

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The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

30 September 2017

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Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy

30 September 2017

1 reference

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Cardiotrophic effects of protein kinase C epsilon: analysis by in vivo modulation of PKCepsilon translocation

30 September 2017

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Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation

30 September 2017

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Sp1 phosphorylation by Erk 2 stimulates DNA binding

30 September 2017

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The extended protein kinase C superfamily

30 September 2017

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Expression of protein kinase C beta in the heart causes hypertrophy in adult mice and sudden death in neonates.

30 September 2017

1 reference

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Transgenic Galphaq overexpression induces cardiac contractile failure in mice

30 September 2017

1 reference

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Novel role for Sp1 in phorbol ester enhancement of human platelet thromboxane receptor gene expression

30 September 2017

1 reference

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Protein kinase C and lipid signaling for sustained cellular responses

30 September 2017

1 reference

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The role of protein kinase C in cell surface signal transduction and tumour promotion

30 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677479

30 September 2017

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1855

Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies

21 January 2018

1 reference

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Ischemic protection and myofibrillar cardiomyopathy: dose-dependent effects of in vivo deltaPKC inhibition

30 September 2017

1 reference

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A novel nociceptor signaling pathway revealed in protein kinase C epsilon mutant mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677479

Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677479

Translocation assays of protein kinase C activation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677479

Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677479

Cardiac hypertrophy served with protein kinase Cepsilon: delta isoform substitution available at additional cost

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677479

Increased collagen deposition and diastolic dysfunction but preserved myocardial hypertrophy after pressure overload in mice lacking PKCepsilon

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677479

The role of Sp1 in BMP2-up-regulated Erk2 gene expression

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677479

Cardiotrophic Effects of Protein Kinase C : Analysis by In Vivo Modulation of PKC Translocation

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1855

Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy

21 January 2018

1 reference

12 December 2020

Epsilon protein kinase C in pathological myocardial hypertrophy. Analysis by combined transgenic expression of translocation modifiers and Galphaq

1 reference

12 December 2020

Phenotyping hypertrophy: eschew obfuscation

1 reference

12 December 2020

Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Gαq/Gα11 in cardiomyocytes

1 reference

12 December 2020

10.1126/SCISIGNAL.AAA1855

Identifiers

DOI

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

25900833

1 reference