Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor. (Q36372640)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17872377%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor (English)

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7 January 2020

author

Jean-Pierre Vilardaga

2

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7 January 2020

author name string

Thomas Dean

1

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7 January 2020

John T Potts

3

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7 January 2020

Thomas J Gardella

4

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publication date

13 September 2007

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7 January 2020

published in

Molecular Endocrinology

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7 January 2020

volume

22

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7 January 2020

issue

1

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7 January 2020

page(s)

156-166

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Role of amino acid side chains in region 17-31 of parathyroid hormone (PTH) in binding to the PTH receptor

7 January 2020

cites work

1 reference

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Mechanisms of ligand binding to the parathyroid hormone (PTH)/PTH-related protein receptor: selectivity of a modified PTH(1-15) radioligand for GalphaS-coupled receptor conformations

30 September 2017

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Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism.

30 September 2017

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Continuous PTH and PTHrP infusion causes suppression of bone formation and discordant effects on 1,25(OH)2 vitamin D.

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Novel parathyroid hormone (PTH) antagonists that bind to the juxtamembrane portion of the PTH/PTH-related protein receptor

30 September 2017

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30 September 2017

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30 September 2017

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Parathyroid hormone receptor recycling: role of receptor dephosphorylation and beta-arrestin

30 September 2017

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A highly effective dominant negative alpha s construct containing mutations that affect distinct functions inhibits multiple Gs-coupled receptor signaling pathways

30 September 2017

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Parathyroid hormone (PTH)-(1-14) and -(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor

30 September 2017

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Maximal rate and nucleotide dependence of rhodopsin-catalyzed transducin activation: initial rate analysis based on a double displacement mechanism

30 September 2017

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Dual signaling and ligand selectivity of the human PTH/PTHrP receptor

30 September 2017

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Histidine at position 5 is the specificity "switch" between two parathyroid hormone receptor subtypes

30 September 2017

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Converting parathyroid hormone-related peptide (PTHrP) into a potent PTH-2 receptor agonist

30 September 2017

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A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor

30 September 2017

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Parathyroid hormone (PTH)-PTH-related peptide hybrid peptides reveal functional interactions between the 1-14 and 15-34 domains of the ligand

30 September 2017

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Characterization and agonist-induced down-regulation of parathyroid hormone receptors in clonal rat osteosarcoma cells

30 September 2017

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Non-homologous sequences of parathyroid hormone and the parathyroid hormone related peptide bind to a common receptor on ROS 17/2.8 cells

30 September 2017

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The complex regulation of receptor-coupled G-proteins

30 September 2017

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Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma

28 June 2018

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The bovine renal parathyroid hormone (PTH) receptor has equal affinity for two different amino acid sequences: the receptor binding domains of PTH and PTH-related protein are located within the 14-34 region

28 June 2018

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The mid-region of parathyroid hormone (1-34) serves as a functional docking domain in receptor activation.

28 June 2018

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21 September 2018

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21 September 2018

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21 September 2018

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21 September 2018

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Measurement of agonist and antagonist ligand-binding parameters at the human parathyroid hormone type 1 receptor: evaluation of receptor states and modulation by guanine nucleotide.

21 September 2018

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21 September 2018

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12 December 2020

Safety and tolerability of subcutaneous PTHrP(1-36) in healthy human volunteers: a dose escalation study.

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12 December 2020

PTHrP and skeletal development

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12 December 2020

Identification of key components in the irreversibility of salmon calcitonin binding to calcitonin receptors

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12 December 2020

Selective ligand-induced stabilization of active and desensitized parathyroid hormone type 1 receptor conformations

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12 December 2020

Short-term, high-dose parathyroid hormone-related protein as a skeletal anabolic agent for the treatment of postmenopausal osteoporosis

1 reference

12 December 2020

Identification of a Mg(2+)- and guanyl nucleotide-dependent glucagon receptor cycle by use of permeabilized canine hepatocytes

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12 December 2020

Identifiers

DOI

10.1210/ME.2007-0274

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17872377%20AND%20SRC:MED&resulttype=core&format=json

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mapped directly with Wikidata item

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7 January 2020

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