Insulin fails to enhance mTOR phosphorylation, mitochondrial protein synthesis, and ATP production in human skeletal muscle without amino acid replacement (Q36382522)

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English	Insulin fails to enhance mTOR phosphorylation, mitochondrial protein synthesis, and ATP production in human skeletal muscle without amino acid replacement	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

Insulin fails to enhance mTOR phosphorylation, mitochondrial protein synthesis, and ATP production in human skeletal muscle without amino acid replacement (English)

1 reference

Europe PubMed Central

13 August 2017

phosphorylation

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2

object named as

Kevin R Short

1 reference

Europe PubMed Central

13 August 2017

author name string

Rocco Barazzoni

1

1 reference

Europe PubMed Central

13 August 2017

Yan Asmann

3

1 reference

Europe PubMed Central

13 August 2017

Jill M Coenen-Schimke

4

1 reference

Europe PubMed Central

13 August 2017

Matthew M Robinson

5

1 reference

Europe PubMed Central

13 August 2017

K Sreekumaran Nair

6

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Europe PubMed Central

13 August 2017

publication date

11 September 2012

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Europe PubMed Central

13 August 2017

American Journal of Physiology - Endocrinology and Metabolism

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Europe PubMed Central

13 August 2017

303

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Europe PubMed Central

13 August 2017

E1117-25

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Europe PubMed Central

13 August 2017

9

1 reference

Europe PubMed Central

13 August 2017

Exercise, amino acids, and aging in the control of human muscle protein synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

Bidirectional transport of amino acids regulates mTOR and autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

Enhancement of muscle mitochondrial function by growth hormone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

Effect of insulin on human skeletal muscle protein synthesis is modulated by insulin-induced changes in muscle blood flow and amino acid availability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

New functions for amino acids: effects on gene transcription and translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

Reduced amino acid availability inhibits muscle protein synthesis and decreases activity of initiation factor eIF2B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

Effect of physiologic hyperinsulinemia on skeletal muscle protein synthesis and breakdown in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

30 September 2017

Phosphorylation of eIF2alpha is involved in the signaling of indispensable amino acid deficiency in the anterior piriform cortex of the brain in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

28 June 2018

Chronic Akt activation accentuates aging-induced cardiac hypertrophy and myocardial contractile dysfunction: role of autophagy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

21 September 2018

Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

21 September 2018

PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

21 September 2018

Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

21 September 2018

Mitochondrial and sarcoplasmic proteins, but not myosin heavy chain, are sensitive to leucine supplementation in old rat skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

21 September 2018

Model to assess muscle protein turnover: domain of validity using amino acyl-tRNA vs. surrogate measures of precursor pool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

21 September 2018

Differential regulation of protein dynamics in splanchnic and skeletal muscle beds by insulin and amino acids in healthy human subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492854

21 September 2018

Effects of branched-chain-enriched amino acids and insulin on forearm leucine kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/22967500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of insulin's anabolic effect on muscle: measurements of muscle protein synthesis and breakdown using aminoacyl-tRNA and other surrogate measures

1 reference

https://pubmed.ncbi.nlm.nih.gov/22967500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22967500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis in skeletal muscle and whole body in response to euglycemic hyperinsulinemia in normal adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/22967500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mass spectrometric methods for determination of [13C]Leucine enrichment in human muscle protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22967500

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPENDO.00067.2012

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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