Amyloid excess in Alzheimer's disease: what is cholesterol to be blamed for? (Q36524959)

14 August 2017

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title

Amyloid excess in Alzheimer's disease: what is cholesterol to be blamed for? (English)

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14 August 2017

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Maria Dolores Ledesma

series ordinal

1

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PubMed ID

16814780

14 August 2017

Carlos G Dotti

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2

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PubMed ID

16814780

14 August 2017

language of work or name

English

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publication date

23 June 2006

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14 August 2017

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14 August 2017

580

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14 August 2017

23

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14 August 2017

5525-5532

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Physiological roles of amyloid-beta and implications for its removal in Alzheimer's disease

14 August 2017

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Alzheimer's disease and Abeta toxicity: from top to bottom

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Mutant genes in familial Alzheimer's disease and transgenic models

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Cholesterol in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Functional rafts in cell membranes

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Lipid rafts and signal transduction

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Neuronal polarity: essential role of protein-lipid complexes in axonal sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Proper axonal distribution of PrP(C) depends on cholesterol-sphingomyelin-enriched membrane domains and is developmentally regulated in hippocampal neurons

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Lipid rafts and caveolae as portals for endocytosis: new insights and common mechanisms

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

CNS synaptogenesis promoted by glia-derived cholesterol

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Do sterols reduce proton and sodium leaks through lipid bilayers?

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Uptake of lipoproteins for axonal growth of sympathetic neurons

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Lipid droplets: a unified view of a dynamic organelle

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Neuronal localization of sterol regulatory element binding protein-1 in the rodent and primate brain: a light and electron microscopic immunocytochemical study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Regulation of cholesterol homeostasis by the liver X receptors in the central nervous system

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Statins and the risk of dementia

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

21 January 2018

Head injury and dementia

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Use of statins in CNS disorders

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

LRP in Alzheimer's disease: friend or foe?

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Intracellular calcium changes in neuronal cells induced by Alzheimer's beta-amyloid protein are blocked by estradiol and cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Neuronal membrane cholesterol loss enhances amyloid peptide generation

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Abeta generation in vivo

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Alzheimer's disease: the cholesterol connection

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

Brain Cholesterol, Statins and Alzheimer’s Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.06.038

10.1016/J.FEBSLET.2006.06.038

21 January 2018

Identifiers

DOI

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14 August 2017

1 reference

PubMed ID

16814780