CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia. (Q36545966)

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28 February 2020

title

CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia (English)

1 reference

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28 February 2020

5

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28 February 2020

Jerome Tamburini

9

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28 February 2020

author name string

Sarah Bertoli

1

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28 February 2020

Helena Boutzen

2

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28 February 2020

Laure David

3

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28 February 2020

Clément Larrue

4

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28 February 2020

Anne Fernandez-Vidal

6

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28 February 2020

Lingli Yuan

7

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28 February 2020

Marie-Anne Hospital

8

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28 February 2020

Cécile Demur

10

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28 February 2020

Eric Delabesse

11

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28 February 2020

Estelle Saland

12

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28 February 2020

Jean-Emmanuel Sarry

13

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28 February 2020

Marie-Odile Galcera

14

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28 February 2020

Véronique Mansat-De Mas

15

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28 February 2020

Christine Dozier

17

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28 February 2020

Christian Récher

18

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28 February 2020

Stéphane Manenti

19

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28 February 2020

Christine Didier

16

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28 February 2020

language of work or name

English

0 references

publication date

1 November 2015

1 reference

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28 February 2020

1 reference

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28 February 2020

volume

6

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28 February 2020

issue

35

1 reference

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28 February 2020

page(s)

38061-38078

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Therapeutic targeting the cell division cycle 25 (CDC25) phosphatases in human acute myeloid leukemia--the possibility to target several kinases through inhibition of the various CDC25 isoforms.

28 February 2020

cites work

1 reference

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30 September 2017

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30 September 2017

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CDC25A targeting by miR-483-3p decreases CCND-CDK4/6 assembly and contributes to cell cycle arrest.

30 September 2017

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The STAT5 Inhibitor Pimozide Displays Efficacy in Models of Acute Myelogenous Leukemia Driven by FLT3 Mutations

30 September 2017

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30 September 2017

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30 September 2017

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Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα.

30 September 2017

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Phase IB study of the FLT3 kinase inhibitor midostaurin with chemotherapy in younger newly diagnosed adult patients with acute myeloid leukemia

30 September 2017

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Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

30 September 2017

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C/EBPα Dysregulation in AML and ALL

30 September 2017

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CDC25 phosphatase inhibitors: an update

30 September 2017

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30 September 2017

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Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

30 September 2017

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Upregulation of the CDC25A phosphatase down-stream of the NPM/ALK oncogene participates to anaplastic large cell lymphoma enhanced proliferation.

30 September 2017

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CDC25A: a rebel within the CDC25 phosphatases family?

30 September 2017

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IRC-083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells

30 September 2017

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30 September 2017

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CDC25A phosphatase: a rate-limiting oncogene that determines genomic stability

30 September 2017

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Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model

30 September 2017

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CDC25 phosphatases in cancer cells: key players? Good targets?

30 September 2017

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30 September 2017

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30 September 2017

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Internal tandem duplication mutation of FLT3 blocks myeloid differentiation through suppression of C/EBPα expression

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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21 September 2018

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21 September 2018

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21 September 2018

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21 September 2018

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Aberrant pre-mRNA splicing of a highly conserved cell cycle regulator, CDC25C, in myelodysplastic syndromes.

21 September 2018

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The STAT3 transcription factor is a target for the Myc and riboblastoma proteins on the Cdc25A promoter.

21 September 2018

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Antileukemic activity of rapamycin in acute myeloid leukemia.

21 September 2018

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Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells

21 September 2018

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Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors

21 September 2018

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Cell adhesion regulates CDC25A expression and proliferation in acute myeloid leukemia

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26515730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Internal tandem duplication of the flt3 gene found in acute myeloid leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26515730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26515730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.5706

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26515730%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26515730%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

26515730

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26515730%20AND%20SRC:MED&resulttype=core&format=json