Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults (Q36602173)

15 August 2017

Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults (English)

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15 August 2017

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Yisheng Yang

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15 August 2017

Benny Hung-Junn Chang

series ordinal

2

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15 August 2017

Lawrence Chan

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3

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15 August 2017

29 November 2012

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15 August 2017

13

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based on heuristic

inferred from page(s)

published in

EMBO Molecular Medicine

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15 August 2017

5

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15 August 2017

1

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15 August 2017

92-104

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describes a project that uses

15 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3569656/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

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Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians: ADCY5 and GLIS3 variants may predispose to type 2 diabetes

30 September 2017

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The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.

30 September 2017

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Variants in GLIS3 and CRY2 are associated with type 2 diabetes and impaired fasting glucose in Chinese Hans

30 September 2017

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Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children

30 September 2017

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Pancreatic beta cells require NeuroD to achieve and maintain functional maturity

30 September 2017

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Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents

30 September 2017

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

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Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression

30 September 2017

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Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function

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Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

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The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription

30 September 2017

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Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion

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Glucolipotoxicity: fuel excess and beta-cell dysfunction.

30 September 2017

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Molecular regulation of pancreatic beta-cell mass development, maintenance, and expansion

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Molecular control of cell cycle progression in the pancreatic beta-cell

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Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

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Five stages of evolving beta-cell dysfunction during progression to diabetes

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Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.

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Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors

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GLIS3, a novel member of the GLIS subfamily of Kruppel-like zinc finger proteins with repressor and activation functions

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Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

30 September 2017

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Rat endocrine pancreatic development in relation to two homeobox gene products (Pdx-1 and Nkx 6.1)

30 September 2017

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PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

30 September 2017

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Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.

30 September 2017

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Pancreatic beta cells express a diverse set of homeobox genes

30 September 2017

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Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas

30 September 2017

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Insulin-promoter-factor 1 is required for pancreas development in mice

30 September 2017

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IPF1, a homeodomain-containing transactivator of the insulin gene

30 September 2017

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Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic rats

30 September 2017

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Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

30 September 2017

1 reference

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A murine model of neonatal diabetes mellitus in Glis3-deficient mice

20 September 2018

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Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism.

20 September 2018

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mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor

20 September 2018

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Crossref

https://api.crossref.org/works/10.1002%2FEMMM.201201398

Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23197416

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/EMMM.201201398

1 reference

15 August 2017

1 reference

15 August 2017

1 reference