Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α. (Q36602744)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23395173%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α (English)

1 reference

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23 February 2020

main subject

pulmonary hypertension

1 reference

2

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23 February 2020

Suh Young Jeong

3

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23 February 2020

author name string

Manik C Ghosh

1

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23 February 2020

Gennadiy Kovtunovych

4

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23 February 2020

Hayden Ollivierre-Wilson

5

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23 February 2020

Audrey Noguchi

6

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23 February 2020

Tiffany Tu

7

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23 February 2020

Thomas Senecal

8

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23 February 2020

Gabrielle Robinson

9

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23 February 2020

Daniel R Crooks

10

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23 February 2020

Wing-Hang Tong

11

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23 February 2020

Kavitha Ramaswamy

12

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23 February 2020

Anamika Singh

13

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23 February 2020

Brian B Graham

14

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23 February 2020

Rubin M Tuder

15

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23 February 2020

Zu-Xi Yu

16

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23 February 2020

Michael Eckhaus

17

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23 February 2020

Jaekwon Lee

18

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23 February 2020

Danielle A Springer

19

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23 February 2020

Tracey A Rouault

20

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23 February 2020

publication date

1 February 2013

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23 February 2020

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23 February 2020

volume

17

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23 February 2020

page(s)

271-281

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23 February 2020

issue

2

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A systematic survey of loss-of-function variants in human protein-coding genes

23 February 2020

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1 reference

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Two to tango: regulation of Mammalian iron metabolism

30 September 2017

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The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice.

30 September 2017

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An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis

30 September 2017

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Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing

30 September 2017

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Deletion of hepatic Ctr1 reveals its function in copper acquisition and compensatory mechanisms for copper homeostasis

30 September 2017

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Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice

30 September 2017

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30 September 2017

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von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis

30 September 2017

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Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency

30 September 2017

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Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

30 September 2017

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30 September 2017

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20 September 2018

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20 September 2018

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20 September 2018

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20 September 2018

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Dysregulation of the HIF pathway due to VHL mutation causing severe erythrocytosis and pulmonary arterial hypertension

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23395173

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2012.12.016

1 reference

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23 February 2020

1 reference

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23 February 2020

1 reference

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