Principles and effects of microRNA-mediated post-transcriptional gene regulation. (Q36617803)

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20 December 2019

review article

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title

Principles and effects of microRNA-mediated post-transcriptional gene regulation (English)

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20 December 2019

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2

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20 December 2019

author name string

B M Engels

series ordinal

1

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20 December 2019

language of work or name

English

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publication date

1 October 2006

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20 December 2019

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20 December 2019

volume

25

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20 December 2019

issue

46

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20 December 2019

page(s)

6163-6169

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209909

20 December 2019

exact match

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The widespread impact of mammalian MicroRNAs on mRNA repression and evolution

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Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

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MicroRNAs regulate brain morphogenesis in zebrafish

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Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

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Kinetic analysis of the RNAi enzyme complex

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

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Argonaute2, a link between genetic and biochemical analyses of RNAi

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The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb

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The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development

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Canalization of development by microRNAs

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MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function

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A microRNA in a multiple-turnover RNAi enzyme complex

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A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

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Disruption of GW bodies impairs mammalian RNA interference

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Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila

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Involvement of microRNA in AU-rich element-mediated mRNA instability

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Human MicroRNA targets

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A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

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Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

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Functional siRNAs and miRNAs Exhibit Strand Bias

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Identification of many microRNAs that copurify with polyribosomes in mammalian neurons

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A combined computational-experimental approach predicts human microRNA targets

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Substrate requirements for let-7 function in the developing zebrafish embryo

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A Genome-Wide Map of Conserved MicroRNA Targets in C. elegans

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

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The role of PACT in the RNA silencing pathway

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Cleavage of the siRNA passenger strand during RISC assembly in human cells

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R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

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Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1

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Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

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7 January 2021

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

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7 January 2021

RISC is a 5' phosphomonoester-producing RNA endonuclease

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7 January 2021

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

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7 January 2021

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

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7 January 2021

Identification of novel argonaute-associated proteins

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7 January 2021

Slicer function of Drosophila Argonautes and its involvement in RISC formation

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7 January 2021

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

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7 January 2021

miRNP:mRNA association in polyribosomes in a human neuronal cell line.

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7 January 2021

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

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7 January 2021

The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

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7 January 2021

Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome

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Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex

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Short RNAs repress translation after initiation in mammalian cells.

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A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

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Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis

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Inhibition of translational initiation by Let-7 MicroRNA in human cells

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Biochemical specialization within Arabidopsis RNA silencing pathways

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Computational identification of microRNA targets.

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A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

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7 January 2021

Purified Argonaute2 and an siRNA form recombinant human RISC

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7 January 2021

Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells

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Identification of eight members of the Argonaute family in the human genome

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7 January 2021

Asymmetry in the assembly of the RNAi enzyme complex

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The RNA-induced silencing complex is a Mg2+-dependent endonuclease.

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Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation

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7 January 2021

Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene.

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7 January 2021

Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies

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7 January 2021

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

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7 January 2021

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

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7 January 2021

Crystal structure of Argonaute and its implications for RISC slicer activity

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7 January 2021

Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution

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Identification of Drosophila MicroRNA targets

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The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans

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RISC assembly defects in the Drosophila RNAi mutant armitage.

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A protein sensor for siRNA asymmetry

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Control of translation and mRNA degradation by miRNAs and siRNAs

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7 January 2021

Recapitulation of short RNA-directed translational gene silencing in vitro

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7 January 2021

MicroRNA function in animal development

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7 January 2021

MicroRNAs direct rapid deadenylation of mRNA

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7 January 2021

Structure and conserved RNA binding of the PAZ domain

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209909

7 January 2021

MicroRNA-directed cleavage of HOXB8 mRNA

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7 January 2021

Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

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7 January 2021

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

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7 January 2021

RNAi-mediated gene silencing in non-human primates.

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209909

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17028595%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

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