Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology? (Q36620178)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22765297%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22765297%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22765297%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1

Philip C Calder

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 March 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22765297%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Clinical Pharmacology

7 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22765297%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

75

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22765297%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22765297%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

645-662

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22765297%20AND%20SRC:MED&resulttype=core&format=json

Fatty acids and inflammation: the cutting edge between food and pharma.

7 February 2020

cites work

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30 September 2017

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30 September 2017

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30 September 2017

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Omega 3 fatty acids (fish oil) for maintenance of remission in ulcerative colitis

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis

30 September 2017

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30 September 2017

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Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1

30 September 2017

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Immunomodulation by polyunsaturated fatty acids: impact on T-cell signaling.

30 September 2017

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Regulation of T-cell receptor signalling by membrane microdomains

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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A role for lipid rafts in immune cell signaling

30 September 2017

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30 September 2017

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Influence of age and dietary fish oil on plasma soluble adhesion molecule concentrations

30 September 2017

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Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing

30 September 2017

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A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response

30 September 2017

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Fish oil decreases macrophage tumor necrosis factor gene transcription by altering the NF kappa B activity

30 September 2017

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30 September 2017

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Polyunsaturated fatty acids inhibit T cell signal transduction by modification of detergent-insoluble membrane domains

30 September 2017

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Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

30 September 2017

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Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

30 September 2017

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Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease

30 September 2017

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Eicosanoids in rheumatoid arthritis.

30 September 2017

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Dietary omega-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils

30 September 2017

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Prostaglandin E2 regulation of the immune response

30 September 2017

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Validation of a meta-analysis: the effects of fish oil in rheumatoid arthritis

30 September 2017

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Dietary fish oil modulates macrophage fatty acids and decreases arthritis susceptibility in mice

30 September 2017

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Effect of dietary supplementation with fish oil lipids on mild asthma

30 September 2017

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Effects of manipulation of dietary fatty acids on clinical manifestations of rheumatoid arthritis

30 September 2017

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Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases

30 September 2017

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Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: comparison between young and older women

30 September 2017

1 reference

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Incorporation of fatty acids from fish oil and olive oil into colonic mucosal lipids and effects upon eicosanoid synthesis in inflammatory bowel disease

30 September 2017

1 reference

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Influence of dietary n-3 fatty acids on macrophage glycerophospholipid molecular species and peptidoleukotriene synthesis

30 September 2017

1 reference

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Treatment of ulcerative colitis with fish oil supplementation: a prospective 12 month randomised controlled trial

30 September 2017

1 reference

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Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor

30 September 2017

1 reference

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Dietary Supplementation with Fish Oil in Ulcerative Colitis

30 September 2017

1 reference

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Docosahexaenoic acid and eicosapentaenoic acid are converted by 3T3-L1 adipocytes to N-acyl ethanolamines with anti-inflammatory properties.

30 September 2017

1 reference

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Reduction of cardiovascular risk factors with longterm fish oil treatment in early rheumatoid arthritis.

28 June 2018

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Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay

28 June 2018

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Dietary n-3 polyunsaturated fatty acids prevent the development of atherosclerotic lesions in mice. Modulation of macrophage secretory activities

28 June 2018

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Incorporation of fatty acids by concanavalin A-stimulated lymphocytes and the effect on fatty acid composition and membrane fluidity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Fatty acid intake and Kupffer cell function: fish oil alters eicosanoid and monokine production to endotoxin stimulation.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Alterations in human leukocyte function induced by ingestion of eicosapentaenoic acid

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Effect of eicosapentaenoic acid in asthma

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Clinical and immunologic effects

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Uptake and incorporation of saturated and unsaturated fatty acids into macrophage lipids and their effect upon macrophage adhesion and phagocytosis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

n-3 fatty acids and leukocyte chemotaxis. Effects in hyperlipidemia and dose-response studies in healthy men.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Docosahexaenoic acid inhibits the adhesion of flowing neutrophils to cytokine stimulated human umbilical vein endothelial cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Fish oil supplementation decreases serum soluble receptor activator of nuclear factor-kappa B ligand/osteoprotegerin ratio in female patients with rheumatoid arthritis.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

The 2008 ESPEN Sir David Cuthbertson Lecture: Fatty acids and inflammation--from the membrane to the nucleus and from the laboratory bench to the clinic

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Dietary alpha-linolenic acid and health-related outcomes: a metabolic perspective.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

In vivo and in vitro inhibition of monocyte adhesion to endothelial cells and endothelial adhesion molecules by eicosapentaenoic acid.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Human dendritic cell activities are modulated by the omega-3 fatty acid, docosahexaenoic acid, mainly through PPAR(gamma):RXR heterodimers: comparison with other polyunsaturated fatty acids

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Unsaturated fatty acids suppress interleukin-2 production and transferrin receptor expression by concanavalin A-stimulated rat Iymphocytes

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Influence of dietary fatty acids on endocannabinoid and N-acylethanolamine levels in rat brain, liver and small intestine

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Resolvin E1 dampens airway inflammation and hyperresponsiveness in a murine model of asthma

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Dietary docosahexaenoic acid suppresses T cell protein kinase C theta lipid raft recruitment and IL-2 production

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Effects of oils rich in eicosapentaenoic and docosahexaenoic acids on immune cell composition and function in healthy humans.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Effects of highly purified eicosapentaenoic acid on erythrocyte fatty acid composition and leukocyte and colonic mucosa leukotriene B4 production in children with ulcerative colitis

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Dietary intakes and food sources of omega-6 and omega-3 polyunsaturated fatty acids.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Dietary (n-3) polyunsaturated fatty acids remodel mouse T-cell lipid rafts

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Lack of effect of foods enriched with plant- or marine-derived n-3 fatty acids on human immune function.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

LAT displacement from lipid rafts as a molecular mechanism for the inhibition of T cell signaling by polyunsaturated fatty acids

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering raft lipid composition.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Dietary fatty acids influence the production of Th1- but not Th2-type cytokines

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Effect of aerosolized docosahexaenoic acid in a mouse model of atopic asthma

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Dietary fish oil diminishes lymphocyte adhesion to macrophage and endothelial cell monolayers

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Fish oil supplementation inhibits the expression of major histocompatibility complex class II molecules and adhesion molecules on human monocytes.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Human neutrophil chemotactic and degranulating activities of leukotriene B5 (LTB5) derived from eicosapentaenoic acid.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575932

Long-term supplementation with n-3 fatty acids, II: Effect on neutrophil and monocyte chemotaxis

20 September 2018

1 reference

12 December 2020

n-3 fatty acids and cysteinyl-leukotriene formation in humans in vitro, ex vivo, and in vivo

1 reference

12 December 2020

Suppression of T cell signaling by polyunsaturated fatty acids: selectivity in inhibition of mitogen-activated protein kinase and nuclear factor activation

1 reference

12 December 2020

The eicosapentaenoic to docosahexaenoic acid ratio of diets affects the pathogenesis of arthritis in Lew/SSN rats

1 reference

12 December 2020

Comparison of the pro-inflammatory potential of monocytes from healthy adults and those with peripheral arterial disease using an in vitro culture model

1 reference

12 December 2020

Vitamin E status during dietary fish oil supplementation in rheumatoid arthritis

1 reference

12 December 2020

Effect of low-to-moderate amounts of dietary fish oil on neutrophil lipid composition and function

1 reference

12 December 2020

Eicosapentaenoic acid inhibits prostaglandin D2 generation by inhibiting cyclo-oxygenase-2 in cultured human mast cells

1 reference

12 December 2020

Dietary supplementation with fish oil rich in omega-3 polyunsaturated fatty acids in children with bronchial asthma

1 reference

12 December 2020

Effects of dietary lipid manipulation upon inflammatory mediator production by murine macrophages

1 reference

12 December 2020

Dietary supplementation with gamma-linolenic acid or fish oil decreases T lymphocyte proliferation in healthy older humans

1 reference

12 December 2020

Effects of omega-3 fatty acids on lipids and glycemic control in type II diabetes and the metabolic syndrome and on inflammatory bowel disease, rheumatoid arthritis, renal disease, systemic lupus erythematosus, and osteoporosis

1 reference

12 December 2020

The effect of dietary lipid manipulation on rat lymphocyte subsets and proliferation

1 reference

12 December 2020

Decreased interleukin-1 beta levels in plasma from rheumatoid arthritis patients after dietary supplementation with n-3 polyunsaturated fatty acids

1 reference

12 December 2020

Polyunsaturated fatty acids suppress human peripheral blood lymphocyte proliferation and interleukin-2 production

1 reference

12 December 2020

Encapsulated fish oil enriched in alpha-tocopherol alters plasma phospholipid and mononuclear cell fatty acid compositions but not mononuclear cell functions

1 reference

12 December 2020

Effect of fatty acids on the proliferation of concanavalin A-stimulated rat lymph node lymphocytes

1 reference

12 December 2020

Cod liver oil inhibits neutrophil and monocyte chemotaxis in healthy males

1 reference

12 December 2020

The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells

1 reference

12 December 2020

Fish oil and antioxidants alter the composition and function of circulating mononuclear cells in Crohn disease

1 reference

12 December 2020

Characterization and biologic properties of 5,12-dihydroxy derivatives of eicosapentaenoic acid, including leukotriene B5 and the double lipoxygenase product

1 reference

12 December 2020

Clinical and biochemical effects of dietary fish oil supplements in rheumatoid arthritis

1 reference

12 December 2020

The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells

1 reference

12 December 2020

Dietary lipids modify the cytokine response to bacterial lipopolysaccharide in mice

1 reference

12 December 2020

Dietary fish oil reduces intercellular adhesion molecule 1 and scavenger receptor expression on murine macrophages

1 reference

12 December 2020

Docosahexaenoic and eicosapentaenoic acids inhibit in vitro human endothelial cell production of interleukin-6

1 reference

12 December 2020

Immunomodulatory effects of (n-3) fatty acids: putative link to inflammation and colon cancer

1 reference

12 December 2020

(n-3) Polyunsaturated fatty acids modulate the expression of functionally associated molecules on human monocytes in vitro

1 reference

12 December 2020

Eicosapentaenoic and docosahexaenoic acids alter rat spleen leukocyte fatty acid composition and prostaglandin E2 production but have different effects on lymphocyte functions and cell-mediated immunity

1 reference

12 December 2020

Effect of dietary intake of omega-3 and omega-6 fatty acids on severity of asthma in children

1 reference

12 December 2020

Therapeutic potential of fish oil in the treatment of ulcerative colitis

1 reference

12 December 2020

Supplementation with n-3 fatty acids from fish oil in chronic inflammatory bowel disease--a randomized, placebo-controlled, double-blind cross-over trial

1 reference

12 December 2020

Prostaglandin E2 production and T cell function after fish-oil supplementation: response to antioxidant cosupplementation

1 reference

12 December 2020

Inhibitory effect of fish oil N-3 polyunsaturated fatty acids on the expression of endothelial cell adhesion molecules

1 reference

12 December 2020

Fish-oil fatty acid supplementation in active rheumatoid arthritis. A double-blinded, controlled, crossover study

1 reference

12 December 2020

In vitro effects of eicosanoids derived from different 20-carbon fatty acids on T helper type 1 and T helper type 2 cytokine production in human whole-blood cultures

1 reference

12 December 2020

Dietary fat and asthma: is there a connection?

1 reference

12 December 2020

Dietary (n-3) polyunsaturated fatty acids suppress murine lymphoproliferation, interleukin-2 secretion, and the formation of diacylglycerol and ceramide

1 reference

12 December 2020

Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation

1 reference

12 December 2020

10.1111/J.1365-2125.2012.04374.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22765297%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22765297%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

22765297

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22765297%20AND%20SRC:MED&resulttype=core&format=json