Oxidative stress in cardiovascular diseases and obesity: role of p66Shc and protein kinase C. (Q36763396)

16 August 2017

6 references

19 March 2019

24 March 2019

17 June 2019

28 September 2019

20 November 2019

28 November 2019

Oxidative stress in cardiovascular diseases and obesity: role of p66Shc and protein kinase C. (English)

1 reference

16 August 2017

7 references

19 March 2019

24 March 2019

17 June 2019

28 September 2019

20 November 2019

28 November 2019

20 September 2020

cardiovascular disease

7 references

19 March 2019

24 March 2019

17 June 2019

28 September 2019

20 November 2019

28 November 2019

20 September 2020

1 reference

28 September 2019

1 reference

20 November 2019

1 reference

28 November 2019

Elena De Marchi

1

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Mariusz R Wieckowski

object named as

Mariusz R Wieckowski

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4

0 references

Paolo Pinton

object named as

Paolo Pinton

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5

0 references

Federica Baldassari

series ordinal

2

object named as

Federica Baldassari

1 reference

16 August 2017

Angela Bononi

3

1 reference

PMC publication ID

3625561

16 August 2017

language of work or name

1 reference

27 March 2013

7 references

Oxidative medicine and cellular longevity

16 August 2017

19 March 2019

24 March 2019

17 June 2019

28 September 2019

20 November 2019

28 November 2019

8 references

16 August 2017

19 March 2019

24 March 2019

17 June 2019

28 September 2019

20 November 2019

28 November 2019

20 September 2020

2013

1 reference

16 August 2017

564961

1 reference

Creative Commons Attribution 3.0 Unported

16 August 2017

6 references

19 March 2019

24 March 2019

17 June 2019

28 September 2019

20 November 2019

on focus list of Wikimedia project

28 November 2019

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cites work

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Dietary antioxidants: Do they have a role to play in the ongoing fight against abnormal glucose metabolism?

29 September 2017

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29 September 2017

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Evaluating oxidative stress in human cardiovascular disease: methodological aspects and considerations

29 September 2017

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29 September 2017

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Molecular mechanisms of hypertension--reactive oxygen species and antioxidants: a basic science update for the clinician

29 September 2017

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Mitochondria in vascular disease

29 September 2017

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Mitochondrial reactive oxygen species and risk of atherosclerosis

29 September 2017

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Dietary advanced glycation end products and aging

29 September 2017

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Mitochondria-ros crosstalk in the control of cell death and aging

29 September 2017

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N-acetylcysteine reduces markers of differentiation in 3T3-L1 adipocytes

29 September 2017

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p66Shc aging protein in control of fibroblasts cell fate

29 September 2017

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ROS and RNS signaling in heart disorders: could antioxidant treatment be successful?

29 September 2017

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Vitamins C and E: beneficial effects from a mechanistic perspective

29 September 2017

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Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events

29 September 2017

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The Shc locus regulates insulin signaling and adiposity in mammals

29 September 2017

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Cellular metabolic stress: considering how cells respond to nutrient excess.

29 September 2017

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Protein Kinase C Inhibitors in the Treatment of Diabetic Retinopathy. Review

29 September 2017

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Oxidative stress as a mediator of cardiovascular disease

29 September 2017

1 reference

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NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart.

29 September 2017

1 reference

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Mitochondrial ROS generation and its regulation: mechanisms involved in H(2)O(2) signaling

29 September 2017

1 reference

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Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance

29 September 2017

1 reference

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Antioxidants and glucose metabolism disorders

29 September 2017

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29 September 2017

P66Shc signals to age.

1 reference

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Redox control of protein kinase C: cell- and disease-specific aspects

29 September 2017

1 reference

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The emerging role of cardiovascular risk factor-induced mitochondrial dysfunction in atherogenesis

29 September 2017

1 reference

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The Maillard reaction in the human body. The main discoveries and factors that affect glycation

29 September 2017

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Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice

29 September 2017

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p66(Shc) protein, oxidative stress, and cardiovascular complications of diabetes: the missing link.

29 September 2017

1 reference

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Role of NADPH oxidase in atherosclerosis

29 September 2017

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Molecular and biochemical changes of the cardiovascular system due to smoking exposure

29 September 2017

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Mitochondria and vascular pathology.

29 September 2017

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Loss of protein kinase Cbeta function protects mice against diet-induced obesity and development of hepatic steatosis and insulin resistance

29 September 2017

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p66Shc-generated oxidative signal promotes fat accumulation

29 September 2017

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The phagocytes: neutrophils and monocytes

29 September 2017

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The molecular sources of reactive oxygen species in hypertension

29 September 2017

1 reference

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Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies

29 September 2017

1 reference

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p66Shc, oxidative stress and aging: importing a lifespan determinant into mitochondria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Differential recruitment of PKC isoforms in HeLa cells during redox stress

29 September 2017

1 reference

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Diabetes and the impairment of reproductive function: possible role of mitochondria and reactive oxygen species.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

High glucose induces adipogenic differentiation of muscle-derived stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Final common molecular pathways of aging and cardiovascular disease: role of the p66Shc protein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Reduction of fat deposition by combined inhibition of monoamine oxidases and semicarbazide-sensitive amine oxidases in obese Zucker rats

29 September 2017

1 reference

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The road to advanced glycation end products: a mechanistic perspective.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Adipocytokines - novel link between inflammation and vascular function?

29 September 2017

1 reference

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The structure of aquaporins

29 September 2017

1 reference

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Bioenergetics and the formation of mitochondrial reactive oxygen species.

29 September 2017

1 reference

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Role of extracellular superoxide dismutase in hypertension

29 September 2017

1 reference

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Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation

29 September 2017

1 reference

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Fat as an endocrine organ: relationship to the metabolic syndrome.

29 September 2017

1 reference

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NADPH oxidase-derived reactive oxygen species in cardiac pathophysiology

29 September 2017

1 reference

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29 September 2017

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Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation

29 September 2017

1 reference

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Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

29 September 2017

1 reference

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Role of oxidative modifications in atherosclerosis

29 September 2017

1 reference

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Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

29 September 2017

1 reference

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Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Advanced glycation end product cross-linking: pathophysiologic role and therapeutic target in cardiovascular disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet.

29 September 2017

1 reference

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Mechanisms of superoxide production in human blood vessels: relationship to endothelial dysfunction, clinical and genetic risk factors.

29 September 2017

1 reference

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Protein kinase C and lipid-induced insulin resistance in skeletal muscle.

29 September 2017

1 reference

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Exacerbated vein graft arteriosclerosis in protein kinase Cdelta-null mice

29 September 2017

1 reference

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Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC.

29 September 2017

1 reference

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Obesity and the regulation of energy balance

29 September 2017

1 reference

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Evolution of Shc functions from nematode to human

29 September 2017

1 reference

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

29 September 2017

1 reference

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Antioxidants for vascular disease

29 September 2017

1 reference

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

FFA‐Induced Adipocyte Inflammation and Insulin Resistance: Involvement of ER Stress and IKKβ Pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Luteolin inhibits adipogenic differentiation by regulating PPARgamma activation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Involvement of protein kinase C in human skeletal muscle insulin resistance and obesity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Protein kinase C isoforms play differential roles in the regulation of adipocyte differentiation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Characterization of a specific form of protein kinase C overproduced by a C3H 10T1/2 cell line

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Endogenous secretory RAGE in obese women: association with platelet activation and oxidative stress

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

The p66Shc knocked out mice are short lived under natural condition.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Mitochondrial longevity pathways.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

The p66shc Gene Expression in Peripheral Blood Monocytes Is Increased in Patients With Coronary Artery Disease

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Protein tyrosine phosphatase PTPεM negatively regulates PDGF β-receptor signaling induced by high glucose and PDGF in vascular smooth muscle cells

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Effect of pistachio diet on lipid parameters, endothelial function, inflammation, and oxidative status: a prospective study

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Antipsychotic-induced body weight gain: predictors and a systematic categorization of the long-term weight course

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

p66Shc deletion confers vascular protection in advanced atherosclerosis in hypercholesterolemic apolipoprotein E knockout mice

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Nutrition impacts the prevalence of peripheral arterial disease in the United States

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

The implication of obesity on total antioxidant capacity in apparently healthy men and women: the ATTICA study.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Association of anti-obesity activity of N-acetylcysteine with metallothionein-II down-regulation

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

In vivo imaging of oxidative stress in the kidney of diabetic mice and its normalization by angiotensin II type 1 receptor blocker

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Resistance to insulin-mediated glucose disposal as a predictor of cardiovascular disease

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Failure of chronic, high-dose, oral vitamin E treatment to protect the ischemic, reperfused porcine heart

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Cardiac recovery during post-ischemic reperfusion is improved by combination of vitamin E with dihydrolipoic acid

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Oxidative injury to myocardial membrane: direct modulation by endogenous alpha-tocopherol

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625561

Increased ultra weak chemiluminescence emission from rat heart at postischemic reoxygenation: protective role of vitamin E

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2013%2F564961

Protein kinase C deficiency increases fatty acid oxidation and reduces fat storage

21 January 2018

1 reference

12 December 2020

The role of glycation cross-links in diabetic vascular stiffening

1 reference

12 December 2020

Protection of ischemic preconditioning is dependent upon a critical timing sequence of protein kinase C activation

1 reference

12 December 2020

Specific aquaporins facilitate the diffusion of hydrogen peroxide across membranes

1 reference

12 December 2020

Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc

1 reference

12 December 2020

Angiotensin II induces superoxide anion production by mesangial cells

1 reference

12 December 2020

Diabetes Promotes Cardiac Stem Cell Aging and Heart Failure, Which Are Prevented by Deletion of the p66 shc Gene

1 reference

12 December 2020

Atherogenic inflammatory and oxidative stress markers in relation to overweight values in male former athletes

1 reference

12 December 2020

Identifiers

DOI

10.1155/2013/564961

1 reference

16 August 2017

1 reference

PMC publication ID

3625561

16 August 2017

PubMed publication ID

23606925

1 reference

PMC publication ID

3625561