Promise and progress for functional and molecular imaging of response to targeted therapies. (Q36769980)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17385018%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

review article

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title

Promise and progress for functional and molecular imaging of response to targeted therapies (English)

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28 December 2019

2

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28 December 2019

author name string

Renu M Stephen

series ordinal

1

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28 December 2019

publication date

24 March 2007

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28 December 2019

published in

Pharmaceutical Research

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28 December 2019

volume

24

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28 December 2019

issue

6

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28 December 2019

page(s)

1172-1185

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Early detection of treatment response by diffusion-weighted 1H-NMR spectroscopy in a murine tumour in vivo

28 December 2019

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The value of improving the productivity of the drug development process: faster times and better decisions

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FDG-PET and beyond: molecular breast cancer imaging

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Exploiting the PI3K/AKT pathway for cancer drug discovery

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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12 December 2020

Dynamic contrast-enhanced and diffusion MRI show rapid and dramatic changes in tumor microenvironment in response to inhibition of HIF-1alpha using PX-478.

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12 December 2020

Diffusion-weighted magnetic resonance imaging allows noninvasive in vivo monitoring of the effects of combretastatin a-4 phosphate after repeated administration

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12 December 2020

Monitoring early response of experimental brain tumors to therapy using diffusion magnetic resonance imaging

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12 December 2020

Changes in water mobility measured by diffusion MRI predict response of metastatic breast cancer to chemotherapy

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12 December 2020

Functional tumor imaging with dynamic contrast‐enhanced magnetic resonance imaging

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12 December 2020

Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1

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12 December 2020

Do oncologists believe new cancer drugs offer good value?

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12 December 2020

Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors.

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12 December 2020

Impaired angiogenesis, delayed wound healing and retarded tumor growth in perlecan heparan sulfate-deficient mice

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12 December 2020

Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

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12 December 2020

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12 December 2020

Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling

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The price of innovation: new estimates of drug development costs

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12 December 2020

Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway

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12 December 2020

Bevacizumab in combination with fluorouracil and leucovorin: an active regimen for first-line metastatic colorectal cancer

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12 December 2020

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12 December 2020

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12 December 2020

Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

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12 December 2020

The consensus coding sequences of human breast and colorectal cancers

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12 December 2020

Cellular survival: a play in three Akts

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12 December 2020

Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells

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12 December 2020

Dynamic imaging of emerging resistance during cancer therapy

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12 December 2020

Role of 2-[18F]-fluorodeoxyglucose (FDG) positron emission tomography (PET) in the early assessment of response to chemotherapy in metastatic breast cancer patients

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12 December 2020

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12 December 2020

Prognostic value of vascular endothelial growth factor expression in colorectal cancer patients

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12 December 2020

Dynamic contrast-enhanced magnetic resonance imaging in oncology.

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12 December 2020

Targeting HIF-1 for cancer therapy

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12 December 2020

Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha.

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12 December 2020

Causes and effects of heterogeneous perfusion in tumors

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

MRI of the tumor microenvironment.

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12 December 2020

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12 December 2020

Functional diffusion map: a noninvasive MRI biomarker for early stratification of clinical brain tumor response

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12 December 2020

Dual time point 18F-FDG PET imaging detects breast cancer with high sensitivity and correlates well with histologic subtypes.

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12 December 2020

Assessing changes in tumour vascular function using dynamic contrast-enhanced magnetic resonance imaging

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12 December 2020

Inhibition of phosphatidylinositol-3-kinase causes increased sensitivity to radiation through a PKB-dependent mechanism

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12 December 2020

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12 December 2020

Therapeutic efficacy of DTI-015 using diffusion magnetic resonance imaging as an early surrogate marker

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12 December 2020

PTK787/ZK222584, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor, reduces uptake of the contrast agent GdDOTA by murine orthotopic B16/BL6 melanoma tumours and inhibits their growth in vivo

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12 December 2020

Assessment of induced rat mammary tumour response to chemotherapy using the apparent diffusion coefficient of tissue water as determined by diffusion-weighted 1H-NMR spectroscopy in vivo

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12 December 2020

Diffusion-weighted magnetic resonance imaging for monitoring diffusion changes in rectal carcinoma during combined, preoperative chemoradiation: preliminary results of a prospective study

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12 December 2020

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12 December 2020

Biologic correlates of (18)fluorodeoxyglucose uptake in human breast cancer measured by positron emission tomography

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12 December 2020

Metabolite changes in HT-29 xenograft tumors following HIF-1alpha inhibition with PX-478 as studied by MR spectroscopy in vivo and ex vivo

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12 December 2020

Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer a

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12 December 2020

The progress and promise of molecular imaging probes in oncologic drug development

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12 December 2020

Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI.

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12 December 2020

Applications of magnetic resonance in model systems: tumor biology and physiology

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12 December 2020

VEGF as a therapeutic target in cancer

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12 December 2020

Early detection of response to radiation therapy in patients with brain malignancies using conventional and high b-value diffusion-weighted magnetic resonance imaging

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12 December 2020

The protein kinase B/Akt signalling pathway in human malignancy

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12 December 2020

VEGF, FGF2, TGFB1 and TGFBR1 mRNA expression levels correlate with the malignant transformation of the uterine cervix.

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12 December 2020

Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression

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12 December 2020

The balance of VEGF-C and VEGFR-3 mRNA is a predictor of lymph node metastasis in non-small cell lung cancer

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12 December 2020

MRI monitoring of Avastin antiangiogenesis therapy using B22956/1, a new blood pool contrast agent, in an experimental model of human cancer

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12 December 2020

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12 December 2020

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12 December 2020

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

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12 December 2020

Applications of magnetic resonance in model systems: cancer therapeutics

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12 December 2020

Evaluating the efficiency of targeted designs for randomized clinical trials

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12 December 2020

Heterogeneity in the angiogenic response of a BT474 human breast cancer to a novel vascular endothelial growth factor-receptor tyrosine kinase inhibitor: assessment by voxel analysis of dynamic contrast-enhanced MRI.

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12 December 2020

A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Oncology Group study E2200.

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12 December 2020

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

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12 December 2020

Physicochemical and biological evaluation of P792, a rapid-clearance blood-pool agent for magnetic resonance imaging

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12 December 2020

FDG-PET in staging and restaging non-small cell lung cancer after neoadjuvant chemoradiotherapy: correlation with histopathology

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12 December 2020

Vascular endothelial growth factor induces proliferation of breast cancer cells and inhibits the anti-proliferative activity of anti-hormones

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12 December 2020

10.1007/S11095-007-9250-3

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17385018%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

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