Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis (Q36777632)

16 August 2017

Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis (English)

1 reference

16 August 2017

Murugavel Ponnusamy

4

0 references

author name string

Yanli Yan

1

1 reference

16 August 2017

Li Ma

2

1 reference

16 August 2017

Xiaoxu Zhou

3

1 reference

16 August 2017

Jinhua Tang

5

1 reference

16 August 2017

Michelle A Zhuang

6

1 reference

16 August 2017

Evelyn Tolbert

7

1 reference

16 August 2017

Georgia Bayliss

8

1 reference

16 August 2017

Jianwen Bai

9

1 reference

16 August 2017

Shougang Zhuang

10

1 reference

16 August 2017

language of work or name

English

0 references

publication date

7 October 2015

1 reference

16 August 2017

1 reference

16 August 2017

89

1 reference

16 August 2017

1

1 reference

16 August 2017

68-81

1 reference

https://scigraph.springernature.com/pub.10.1038/ki.2015.293

16 August 2017

0 references

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Role of the TGF-β/BMP-7/Smad pathways in renal diseases

29 September 2017

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29 September 2017

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Genetic or pharmacologic blockade of EGFR inhibits renal fibrosis.

29 September 2017

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EGFR signaling promotes TGFβ-dependent renal fibrosis

29 September 2017

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Cellular and molecular mechanisms of renal fibrosis

29 September 2017

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Diverse roles of TGF-β/Smads in renal fibrosis and inflammation

29 September 2017

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Suramin inhibits renal fibrosis in chronic kidney disease.

29 September 2017

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Current status of SRC inhibitors in solid tumor malignancies

29 September 2017

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A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy

29 September 2017

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Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

29 September 2017

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EGF receptor activation by GPCRs: an universal pathway reveals different versions

29 September 2017

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Src inhibition ameliorates polycystic kidney disease

29 September 2017

1 reference

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Phosphorylation of TNF-alpha converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation.

29 September 2017

1 reference

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c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells

29 September 2017

1 reference

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Transactivating agonists of the EGF receptor require Tyr 845 phosphorylation for induction of DNA synthesis

29 September 2017

1 reference

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Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growth

29 September 2017

1 reference

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c-Src-mediated phosphorylation of TRIP6 regulates its function in lysophosphatidic acid-induced cell migration

29 September 2017

1 reference

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Cell proliferation and cell cycle control: a mini review

29 September 2017

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c-Src and cooperating partners in human cancer

29 September 2017

1 reference

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Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways

29 September 2017

1 reference

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Transforming growth factor-beta1-dependent urokinase up-regulation and promotion of invasion are involved in Src-MAPK-dependent signaling in human ovarian cancer cells

29 September 2017

1 reference

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c-Src regulation of fibroblast growth factor-induced proliferation in murine embryonic fibroblasts

29 September 2017

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Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation

29 September 2017

1 reference

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Proximal events in signaling by plasma membrane estrogen receptors

29 September 2017

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Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer

29 September 2017

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Targeted expression of a dominant-negative EGF-R in the kidney reduces tubulo-interstitial lesions after renal injury

29 September 2017

1 reference

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Role of c-Src tyrosine kinase in EGF-induced mitogenesis.

29 September 2017

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Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

29 September 2017

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Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

29 September 2017

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Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

29 September 2017

1 reference

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Regulation of receptor tyrosine kinase ligand processing

29 September 2017

1 reference

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Activation of Src mediates PDGF-induced Smad1 phosphorylation and contributes to the progression of glomerulosclerosis in glomerulonephritis.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4824676

Inhibition of Src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4824676

Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4824676

Involvement of c-Src/STAT3 signal in EGF-induced proliferation of rat spermatogonial stem cells.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4824676

Src kinases in systemic sclerosis: central roles in fibroblast activation and in skin fibrosis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4824676

Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4824676

H2O2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cells.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4824676

Rapamycin and chronic kidney disease: beyond the inhibition of inflammation

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26444028

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26444028

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/KI.2015.293

1 reference

16 August 2017

1 reference

16 August 2017

1 reference