Stability and structural recovery of the tetramerization domain of p53-R337H mutant induced by a designed templating ligand (Q36954828)

17 August 2017

Stability and structural recovery of the tetramerization domain of p53-R337H mutant induced by a designed templating ligand (English)

1 reference

17 August 2017

Margarita Menéndez

4

0 references

Carles Bo

object named as

Carles Bo

5

0 references

Ernest Giralt i Lledó

object named as

Ernest Giralt

6

0 references

author name string

Susana Gordo

1

1 reference

17 August 2017

Vera Martos

2

1 reference

17 August 2017

Eva Santos

3

1 reference

17 August 2017

Javier de Mendoza

7

1 reference

17 August 2017

language of work or name

English

0 references

publication date

21 October 2008

1 reference

17 August 2017

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

17 August 2017

105

1 reference

17 August 2017

43

1 reference

17 August 2017

16426-16431

1 reference

Amine-guanidine switch: a promising approach to improve DNA binding and antiproliferative activities

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Structure-function-rescue: the diverse nature of common p53 cancer mutants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Strategies to search and design stabilizers of protein-protein interactions: a feasibility study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Unfolding, aggregation, and amyloid formation by the tetramerization domain from mutant p53 associated with lung cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Targeting protein-protein interactions for cancer therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

GROMACS: fast, flexible, and free

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Protein-protein interactions in human disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Protein oligomerization: how and why.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Strategies for targeting protein-protein interactions with synthetic agents.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Protein production by auto-induction in high density shaking cultures

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Characterization of protein-protein interactions by isothermal titration calorimetry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Therapeutic approaches to protein-misfolding diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Thermodynamic studies of lectin-carbohydrate interactions by isothermal titration calorimetry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

The role of tetramerization in p53 function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Lethality and centrality in protein networks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Crystallization and structure solution of p53 (residues 326-356) by molecular replacement using an NMR model as template

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

p53, the cellular gatekeeper for growth and division

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Solution structure of the tetrameric minimum transforming domain of p53

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Thermodynamics of the binding of L-arabinose and of D-galactose to the L-arabinose-binding protein of Escherichia coli

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Study of strong to ultratight protein interactions using differential scanning calorimetry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Nine hydrophobic side chains are key determinants of the thermodynamic stability and oligomerization status of tumour suppressor p53 tetramerization domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Nuclear magnetic resonance line-shape analysis and determination of exchange rates.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Ligand-induced biphasic protein denaturation.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

The TP53 mutation, R337H, is associated with Li-Fraumeni and Li-Fraumeni-like syndromes in Brazilian families.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Penetrance of adrenocortical tumours associated with the germline TP53 R337H mutation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Auto-induction medium for the production of [U-15N]- and [U-13C, U-15N]-labeled proteins for NMR screening and structure determination

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

NMR-based characterization of phenothiazines as a RNA binding scaffold

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

A tetraguanidinium ligand binds to the surface of the tetramerization domain of protein P53.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Delineation of the allosteric mechanism of a cytidylyltransferase exhibiting negative cooperativity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575436

Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand Architecture

4 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0805658105

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0805658105

Molecular dynamics with coupling to an external bath

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0805658105

Temperature dependence of ligand–protein complex formation as reflected by saturation transfer difference NMR experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0805658105

Mechanism of folding and assembly of a small tetrameric protein domain from tumor suppressor p53

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18940924

12 December 2020

inferred from PubMed ID database lookup

Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18940924

12 December 2020

inferred from PubMed ID database lookup

Thermodynamic analysis of the structural stability of the tetrameric oligomerization domain of p53 tumor suppressor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18940924

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0805658105

1 reference

17 August 2017

0 references

1 reference

17 August 2017

PubMed publication ID

18940924

1 reference