Superoxide and derived reactive oxygen species in the regulation of hypoxia-inducible factors. (Q36999104)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998067%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

review article

1 reference

title

Superoxide and derived reactive oxygen species in the regulation of hypoxia-inducible factors (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998067%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

main subject

hypoxia

0 references

reactive oxygen species

1 reference

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998067%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1

Agnes Görlach

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998067%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

language of work or name

English

0 references

publication date

1 January 2007

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998067%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

published in

Methods in Enzymology

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10 January 2020

volume

435

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10 January 2020

page(s)

421-446

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998067%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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Redox-sensitive regulation of the HIF pathway under non-hypoxic conditions in pulmonary artery smooth muscle cells

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NOX5 variants are functionally active in endothelial cells

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Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical

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NAD(P)H oxidases regulate HIF-2alpha protein expression.

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Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1alpha

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NADPH oxidases: not just for leukocytes anymore!

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7 January 2021

Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site

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Selenium-dependent enzymes in endothelial cell function

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Mitochondrial membrane potential and hydroethidine-monitored superoxide generation in cultured cerebellar granule cells.

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Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

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Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

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PTPs versus PTKs: the redox side of the coin

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Production of extracellular superoxide by human lymphoblast cell lines: comparison of electron spin resonance techniques and cytochrome C reduction assay

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The expression of the NADPH oxidase subunit p22phox is regulated by a redox-sensitive pathway in endothelial cells

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Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite

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Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

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7 January 2021

Reactive oxygen species and signal transduction

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Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB.

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5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide: a new efficient phosphorylated nitrone for the in vitro and in vivo spin trapping of oxygen-centered radicals

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Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells

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Atrial natriuretic peptide induces mitogen-activated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxidase/Nox2-activation

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7 January 2021

Arsenite induces HIF-1a and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells

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7 January 2021

Vanadate-induced expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species

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7 January 2021

p38 signaling-mediated hypoxia-inducible factor 1 alpha and vascular endothelial growth factor induction by Cr(VI) in DU145 human prostate carcinoma cells

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JunD reduces tumor angiogenesis by protecting cells from oxidative stress

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Redox signaling through NADPH oxidases: involvement in vascular proliferation and coagulation

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Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions

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Photometric characteristics of haem proteins in erythropoietin-producing hepatoma cells (HepG2).

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Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase

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Novel NAD(P)H oxidases in the cardiovascular system

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Activation and assembly of the NADPH oxidase: a structural perspective

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Expression of hypoxia-inducible factor-1 in the cochlea of newborn rats.

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Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells.

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7 January 2021

Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: suppression of HIF-mediated gene expression by HIF-3alpha

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7 January 2021

Hypoxia rapidly activates HIF-3alpha mRNA expression

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7 January 2021

Dihydrorhodamine 123: a fluorescent probe for superoxide generation?

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Insights into the redox control of blood coagulation: role of vascular NADPH oxidase-derived reactive oxygen species in the thrombogenic cycle

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Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

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Induction of hypoxia-inducible factor 1 activity by muscarinic acetylcholine receptor signaling

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Cloning of a Factor Required for Activity of the Ah (Dioxin) Receptor

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Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

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7 January 2021

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

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7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

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7 January 2021

Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

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Increased superoxide anion production by immunologically activated and chemically elicited macrophages

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The VHL tumour-suppressor gene paradigm

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7 January 2021

Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

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The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

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Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes

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Perivenous expression of the mRNA of the three hypoxia-inducible factor alpha-subunits, HIF1alpha, HIF2alpha and HIF3alpha, in rat liver

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Stabilization of hypoxia-inducible factor-1alpha is involved in the hypoxic stimuli-induced expression of vascular endothelial growth factor in osteoblastic cells

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Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor-1alpha stabilization

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7 January 2021

Peroxynitrite-mediated oxidation of dihydrorhodamine 123

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NOX enzymes and the biology of reactive oxygen

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

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7 January 2021

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

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Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau

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Suppression of the dual-specificity phosphatase MKP-1 enhances HIF-1 trans-activation and increases expression of EPO.

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Reactive oxygen species regulate epidermal growth factor-induced vascular endothelial growth factor and hypoxia-inducible factor-1α expression through activation of AKT and P70S6K1 in human ovarian cancer cells

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7 January 2021

A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression

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7 January 2021

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

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Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma

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7 January 2021

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

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7 January 2021

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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7 January 2021

Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803

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7 January 2021

Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

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7 January 2021

Detection of reactive oxygen and reactive nitrogen species in skeletal muscle

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7 January 2021

Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors

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7 January 2021

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

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7 January 2021

Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms

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7 January 2021

Selective cardiorespiratory and catecholaminergic areas express the hypoxia-inducible factor-1alpha (HIF-1alpha) under in vivo hypoxia in rat brainstem

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7 January 2021

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

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7 January 2021

Normoxic induction of the hypoxic-inducible factor-1 alpha by interleukin-1 beta involves the extracellular signal-regulated kinase 1/2 pathway in normal human cytotrophoblast cells

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7 January 2021

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

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7 January 2021

Selective fluorescent imaging of superoxide in vivo using ethidium-based probes

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7 January 2021

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

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7 January 2021

Regulation of the hypoxia-inducible factor 1alpha by the inflammatory mediators nitric oxide and tumor necrosis factor-alpha in contrast to desferroxamine and phenylarsine oxide

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7 January 2021

Endoplasmic reticulum/cytosolic localization of von Hippel-Lindau gene products is mediated by a 64-amino acid region

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7 January 2021

Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1.

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7 January 2021

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

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7 January 2021

Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1alpha (HIF-1alpha) accumulation via redox-dependent mechanisms

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7 January 2021

MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF.

1 reference

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7 January 2021

Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway.

1 reference

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7 January 2021

Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway

1 reference

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7 January 2021

Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells

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7 January 2021

Hepatocyte growth factor-activated NF-kappaB regulates HIF-1 activity and ODC expression, implicated in survival, differently in different carcinoma cell lines.

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7 January 2021

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

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7 January 2021

Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations

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7 January 2021

Interleukin 1 induces hypoxia-inducible factor 1 in human gingival and synovial fibroblasts

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7 January 2021

Redox redux: revisiting PTPs and the control of cell signaling

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7 January 2021

Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

1 reference

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7 January 2021

Purification and characterization of hypoxia-inducible factor 1

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7 January 2021

Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1.

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7 January 2021

Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1.

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7 January 2021

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

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7 January 2021

Ras induction of superoxide activates ERK-dependent angiogenic transcription factor HIF-1alpha and VEGF-A expression in shock wave-stimulated osteoblasts

1 reference

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7 January 2021

Nitric oxide and reactive oxygen species exert opposing effects on the stability of hypoxia-inducible factor-1alpha (HIF-1alpha) in explants of human pial arteries

1 reference

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7 January 2021

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

1 reference

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7 January 2021

Uptake of fluorescent dyes associated with the functional expression of the cystic fibrosis transmembrane conductance regulator in epithelial cells

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7 January 2021

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Extracellular superoxide dismutase functions as a major repressor of hypoxia-induced erythropoietin gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Functional integrity of nuclear factor kappaB, phosphatidylinositol 3'-kinase, and mitogen-activated protein kinase signaling allows tumor necrosis factor alpha-evoked Bcl-2 expression to provoke internal ribosome entry site-dependent translation of

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5' enhancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Role of nitric oxide in the regulation of HIF-1alpha expression during hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

A gp91phox Containing NADPH Oxidase Selectively Expressed in Endothelial Cells Is a Major Source of Oxygen Radical Generation in the Arterial Wall

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Persistent HIF-1alpha activation in gut ischemia/reperfusion injury: potential role of bacteria and lipopolysaccharide.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Regulation of hypoxia-inducible factor-1alpha by nitric oxide through mitochondria-dependent and -independent pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1alpha in cancer: role of free radical formation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021

Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935022-2

7 January 2021