Natural antioxidants in Alzheimer's disease (Q37016092)

17 August 2017

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title

Natural antioxidants in Alzheimer's disease (English)

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17 August 2017

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3

D Allan Butterfield

1 reference

17 August 2017

Albena Dinkova-Kostova

7

object named as

Albena T Dinkova Kostova

1 reference

17 August 2017

Cesare Mancuso

1

1 reference

17 August 2017

Timothy E Bates

2

1 reference

17 August 2017

Stella Calafato

4

1 reference

17 August 2017

Carolin Cornelius

5

1 reference

17 August 2017

Antonino De Lorenzo

6

1 reference

17 August 2017

Vittorio Calabrese

8

1 reference

17 August 2017

language of work or name

English

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publication date

1 December 2007

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Expert Opinion on Investigational Drugs

17 August 2017

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17 August 2017

16

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17 August 2017

12

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17 August 2017

1921-1931

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Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment

17 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Tracking Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Cholinergic function and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

The substantia innominata in Alzheimer's disease: an histochemical and biochemical study of cholinergic marker enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Effective pharmacologic management of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

NSAIDs and Alzheimer disease: epidemiological, animal model and clinical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Neuropathology of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

The free radical antioxidant vitamin E protects cortical synaptosomal membranes from amyloid beta-peptide(25-35) toxicity but not from hydroxynonenal toxicity: relevance to the free radical hypothesis of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Free radical damage, iron, and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Beta-amyloid peptide potentiates inflammatory responses induced by lipopolysaccharide, interferon -gamma and 'advanced glycation endproducts' in a murine microglia cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Pathways of inflammatory activation in Alzheimer's disease: potential targets for disease modifying drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Brain energy metabolizing enzymes in Alzheimer's disease: alpha-ketoglutarate dehydrogenase complex and cytochrome oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Mitochondrial aging and dysfunction in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Evidence of increased oxidative damage in subjects with mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: implications for the role of nitration in the progression of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Aberrant expression of nNOS in pyramidal neurons in Alzheimer's disease is highly co-localized with p21ras and p16INK4a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Elevated expression of p21ras is an early event in Alzheimer's disease and precedes neurofibrillary degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Metabolism and bioavailability of trans-resveratrol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Therapeutic potential of resveratrol: the in vivo evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

High absorption but very low bioavailability of oral resveratrol in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Absorption of trans-resveratrol in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Transport of resveratrol, a cancer chemopreventive agent, to cellular targets: plasmatic protein binding and cell uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Herbal bioactivation: the good, the bad and the ugly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Potent induction of cellular antioxidants and phase 2 enzymes by resveratrol in cardiomyocytes: protection against oxidative and electrophilic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Inhibition of cancer growth by resveratrol is related to its low bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Resveratrol--a boon for treating Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Neuronal protection by sirtuins in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Redox regulation of heat shock protein expression by signaling involving nitric oxide and carbon monoxide: relevance to brain aging, neurodegenerative disorders, and longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Bilirubin: an endogenous scavenger of nitric oxide and reactive nitrogen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Heme oxygenase and its products in the nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Antioxidant activities of bile pigments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Potential mechanism by which resveratrol, a red wine constituent, protects neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Regulation of inflammation and redox signaling by dietary polyphenols

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Cytotoxic effect of curcumin on Giardia lamblia trophozoites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Curcumin: the story so far.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Recent studies on the biofunctions and biotransformations of curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Differential and Special Properties of the Major Human UGT1-encoded Gastrointestinal UDP-glucuronosyltransferases Enhance Potential to Control Chemical Uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Apolipoprotein E polymorphism and Alzheimer disease: The Indo-US Cross-National Dementia Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Modulation of transcription factors by curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

How curcumin works preferentially with water soluble antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Nrf2 as a novel molecular target for chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Phenolic Michael reaction acceptors: combined direct and indirect antioxidant defenses against electrophiles and oxidants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: the indirect antioxidant effects of sulforaphane

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Pharmacokinetics of L-carnitine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Effect of development and nutritional state on the uptake, metabolism and release of free and acetyl-L-carnitine by the rodent small intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Pharmacokinetics of IV and oral acetyl-L-carnitine in a multiple dose regimen in patients with senile dementia of Alzheimer type.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

"Brain-specific" nutrients: a memory cure?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Double-blind, placebo controlled study of acetyl-l-carnitine in patients with Alzheimer's dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Long-term acetyl-L-carnitine treatment in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

A 1-year controlled trial of acetyl-l-carnitine in early-onset AD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

Advanced Maillard Reaction End Products, Free Radicals, and Protein Oxidation in Alzheimer's Diseasea

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.12.1921

10.1517/13543784.16.12.1921

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference