APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease. (Q37078850)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648430%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648430%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

0 references

0 references

1 reference

2

1 reference

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29 February 2020

Laura Martínez

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648430%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

José C Fernández-Checa

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648430%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Anna Colell

5

1 reference

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29 February 2020

author name string

Elisabet Barbero-Camps

1

1 reference

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29 February 2020

publication date

6 May 2013

1 reference

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29 February 2020

published in

Human Molecular Genetics

1 reference

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29 February 2020

volume

22

1 reference

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29 February 2020

issue

17

1 reference

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29 February 2020

page(s)

3460-3476

1 reference

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describes a project that uses

29 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3736868/fullTextXML

inferred from PubMed Central ID database lookup

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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27 June 2018

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27 June 2018

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27 June 2018

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Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease

27 June 2018

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27 June 2018

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Effects of the superoxide dismutase/catalase mimetic EUK-207 in a mouse model of Alzheimer's disease: protection against and interruption of progression of amyloid and tau pathology and cognitive decline

4 September 2018

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Dietary cholesterol and its effect on tau protein: a study in apolipoprotein E-deficient and P301L human tau mice.

4 September 2018

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Aβ Oligomers Cause Localized Ca2+Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

4 September 2018

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Increased membrane cholesterol might render mature hippocampal neurons more susceptible to beta-amyloid-induced calpain activation and tau toxicity

4 September 2018

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The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development

4 September 2018

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The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy.

4 September 2018

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4 September 2018

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High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice.

4 September 2018

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Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin

4 September 2018

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Lipids as modulators of proteolytic activity of BACE: involvement of cholesterol, glycosphingolipids, and anionic phospholipids in vitro

4 September 2018

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Altered cholesterol metabolism in Niemann-Pick type C1 mouse brains affects mitochondrial function

4 September 2018

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Double dissociation between the effects of peri-postrhinal cortex and hippocampal lesions on tests of object recognition and spatial memory: heterogeneity of function within the temporal lobe.

4 September 2018

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Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice.

4 September 2018

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Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice.

4 September 2018

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Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease

4 September 2018

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Cholesterol storage and tau pathology in Niemann–Pick type C disease in the brain

4 September 2018

1 reference

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Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model.

4 September 2018

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Tangle-bearing neurons contain more free cholesterol than adjacent tangle-free neurons.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736868

The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease

4 September 2018

1 reference

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Relative roles of plaques and tangles in the dementia of Alzheimer's disease: correlations using three sets of neuropathological criteria.

4 September 2018

1 reference

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Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

4 September 2018

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12 December 2020

Determination of free, total, and esterified cholesterol by high-performance liquid chromatography

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12 December 2020

Neurofibrillary tangles in Niemann-Pick disease type C

1 reference

12 December 2020

Pitavastatin decreases tau levels via the inactivation of Rho/ROCK

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDT201

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648430%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648430%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

23648430

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648430%20AND%20SRC:MED&resulttype=core&format=json