T cells in the pathogenesis of type 1 diabetes (Q37150506)

18 August 2017

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title

T cells in the pathogenesis of type 1 diabetes (English)

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18 August 2017

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Roberto Mallone

1

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Peter M van Endert

object named as

Peter van Endert

series ordinal

2

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publication date

1 April 2008

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18 August 2017

Current diabetes report

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18 August 2017

8

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18 August 2017

101-106

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18 August 2017

2

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https://scigraph.springernature.com/pub.10.1007/s11892-008-0019-9

18 August 2017

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cites work

Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice

1 reference

https://api.crossref.org/works/10.1007%2FS11892-008-0019-9

Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-008-0019-9

Transgenic expression of dominant-negative Fas-associated death domain protein in beta cells protects against Fas ligand-induced apoptosis and reduces spontaneous diabetes in nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-008-0019-9

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-008-0019-9

Immunization of HLA class I transgenic mice identifies autoantigenic epitopes eliciting dominant responses in type 1 diabetes patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-008-0019-9

Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies

21 January 2018

1 reference

12 December 2020

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

1 reference

12 December 2020

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

1 reference

12 December 2020

Effects of insulin in relatives of patients with type 1 diabetes mellitus

1 reference

12 December 2020

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

1 reference

12 December 2020

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

1 reference

12 December 2020

Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

1 reference

12 December 2020

Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide

1 reference

12 December 2020

Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes.

1 reference

12 December 2020

CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes

1 reference

12 December 2020

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

1 reference

12 December 2020

Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions

1 reference

12 December 2020

Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives

1 reference

12 December 2020

CD4 cells can be more efficient at tumor rejection than CD8 cells

1 reference

12 December 2020

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

1 reference

12 December 2020

Development of type 1 diabetes despite severe hereditary B-cell deficiency

1 reference

12 December 2020

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

1 reference

12 December 2020

Analysis of T-Cell Assays to Measure Autoimmune Responses in Subjects With Type 1 Diabetes

1 reference

12 December 2020

Evidence that beta cell death in the nonobese diabetic mouse is Fas independent

1 reference

12 December 2020

Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity

1 reference

12 December 2020

CD8+ T cells in autoimmunity

1 reference

12 December 2020

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

1 reference

12 December 2020

IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes

1 reference

12 December 2020

Targeted disruption of the IA-2beta gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice.

1 reference

12 December 2020

Induction of a non-encephalitogenic type 2 T helper-cell autoimmune responsein multiple sclerosis after administration of an altered peptide ligand ina placebo-controlled, randomized phase II trial

1 reference

12 December 2020

GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65.

1 reference

12 December 2020

Evidence for in vivo primed and expanded autoreactive T cells as a specific feature of patients with type 1 diabetes

1 reference

12 December 2020

Identification of naturally processed HLA-A2--restricted proinsulin epitopes by reverse immunology.

1 reference

12 December 2020

The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus

1 reference

12 December 2020

The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice

1 reference

12 December 2020

Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes

1 reference

12 December 2020

Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent

1 reference

12 December 2020

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

1 reference

12 December 2020

Diabetogenic T-cell clones

1 reference

12 December 2020

Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta-cells in nonobese diabetic mice.

1 reference

12 December 2020

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

1 reference

12 December 2020

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

1 reference

12 December 2020

Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase

1 reference

12 December 2020

In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis

1 reference

12 December 2020

Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice

1 reference

12 December 2020

Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse

1 reference

12 December 2020

Mouse islet cell lysis mediated by interleukin-1-induced Fas.

1 reference

12 December 2020

Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients

1 reference

12 December 2020

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

1 reference

12 December 2020

10.1007/S11892-008-0019-9

Identifiers

DOI

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18 August 2017

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PubMed ID

18445351