Recent insights in islet amyloid polypeptide-induced membrane disruption and its role in beta-cell death in type 2 diabetes mellitus (Q37165186)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483616%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

review article

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26 August 2020

27 January 2021

4 February 2021

Recent insights in islet amyloid polypeptide-induced membrane disruption and its role in beta-cell death in type 2 diabetes mellitus (English)

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7 January 2020

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4 February 2021

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human digestive system

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macromolecular substances

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16 November 2019

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26 August 2020

insulin-secreting cells

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27 January 2021

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7 January 2020

Maarten F.M. Engel

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4

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7 January 2020

author name string

J Antoinette Killian

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2

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7 January 2020

Jo W M Höppener

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3

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7 January 2020

language of work or name

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1 January 2008

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Experimental Diabetes Research

7 January 2020

published in

12 references

13 March 2019

14 March 2019

24 March 2019

5 August 2019

7 October 2019

10 October 2019

12 October 2019

16 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483616%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

26 August 2020

27 January 2021

4 February 2021

2008

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7 January 2020

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Creative Commons Attribution 3.0 Unported

7 January 2020

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13 March 2019

14 March 2019

24 March 2019

5 August 2019

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4 February 2021

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cites work

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6 September 2017

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6 September 2017

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Intracellular amyloidogenesis by human islet amyloid polypeptide induces apoptosis in COS-1 cells

6 September 2017

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Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model

6 September 2017

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Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

6 September 2017

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Human islet amyloid polypeptide expression in COS-1 cells. A model of intracellular amyloidogenesis

6 September 2017

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Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

6 September 2017

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Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

6 September 2017

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Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

6 September 2017

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High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes

6 September 2017

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Two novel immortal pancreatic beta-cell lines expressing and secreting human islet amyloid polypeptide do not spontaneously develop islet amyloid.

14 September 2017

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28 September 2017

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Pancreatic beta-cell granule peptides form heteromolecular complexes which inhibit islet amyloid polypeptide fibril formation

27 June 2018

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Direct measurement of islet amyloid polypeptide fibrillogenesis by mass spectrometry

27 June 2018

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27 June 2018

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27 June 2018

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27 June 2018

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Synergistic action of polyanionic and non-polar cofactors in fibrillation of human islet amyloid polypeptide.

27 June 2018

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The role of His-18 in amyloid formation by human islet amyloid polypeptide

3 September 2018

1 reference

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Lipid membranes modulate the structure of islet amyloid polypeptide.

3 September 2018

1 reference

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Binding of endostatin to phosphatidylserine-containing membranes and formation of amyloid-like fibers.

3 September 2018

1 reference

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Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death.

3 September 2018

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Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

3 September 2018

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Identifying structural features of fibrillar islet amyloid polypeptide using site-directed spin labeling

3 September 2018

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Phospholipid catalysis of diabetic amyloid assembly

3 September 2018

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Formation of amyloid fibers triggered by phosphatidylserine-containing membranes

3 September 2018

1 reference

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Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation

3 September 2018

1 reference

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Identification of minimal peptide sequences in the (8-20) domain of human islet amyloid polypeptide involved in fibrillogenesis.

3 September 2018

1 reference

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Inhibition of amyloid fibril formation of human amylin by N-alkylated amino acid and alpha-hydroxy acid residue containing peptides

3 September 2018

1 reference

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Islet amyloid: phase partitioning and secondary nucleation are central to the mechanism of fibrillogenesis.

3 September 2018

1 reference

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Inhibitors can arrest the membrane activity of human islet amyloid polypeptide independently of amyloid formation

3 September 2018

1 reference

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Analysis of the minimal amyloid-forming fragment of the islet amyloid polypeptide. An experimental support for the key role of the phenylalanine residue in amyloid formation

3 September 2018

1 reference

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Islet amyloid polypeptide: identification of long-range contacts and local order on the fibrillogenesis pathway

3 September 2018

1 reference

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Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis

3 September 2018

1 reference

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Ultrastructural evidence that apoptosis is the mechanism by which human amylin evokes death in RINm5F pancreatic islet beta-cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377315

Effects of sequential proline substitutions on amyloid formation by human amylin20-29.

3 September 2018

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Conserved and Cooperative Assembly of Membrane-Bound α-Helical States of Islet Amyloid Polypeptide†

3 September 2018

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Crossref

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Amyloid Fibril Formation from Full-Length and Fragments of Amylin

21 January 2018

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12 December 2020

Islet amyloid polypeptide inserts into phospholipid monolayers as monomer

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12 December 2020

Molecular mapping of the recognition interface between the islet amyloid polypeptide and insulin

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12 December 2020

Aromatic Interactions Are Not Required for Amyloid Fibril Formation by Islet Amyloid Polypeptide but Do Influence the Rate of Fibril Formation and Fibril Morphology†

1 reference

12 December 2020

Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes

1 reference

12 December 2020

Identification and characterization of a novel molecular-recognition and self-assembly domain within the islet amyloid polypeptide

1 reference

12 December 2020

The Human Islet Amyloid Polypeptide Forms Transient Membrane-Active Prefibrillar Assemblies†

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12 December 2020

Polymorphic Fibrillar Assembly of Human Amylin

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12 December 2020

Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro

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12 December 2020

Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers

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12 December 2020

Neutron diffraction reveals sequence-specific membrane insertion of pre-fibrillar islet amyloid polypeptide and inhibition by rifampicin

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12 December 2020

Fine structure of islets of Langerhans in insular amyloidosis

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12 December 2020

Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes

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12 December 2020

Sequence divergence in a specific region of islet amyloid polypeptide (IAPP) explains differences in islet amyloid formation between species

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12 December 2020

Promotion of beta-structure by interaction of diabetes associated polypeptide (amylin) with phosphatidylcholine

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12 December 2020

Lipid composition of glucose-stimulated pancreatic islets and insulin-secreting tumor cells

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12 December 2020

Effect of pH and insulin on fibrillogenesis of islet amyloid polypeptide in vitro

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12 December 2020

Pore formation by the cytotoxic islet amyloid peptide amylin

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12 December 2020

Effects of beta cell granule components on human islet amyloid polypeptide fibril formation

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12 December 2020

A Single-Point Mutation Converts the Highly Amyloidogenic Human Islet Amyloid Polypeptide into a Potent Fibrillization Inhibitor

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12 December 2020

Identifiers

DOI

10.1155/2008/421287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483616%20AND%20SRC:MED&resulttype=core&format=json

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7 January 2020

Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18483616%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference