Regulation of ABC membrane transporters in glial cells: relevance to the pharmacotherapy of brain HIV-1 infection (Q37224797)

19 August 2017

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title

Regulation of ABC membrane transporters in glial cells: relevance to the pharmacotherapy of brain HIV-1 infection (English)

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19 August 2017

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Patrick T Ronaldson

1

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19 August 2017

Yuri Persidsky

series ordinal

2

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19 August 2017

Reina Bendayan

series ordinal

3

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19 August 2017

language of work or name

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1 December 2008

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19 August 2017

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19 August 2017

56

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19 August 2017

1711-1735

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19 August 2017

16

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P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain

19 August 2017

1 reference

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Neurocognitive dysfunction predicts postmortem findings of HIV encephalitis

21 January 2018

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Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis

21 January 2018

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Early viral brain invasion in iatrogenic human immunodeficiency virus infection

21 January 2018

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Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface

21 January 2018

1 reference

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Altered P-glycoprotein expression in AIDS patients with HIV encephalitis.

21 January 2018

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Neurotrophic and neuroprotective actions of estrogens and their therapeutic implications

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Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis

21 January 2018

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HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells

21 January 2018

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Functional synergy between CD40 ligand and HIV-1 Tat contributes to inflammation: implications in HIV type 1 dementia.

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TLR2 signaling renders quiescent naive and memory CD4+ T cells more susceptible to productive infection with X4 and R5 HIV-type 1.

21 January 2018

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HIV-1 infection of subcortical astrocytes in the pediatric central nervous system.

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Higher frequency of dementia in older HIV-1 individuals: the Hawaii Aging with HIV-1 Cohort

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Expression of P-glycoprotein in human cerebral cortex microvessels

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The role of breast cancer resistance protein (BCRP/ABCG2) in cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors

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Astrocyte activation and dysfunction and neuron death by HIV-1 Tat expression in astrocytes

21 January 2018

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Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41.

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7 January 2021

Updated research nosology for HIV-associated neurocognitive disorders

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Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice

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Localization of P-glycoprotein at the nuclear envelope of rat brain cells

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Glial cells express multiple ATP binding cassette proteins which are involved in ATP release

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7 January 2021

Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier.

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7 January 2021

Functional expression and localization of P-glycoprotein at the blood brain barrier

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7 January 2021

In situ localization of P-glycoprotein (ABCB1) in human and rat brain

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Cytokines influence mRNA expression of cytochrome P450 3A4 and MDRI in intestinal cells

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CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity

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Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures

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7 January 2021

Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels

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7 January 2021

A family of drug transporters: the multidrug resistance-associated proteins.

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7 January 2021

Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis.

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Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide

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Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs

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7 January 2021

Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide.

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7 January 2021

Neuropathology of Human Immunodeficiency Virus Infection

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7 January 2021

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes

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Isolation and long-term culture of primary ocular human immunodeficiency virus type 1 isolates in primary astrocytes

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A randomized, placebo-controlled trial of rosiglitazone for HIV-related lipoatrophy.

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7 January 2021

P-glycoprotein in the placenta: expression, localization, regulation and function.

1 reference

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7 January 2021

The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on p-glycoprotein expression in peripheral blood mononuclear cells in vitro

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7 January 2021

Molecular programming of endothelin-1 in HIV-infected brain: role of Tat in up-regulation of ET-1 and its inhibition by statins

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7 January 2021

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

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7 January 2021

Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae

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7 January 2021

Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats

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7 January 2021

Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier.

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7 January 2021

How MAP kinases are regulated

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7 January 2021

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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7 January 2021

Change in coreceptor use correlates with disease progression in HIV-1--infected individuals

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7 January 2021

17beta-estradiol reduces neuronal apoptosis induced by HIV-1 gp120 in the neocortex of rat.

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7 January 2021

Prevalence and pattern of neuropsychological impairment in human immunodeficiency virus-infected/acquired immunodeficiency syndrome (HIV/AIDS) patients across pre- and post-highly active antiretroviral therapy eras: a combined study of two cohorts.

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7 January 2021

Variable benefit in neuropsychological function in HIV-infected HAART-treated patients.

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7 January 2021

Multidrug resistance-associated proteins: expression and function in the central nervous system

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https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Multidrug resistance protein 1-mediated transport of saquinavir by microglia

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7 January 2021

Multidrug resistance protein (MRP) 4- and MRP 5-mediated efflux of 9-(2-phosphonylmethoxyethyl)adenine by microglia

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7 January 2021

Functional expression of the multidrug resistance protein 1 in microglia

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7 January 2021

Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr.

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7 January 2021

Molecular and functional MDR1-Pgp and MRPs expression in human glioblastoma multiforme cell lines

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7 January 2021

Functional expression of P-glycoprotein and multidrug resistance-associated protein (Mrp1) in primary cultures of rat astrocytes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Isolation of endothelial cells from brain, lung, and kidney: expression of the multidrug resistance P-glycoprotein isoforms

1 reference

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7 January 2021

Identification of a major co-receptor for primary isolates of HIV-1

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7 January 2021

Role of activated astrocytes in neuronal damage: potential links to HIV-1-associated dementia

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7 January 2021

HIV-1-induced production of endothelin-1 in an in vitro model of the human blood-brain barrier.

1 reference

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7 January 2021

Efavirenz does not interact with the ABCB1 transporter at the blood-brain barrier

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7 January 2021

Nitric oxide mediates increased P-glycoprotein activity in interferon-{gamma}-stimulated human intestinal cells

1 reference

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7 January 2021

Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug interactions

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7 January 2021

A multidrug resistance transporter from human MCF-7 breast cancer cells

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7 January 2021

Interleukin-6-type cytokines upregulate expression of multidrug resistance-associated proteins in NHEK and dermal fibroblasts.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists

1 reference

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7 January 2021

Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Peptide mimetic HIV protease inhibitors are ligands for the orphan receptor SXR.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood–brain barrier

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1.

1 reference

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7 January 2021

Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

P-glycoprotein expression in rat brain endothelial cells: evidence for regulation by transient oxidative stress.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

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7 January 2021

Evolving paradigms in the pathogenesis of HIV-1-associated dementia

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7 January 2021

https://api.crossref.org/works/10.1002%2FGLIA.20725

1 reference

7 January 2021

Polypharmacy in HIV: impact of data source and gender on reported drug utilization.

1 reference

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7 January 2021

Neural immunity: Friend or foe?

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7 January 2021

Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes

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7 January 2021

Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

1 reference

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7 January 2021

HIV-1 associated dementia: symptoms and causes

1 reference

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7 January 2021

HIV-1 and IL-1 beta regulate Fas ligand expression in human astrocytes through the NF-kappa B pathway

1 reference

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7 January 2021

Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Study of receptor-mediated neurotoxins released by HIV-1-infected mononuclear phagocytes found in human brain

1 reference

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7 January 2021

Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

P-Glycoprotein on astrocyte foot processes of unfixed isolated human brain capillaries.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Genetic analysis of the multidrug transporter

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2).

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Selective interaction of JNK protein kinase isoforms with transcription factors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Transcription factor ATF2 regulation by the JNK signal transduction pathway

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Interactions of HIV protease inhibitors with ATP-dependent drug export proteins

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Rapid modulation of P-glycoprotein-mediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharide.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-TAT protein upregulates expression of multidrug resistance protein 1 in the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-Tat protein induces P-glycoprotein expression in brain microvascular endothelial cells.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

St Johns wort increases expression of P-glycoprotein: implications for drug interactions

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Structure of the multidrug resistance P-glycoprotein

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Expression of mRNAs of multidrug resistance proteins (Mrps) in cultured rat astrocytes, oligodendrocytes, microglial cells and neurones.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

The multidrug resistance protein MRP1 mediates the release of glutathione disulfide from rat astrocytes during oxidative stress

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Expression of multidrug resistance proteins (Mrps) in astrocytes of the mouse brain: a single cell RT-PCR study.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Glutathione release from cultured brain cells: multidrug resistance protein 1 mediates the release of GSH from rat astroglial cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS).

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s)

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

P-glycoprotein limits oral availability, brain, and fetal penetration of saquinavir even with high doses of ritonavir

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Inhibition of P-glycoprotein and multidrug resistance-associated proteins modulates the intracellular concentration of lopinavir in cultured CD4 T cells and primary human lymphocytes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Astrocytes induce blood–brain barrier properties in endothelial cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

P-glycoprotein in blood-brain barrier endothelial cells: interaction and oligomerization with caveolins.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-1 infection and AIDS: consequences for the central nervous system

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Human immunodeficiency virus type 1 (HIV-1) induces activation of multiple STATs in CD4+ cells of lymphocyte or monocyte/macrophage lineages

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Functional CXCR4 receptor development parallels sensitivity to HIV-1 gp120 in cultured rat astroglial cells but not in cultured rat cortical neurons

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

The effects of the HIV-1 envelope protein gp120 on the production of nitric oxide and proinflammatory cytokines in mixed glial cell cultures

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Endothelin-1 stimulates glial cell line-derived neurotrophic factor expression in cultured rat astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Relationship of antiretroviral treatment to postmortem brain tissue viral load in human immunodeficiency virus-infected patients

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Changing patterns in the neuropathogenesis of HIV during the HAART era.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

New proteins configure a brain drug resistance map in tuberous sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Expression of the ATP-binding cassette membrane transporter, ABCG2, in human and rodent brain microvessel endothelial and glial cell culture systems

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Investigation of efflux transport of dehydroepiandrosterone sulfate and mitoxantrone at the mouse blood-brain barrier: a minor role of breast cancer resistance protein

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Mrp4 confers resistance to topotecan and protects the brain from chemotherapy

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Human immunodeficiency virus type 1 enters brain microvascular endothelia by macropinocytosis dependent on lipid rafts and the mitogen-activated protein kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

CD4-independent infection of astrocytes by human immunodeficiency virus type 1: requirement for the human mannose receptor

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

AIDS dementia complex with generalized myoclonus.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Differential CD4/CCR5 utilization, gp120 conformation, and neutralization sensitivity between envelopes from a microglia-adapted human immunodeficiency virus type 1 and its parental isolate

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. The HIV Neurobehavioral Research Center

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Human immunodeficiency virus-associated dementia: an evolving disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Visualization of the intracellular behavior of HIV in living cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV pharmacology: barriers to the eradication of HIV from the CNS.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Paroxysmal dyskinesias in patients with HIV infection.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes. A hit and run phenomenon.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

The AIDS dementia complex: I. Clinical features

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Structural analyses of purified human immunodeficiency virus type 1 intracellular reverse transcription complexes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Human immunodeficiency virus type 1 Tat protein induces death by apoptosis in primary human neuron cultures.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Hepatotoxicity observed in clinical trials of aplaviroc (GW873140)

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Unraveling the neuroimmune mechanisms for the HIV-1-associated cognitive/motor complex

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Lopinavir/ritonavir: a review of its use in the management of HIV infection

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

P-glycoprotein and mutlidrug resistance-associated proteins limit the brain uptake of saquinavir in mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Atazanavir: effects on P-glycoprotein transport and CYP3A metabolism in vitro.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Rapid assessment of P-glycoprotein inhibition and induction in vitro

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Ritonavir induces P-glycoprotein expression, multidrug resistance-associated protein (MRP1) expression, and drug transporter-mediated activity in a human intestinal cell line

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Saint John's wort: an in vitro analysis of P-glycoprotein induction due to extended exposure

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Nelfinavir: a review of its use in the management of HIV infection

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Mononuclear phagocyte immunity and the neuropathogenesis of HIV-1 infection

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Blood-brain barrier: structural components and function under physiologic and pathologic conditions

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

The oligodendrocyte and its many cellular processes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Indinavir concentrations and St John's wort.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

ABCG2: structure, function and role in drug response

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-1 tat protein upregulates inflammatory mediators and induces monocyte invasion into the brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Abundant expression of HIV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Molecular insights on the cerebral innate immune system

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

ABCG2-mediated transport of photosensitizers: potential impact on photodynamic therapy

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-1 viral envelope glycoprotein gp120 triggers an inflammatory response in cultured rat astrocytes and regulates the functional expression of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein-1 (Mrp1) in glial cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Involvement of P-glycoprotein in the transport of saquinavir and indinavir in rat brain microvessel endothelial and microglia cell lines

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-associated cognitive impairment before and after the advent of combination therapy

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Low blood CD8+ T-lymphocytes and high circulating monocytes are predictors of HIV-1-associated progressive encephalopathy in children.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

P-glycoprotein and caveolin-1alpha in endothelium and astrocytes of primate brain.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

P-glycoprotein-mediated active efflux of the anti-HIV1 nucleoside abacavir limits cellular accumulation and brain distribution

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Shedding light on drug transport: structure and function of the P-glycoprotein multidrug transporter (ABCB1).

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Phase I and II study of the safety, virologic effect, and pharmacokinetics/pharmacodynamics of single-dose 3-o-(3',3'-dimethylsuccinyl)betulinic acid (bevirimat) against human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Differential effects of PPARgamma agonists on the metabolic properties of gliomas and astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-infection of the central nervous system: the tightrope walk of innate immunity

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Expression and functional activity of the ABC-transporter proteins P-glycoprotein and multidrug-resistance protein 1 in human brain tumor cells and astrocytes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Human immunodeficiency virus protease inhibitors serve as substrates for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Induction of intercellular adhesion molecule-1 on human brain endothelial cells by HIV-1 gp120: role of CD4 and chemokine coreceptors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Comparison of the inhibitory activity of anti-HIV drugs on P-glycoprotein

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Decreased expression of P-glycoprotein in interleukin-1beta and interleukin-6 treated rat hepatocytes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Atazanavir: a review of its use in the management of HIV infection

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Current status of antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Induction of ABCC3 (MRP3) by pregnane X receptor activators

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HIV-Tat protein induces oxidative and inflammatory pathways in brain endothelium

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Effects of human immunodeficiency virus protease inhibitors on the intestinal absorption of tenofovir disoproxil fumarate in vitro.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Regulation of transcription by MAP kinase cascades

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Detection of HIV‐1 DNA in Microglia/ Macrophages, Astrocytes and Neurons Isolated from Brain Tissue with HIV‐1 Encephalitis by Laser Capture Microdissection

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

CXCR4 mediates entry and productive infection of syncytia-inducing (X4) HIV-1 strains in primary macrophages

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Macrophages and HIV-1: dangerous liaisons

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Fetal blood-brain barrier P-glycoprotein contributes to brain protection during human development

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

N-acetylcysteine prevents HIV gp 120-related damage of human cultured astrocytes: correlation with glutamine synthase dysfunction

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Astrocytes, from brain glue to communication elements: the revolution continues

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Protease inhibitor-based regimens for HIV therapy: safety and efficacy.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Antioxidant protection from HIV-1 gp120-induced neuroglial toxicity

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Controversy surrounding the existence of discrete functional classes of astrocytes in adult gray matter

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Reduced expression of glutamate transporter EAAT2 and impaired glutamate transport in human primary astrocytes exposed to HIV-1 or gp120.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Modulation of human BCRP (ABCG2) activity by anti-HIV drugs

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside reverse transcriptase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Comparison of the induction of P-glycoprotein activity by nucleotide, nucleoside, and non-nucleoside reverse transcriptase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2).

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: implications for the neuropathogenesis of AIDS.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Role for the oligodendrocyte cytoskeleton in myelination

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Clinical implications of CNS penetration of antiretroviral drugs

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

ABCC13, an unusual truncated ABC transporter, is highly expressed in fetal human liver

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

CXCR-4 is expressed by primary macrophages and supports CCR5-independent infection by dual-tropic but not T-tropic isolates of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Intracellular Tat of human immunodeficiency virus type 1 activates lytic cycle replication of Kaposi's sarcoma-associated herpesvirus: role of JAK/STAT signaling.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

The expression and functional characterization of ABCG2 in brain endothelial cells and vessels

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Expression of inducible nitric oxide synthase, interleukin-1 and caspase-1 in HIV-1 encephalitis.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Reversal of P-glycoprotein-mediated multidrug resistance in cancer cells by the c-Jun NH2-terminal kinase

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

HERG-like K+ channels in microglia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20725

7 January 2021

Identifiers

DOI

10.1002/GLIA.20725

1 reference

19 August 2017

1 reference