Rhein protects pancreatic β-cells from dynamin-related protein-1-mediated mitochondrial fission and cell apoptosis under hyperglycemia (Q37251144)

19 August 2017

Rhein protects pancreatic β-cells from dynamin-related protein-1-mediated mitochondrial fission and cell apoptosis under hyperglycemia (English)

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19 August 2017

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mitochondrial fission

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Jing Liu

1

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19 August 2017

Zhaohong Chen

2

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19 August 2017

Yujing Zhang

3

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19 August 2017

Mingchao Zhang

4

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19 August 2017

Xiaodong Zhu

5

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19 August 2017

Yun Fan

6

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19 August 2017

Shaolin Shi

7

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19 August 2017

Ke Zen

8

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19 August 2017

Zhihong Liu

9

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19 August 2017

language of work or name

English

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publication date

6 August 2013

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19 August 2017

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19 August 2017

62

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19 August 2017

11

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19 August 2017

3927-3935

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

19 August 2017

start time

30 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells

9 September 2017

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9 September 2017

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Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus

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Circulating endothelial progenitor cells and cellular membrane microparticles in db/db diabetic mouse: possible implications in cerebral ischemic damage

9 September 2017

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Human mast cell degranulation and preformed TNF secretion require mitochondrial translocation to exocytosis sites: relevance to atopic dermatitis

9 September 2017

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High glucose disrupts mitochondrial morphology in retinal endothelial cells: implications for diabetic retinopathy

9 September 2017

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Prohibitin is expressed in pancreatic beta-cells and protects against oxidative and proapoptotic effects of ethanol.

9 September 2017

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Mitochondrial networking protects beta-cells from nutrient-induced apoptosis.

9 September 2017

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Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus

9 September 2017

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Rhein reverses the diabetic phenotype of mesangial cells over-expressing the glucose transporter (GLUT1) by inhibiting the hexosamine pathway

9 September 2017

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Glucolipotoxicity: fuel excess and beta-cell dysfunction.

9 September 2017

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Role of mitochondrial remodeling in programmed cell death in Drosophila melanogaster

9 September 2017

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Anti-cancer properties of anthraquinones from rhubarb

9 September 2017

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9 September 2017

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9 September 2017

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Alterations of mitochondrial DNA in common diseases and disease states: aging, neurodegeneration, heart failure, diabetes, and cancer

9 September 2017

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Mitochondrial dysfunction and type 2 diabetes

9 September 2017

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Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes

9 September 2017

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Glucotoxicity and beta-cell failure in type 2 diabetes mellitus

9 September 2017

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Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

9 September 2017

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Mitochondrial function in normal and diabetic beta-cells

9 September 2017

1 reference

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The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

9 September 2017

1 reference

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Mitochondria and neuronal survival

9 September 2017

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The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

9 September 2017

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Improvement of glucose tolerance by rhein with restored early-phase insulin secretion in db/db mice

9 September 2017

1 reference

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Rhein ameliorates fatty liver disease through negative energy balance, hepatic lipogenic regulation, and immunomodulation in diet-induced obese mice

14 September 2017

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Rhein induced apoptosis through the endoplasmic reticulum stress, caspase- and mitochondria-dependent pathways in SCC-4 human tongue squamous cancer cells.

14 September 2017

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14 September 2017

1 reference

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Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806614

GPR40 is partially required for insulin secretion following activation of beta3-adrenergic receptors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806614

Insulin-like growth factor-1 receptor activation prevents high glucose-induced mitochondrial dysfunction, cytochrome-c release and apoptosis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806614

Rhein inhibits TNF-alpha-induced human aortic smooth muscle cell proliferation via mitochondrial-dependent apoptosis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806614

A chemical inhibitor of DRP1 uncouples mitochondrial fission and apoptosis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806614

Combined therapy of rhein and benazepril on the treatment of diabetic nephropathy in db/db mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806614

Protective effect of gliclazide on diabetic peripheral neuropathy through Drp-1 mediated-oxidative stress and apoptosis

3 September 2018

1 reference

12 December 2020

Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1

1 reference

12 December 2020

A comparative study on the tissue distributions of rhubarb anthraquinones in normal and CCl4-injured rats orally administered rhubarb extract

1 reference

12 December 2020

Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis

1 reference

12 December 2020

Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB13-0251

1 reference

19 August 2017

1 reference

19 August 2017

1 reference