The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer. (Q37321593)

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25 March 2020

title

The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer (English)

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25 March 2020

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Nuri A Temiz

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Rachel Isaksson Vogel

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Douglas Yee

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Reuben S Harris

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Marion E Meijer-van Gelder

25 March 2020

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Marion E Meijer-van Gelder

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John A Foekens

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25 March 2020

author name string

Emily K Law

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Kelly LaPara

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Brandon Leonard

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language of work or name

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7 October 2016

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volume

2

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25 March 2020

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e1601737

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describes a project that uses

25 March 2020

ImageQuant

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11 June 2022

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APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation

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A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3'UTR enhances chromosomal DNA damage

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Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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APOBEC3A can activate the DNA damage response and cause cell-cycle arrest

6 September 2017

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6 September 2017

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APOBEC3 proteins mediate the clearance of foreign DNA from human cells

6 September 2017

1 reference

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The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival.

6 September 2017

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Progesterone receptor-B regulation of insulin-like growth factor-stimulated cell migration in breast cancer cells via insulin receptor substrate-2.

6 September 2017

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Population stratification of a common APOBEC gene deletion polymorphism

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

1 reference

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Evaluation of the ability of adjuvant tamoxifen-benefit gene signatures to predict outcome of hormone-naive estrogen receptor-positive breast cancer patients treated with tamoxifen in the advanced setting.

6 September 2017

1 reference

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APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development

28 September 2017

1 reference

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Annual hazard rates of recurrence for breast cancer after primary therapy.

26 June 2018

1 reference

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Human APOBEC3B is a potent inhibitor of HIV-1 infectivity and is resistant to HIV-1 Vif.

26 June 2018

1 reference

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Parsing Progress in Breast Cancer

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27730215

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIADV.1601737

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27730215%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27730215%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

PubMed publication ID

27730215

1 reference