TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells (Q37330560)

19 August 2017

TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells (English)

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19 August 2017

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3

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2 June 2020

author name string

Hisa Hui Ling Tseng

1

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2 June 2020

Chi Teng Vong

2

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2 June 2020

Simon Ming-Yuen Lee

4

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2 June 2020

Maggie Pui Man Hoi

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English

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publication date

12 October 2016

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19 August 2017

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2 June 2020

volume

6

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2 June 2020

page(s)

35016

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Creative Commons Attribution 4.0 International

2 June 2020

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start time

12 October 2016

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ImageJ

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11 June 2022

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https://scigraph.springernature.com/pub.10.1038/srep35016

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Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1beta transcription in human adipose tissue

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High glucose-induced oxidative stress increases transient receptor potential channel expression in human monocytes

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Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein

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TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

6 September 2017

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Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation

6 September 2017

1 reference

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Transcriptional regulation of cytokines and oxidative stress by gallic acid in human THP-1 monocytes

14 September 2017

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Inhibition of TRPM2 cation channels by N-(p-amylcinnamoyl)anthranilic acid.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059733

High Glucose-Induced Expression of Proinflammatory Cytokine and Chemokine Genes in Monocytic Cells

14 September 2017

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Structure and function of poly(ADP-ribose) polymerase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059733

High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059733

Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells

1 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059733

Ca(2+)-dependent p47phox translocation in hydroperoxide modulation of the alveolar macrophage respiratory burst.

1 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059733

TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1.

1 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059733

Ursolic acid attenuates D-galactose-induced inflammatory response in mouse prefrontal cortex through inhibiting AGEs/RAGE/NF-κB pathway activation.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059733

Lack of TXNIP protects beta-cells against glucotoxicity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059733

High glucose enhances transient receptor potential channel canonical type 6-dependent calcium influx in human platelets via phosphatidylinositol 3-kinase-dependent pathway

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059733

Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059733

Proteasome activation by poly-ADP-ribose-polymerase in human myelomonocytic cells after oxidative stress.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5059733

Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27731349

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12 December 2020

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Lack of Interleukin-1β Decreases the Severity of Atherosclerosis in ApoE-Deficient Mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27731349

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12 December 2020

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Identifiers

DOI

10.1038/SREP35016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27731349%20AND%20SRC:MED&resulttype=core&format=json

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2 June 2020

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2 June 2020

PubMed publication ID

27731349

1 reference