Exploring the immunology of parasitism--from surface antigens to the hygiene hypothesis (Q37491369)

20 August 2017

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title

Exploring the immunology of parasitism--from surface antigens to the hygiene hypothesis (English)

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20 August 2017

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R M Maizels

1

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20 August 2017

22 May 2009

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20 August 2017

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20 August 2017

136

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20 August 2017

12

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20 August 2017

1549-1564

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Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis

20 August 2017

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Characterization of nematode glycoproteins: the major O-glycans of Toxocara excretory-secretory antigens are O-methylated trisaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

A new class of anthelmintics effective against drug-resistant nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Helminth infections: the great neglected tropical diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Resistance and susceptibility in human onchocerciasis--beyond Th1 vs. Th2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

The secretome of the filarial parasite, Brugia malayi: proteomic profile of adult excretory-secretory products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Cloning and characterization of Ancylostoma-secreted protein. A novel protein associated with the transition to parasitism by infective hookworm larvae

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Modulation of host immune responses by nematode cystatins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Homologues of human macrophage migration inhibitory factor from a parasitic nematode. Gene cloning, protein activity, and crystal structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Subversion of immune cell signal transduction pathways by the secreted filarial nematode product, ES-62.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Serine proteinase inhibitors from nematodes and the arms race between host and pathogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Comprehensive analysis of the secreted proteins of the parasite Haemonchus contortus reveals extensive sequence variation and differential immune recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

The Secreted Larval Acidic Proteins (SLAPs) of Onchocerca spp. are encoded by orthologues of the alt gene family of Brugia malayi and have host protective potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Suppression of allergic airway inflammation by helminth-induced regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Regulation of allergy and autoimmunity in helminth infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Ancylostoma caninum MTP-1, an astacin-like metalloprotease secreted by infective hookworm larvae, is involved in tissue migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Phosphorylcholine mimics the effects of ES-62 on macrophages and dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

The ICT Filariasis Test: A rapid-format antigen test for diagnosis of bancroftian filariasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

A novel member of the transforming growth factor-beta (TGF-beta) superfamily from the filarial nematodes Brugia malayi and B. pahangi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Orthologs of macrophage migration inhibitory factor from parasitic nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Identification of tgh-2, a filarial nematode homolog of Caenorhabditis elegans daf-7 and human transforming growth factor beta, expressed in microfilarial and adult stages of Brugia malayi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Draft genome of the filarial nematode parasite Brugia malayi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

An abundantly expressed mucin-like protein from Toxocara canis infective larvae: the precursor of the larval surface coat glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Inhibition of Fc epsilon RI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

An abundant, trans-spliced mRNA from Toxocara canis infective larvae encodes a 26-kDa protein with homology to phosphatidylethanolamine-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Biochemical properties of larval excretory-secretory glycoproteins of the parasitic nematode Toxocara canis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Expansion of Foxp3+ regulatory T cells in mice infected with the filarial parasite Brugia malayi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Expansion and activation of CD4(+)CD25(+) regulatory T cells in Heligmosomoides polygyrus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

A microbial symbiosis factor prevents intestinal inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Immune regulation by helminth parasites: cellular and molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Toxocara canis: genes expressed by the arrested infective larval stage of a parasitic nematode

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Molecules on the Surface of Parasitic Nematodes as Probes of the Immune Response in Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Brugia pahangi and Brugia malayi: a surface-associated glycoprotein (gp15/400) is composed of multiple tandemly repeated units and processed from a 400-kDa precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Early recruitment of natural CD4+ Foxp3+ Treg cells by infective larvae determines the outcome of filarial infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

The serpin secreted by Brugia malayi microfilariae, Bm-SPN-2, elicits strong, but short-lived, immune responses in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Immunization of mice with surface antigens from the muscle larvae of Trichinella spiralis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Cystatins from filarial parasites: evolution, adaptation and function in the host-parasite relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Differentially expressed, abundant trans-spliced cDNAs from larval Brugia malayi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

The abundant larval transcript-1 and -2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Alternative activation of macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Allergy, parasites, and the hygiene hypothesis

21 January 2018

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https://api.crossref.org/works/10.1017%2FS0031182009006106

Dynamics of lung macrophage activation in response to helminth infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Full-length-enriched cDNA libraries from Echinococcus granulosus contain separate populations of oligo-capped and trans-spliced transcripts and a high level of predicted signal peptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Toxocara canis: interaction of human blood eosinophils with the infective larvae

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

A Brugia malayi homolog of macrophage migration inhibitory factor reveals an important link between macrophages and eosinophil recruitment during nematode infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

O-methylated glycans from Toxocara are specific targets for antibody binding in human and animal infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Cytokine-mediated regulation of chronic intestinal helminth infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Helminths as governors of immune-mediated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL-10 and transforming growth factor-beta but not by a T(h)1 to T(h)2 shift

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Immunological tolerance: The key feature in human filariasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

The biochemical and immunochemical characterisation of the 30 kilodalton surface antigen of Brugia pahangi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Filarial surface antigens: the major 29 kilodalton glycoprotein and a novel 17-200 kilodalton complex from adult Brugia malayi parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Expression of helminth genes in Leishmania: an experimental transfection system to test immunological function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Immune evasion genes from filarial nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

T regulatory-1 cells induce IgG4 production by B cells: role of IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Depression of antigen-specific interleukin-5 and interferon-gamma responses in human lymphatic filariasis as a function of clinical status and age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

In Th2-biased lymphatic filarial patients, responses to purified protein derivative of Mycobacterium tuberculosis remain Th1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Regulatory T cells: key controllers of immunologic self-tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

MIF homologues from a filarial nematode parasite synergize with IL-4 to induce alternative activation of host macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Age-specific acquisition of immunity to infective larvae in a bancroftian filariasis endemic area of Papua New Guinea

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Serum IgG and IgG4 antibodies to Fel d 1 among children exposed to 20 microg Fel d 1 at home: relevance of a nonallergic modified Th2 response

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Association between parasite infection and immune responses in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Immune response to stage-specific surface antigens of the parasitic nematode Trichinella spiralis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Identification of the major soluble cuticular glycoprotein of lymphatic filarial nematode parasites (gp29) as a secretory homolog of glutathione peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Changing proteins on the surface of a parasitic nematode

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Cutting edge: dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminth-specific Th2 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Four abundant novel transcript genes from Toxocara canis with unrelated coding sequences share untranslated region tracts implicated in the control of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

A new C-type lectin similar to the human immunoreceptor DC-SIGN mediates symbiont acquisition by a marine nematode.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

cDNA clones of Onchocerca volvulus low molecular weight antigens provide immunologically specific diagnostic probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Phosphorylcholine-bearing antigens in filarial nematode parasites: analysis of somatic extracts, in-vitro secretions and infection sera from Brugia malayi and B. pahangi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Cis and trans mRNA splicing in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Immunological genomics of Brugia malayi: filarial genes implicated in immune evasion and protective immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Genes expressed in Brugia malayi infective third stage larvae

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Infections and allergy - helminths, hygiene and host immune regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Nematode surface coats: actively evading immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Alarming dendritic cells for Th2 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

A novel C-type lectin secreted by a tissue-dwelling parasitic nematode

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Helminth C-type lectins and host-parasite interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

A family of secreted mucins from the parasitic nematode Toxocara canis bears diverse mucin domains but shares similar flanking six-cysteine repeat motifs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Toxocara canis: A labile antigenic surface coat overlying the epicuticle of infective larvae

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Toxocara canis: monoclonal antibodies to carbohydrate epitopes of secreted (TES) antigens localize to different secretion-related structures in infective larvae

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Immunological aspects of lymphatic filariasis and onchocerciasis in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Bm-CPI-2, a cystatin from Brugia malayi nematode parasites, differs from Caenorhabditis elegans cystatins in a specific site mediating inhibition of the antigen-processing enzyme AEP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Characterisation of the secretory acetylcholinesterases from adult Nippostrongylus brasiliensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Expression and immune recognition of Brugia malayi VAL-1, a homologue of vespid venom allergens and Ancylostoma secreted proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Immune-mediated adherence of eosinophils to Toxocara canis infective larvae: the role of excretory-secretory antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Identification of a new C-type lectin, TES-70, secreted by infective larvae of Toxocara canis, which binds to host ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Synthesis of neoglycoproteins containing O-methylated trisaccharides related to excretory/secretory antigens of Toxocara larvae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Th1-Th2: reliable paradigm or dangerous dogma?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Juvenile female Litomosoides sigmodontis produce an excretory/secretory antigen (Juv-p120) highly modified with dimethylaminoethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Decreased atopy in children infected with Schistosoma haematobium: a role for parasite-induced interleukin-10

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

APC from mice harbouring the filarial nematode, Brugia malayi, prevent cellular proliferation but not cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

A transcriptomic analysis of the phylum Nematoda

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Parasite immunity: Pathways for expelling intestinal helminths

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Selective maturation of dendritic cells byNippostrongylus brasiliensis-secreted proteins drives Th2 immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

Filarial nematode parasites secrete a homologue of the human cytokine macrophage migration inhibitory factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Onchocerca volvulus: detection of circulating antigen by monoclonal antibodies in human onchocerciasis.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Purification and properties of monomeric (G1) forms of acetylcholinesterase secreted by Nippostrongylus brasiliensis

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Variation and polymorphism in helminth parasites.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Analysis of Toxocara canis larval excretory-secretory antigens: physicochemical characterization and antibody recognition.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Structural organisation and lipid composition of the epicuticular accessory layer of infective larvae of Trichinella spiralis

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Characterization of proteolytic enzymes from larval and adultNippostrongylus brasiliensis

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Secreted antigens of filarial nematodes: a survey and characterization of in vitro excreted/secreted products of adult Brugia malayi

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Epitope specificity of the T cell proliferative response to lysozyme: proliferative T cells react predominantly to different determinants from those recognized by B cells

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Secreted and circulating antigens of the filarial parasite Brugia pahangi: analysis of in vitro released components and detection of parasite products in vivo

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Characterization of surface and excretory-secretory antigens of Toxocara canis infective larvae

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Cross-reactive surface antigens on three stages of Brugia malayi, B. pahangi and B. timori

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Microsatellite analysis reveals marked genetic differentiation between Haemonchus contortus laboratory isolates and provides a rapid system of genetic fingerprinting

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Elevated cellular immune responses and interferon-gamma release after long-term diethylcarbamazine treatment of patients with human lymphatic filariasis

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Identification, synthesis and immunogenicity of cuticular collagens from the filarial nematodes Brugia malayi and Brugia pahangi

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

CTLA-4 and CD4+ CD25+ regulatory T cells inhibit protective immunity to filarial parasites in vivo

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Secreted and surface antigens from larval stages of Wuchereria bancrofti, the major human lymphatic filarial parasite

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Brugia pahangi: labelling of secreted antigens with 35S-methionine in vitro

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

Antigenic characterization of adult Wuchereria bancrofti filarial nematodes

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009006106

7 January 2021

10.1017/S0031182009006106

Identifiers

DOI

1 reference

20 August 2017

1 reference

PubMed ID

19460185