Cellular stress response pathway system as a sentinel ensemble in toxicological screening (Q37536673)

20 August 2017

1 reference

title

Cellular stress response pathway system as a sentinel ensemble in toxicological screening (English)

1 reference

20 August 2017

Steven O Simmons

1

1 reference

PubMed ID

19567883

20 August 2017

Chun-Yang Fan

series ordinal

2

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PubMed ID

19567883

20 August 2017

Ram Ramabhadran

series ordinal

3

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20 August 2017

30 June 2009

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20 August 2017

Toxicological Sciences

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20 August 2017

111

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20 August 2017

2

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20 August 2017

202-225

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Determination of interleukin-4-responsive region in the human cytochrome P450 2E1 gene promoter

20 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Activation of the hsp70 promoter by environmental inorganic and organic chemicals: relationships with cytotoxicity and lipophilicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Dissecting hematopoiesis and disease using the zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The activity of hsp90 alpha promoter is regulated by NF-kappa B transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Metal-dependent binding of a factor in vivo to the metal-responsive elements of the metallothionein 1 gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Regulation of metallothionein gene expression by oxidative stress and metal ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Cigarette smoke condensate activates nuclear transcription factor-kappaB through phosphorylation and degradation of IkappaB(alpha): correlation with induction of cyclooxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

An essential role for p300/CBP in the cellular response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Activating transcription factor 4 overexpression inhibits proliferation and differentiation of mammary epithelium resulting in impaired lactation and accelerated involution

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Human cell lines in pharmacotoxicology. An introduction to a panel discussion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The aryl hydrocarbon receptor complex and the control of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Developmental toxicology of cadmium in living embryos of a stable transgenic zebrafish line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

p53 in embryonic development: maintaining a fine balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

A murine world without HSFs: meeting report

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The stress or heat shock (HS) response: insights from transgenic mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Manganese induces endoplasmic reticulum (ER) stress and activates multiple caspases in nigral dopaminergic neuronal cells, SN4741.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Oxidative stress activates metal-responsive transcription factor-1 binding activity. Occupancy in vivo of metal response elements in the metallothionein-I gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Tumour necrosis factor-alpha stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-kappaB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Definition of a consensus binding site for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

p53 suppresses the Nrf2-dependent transcription of antioxidant response genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

cAMP-independent role of PKA in tonicity-induced transactivation of tonicity-responsive enhancer/ osmotic response element-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Oxidants, oxidative stress and the biology of ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Recombinant cell lines for stress reporter assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Activation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

MEKK1/JNK signaling stabilizes and activates p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

p38 signaling-mediated hypoxia-inducible factor 1 alpha and vascular endothelial growth factor induction by Cr(VI) in DU145 human prostate carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Lost in transcription: p21 repression, mechanisms, and consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

NF-kappaB activation by reactive oxygen species: fifteen years later

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

EBV latent membrane protein-1 protects B cells from apoptosis by inhibition of BAX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Transcription factor-kappa B (NF-kappa B) and renal disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

NF-kappaB activation by double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Endoplasmic reticulum stress and the development of diabetes: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

High-specificity and high-sensitivity genotoxicity assessment in a human cell line: validation of the GreenScreen HC GADD45a-GFP genotoxicity assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Shared principles in NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

ATM-dependent and -independent gene expression changes in response to oxidative stress, gamma irradiation, and UV irradiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Cellular stress response and apoptosis in cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Zebrafish as a model vertebrate for investigating chemical toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Real-time detection and continuous monitoring of ER stress in vitro and in vivo by ES-TRAP: evidence for systemic, transient ER stress during endotoxemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The NPM-ALK oncoprotein abrogates CD30 signaling and constitutive NF-kappaB activation in anaplastic large cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Coping with stress: multiple ways to activate p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Understanding mechanisms of toxicity: insights from drug discovery research

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Characterization of diversity in toxicity mechanism using in vitro cytotoxicity assays in quantitative high throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Use of transgenic luciferase reporter mice to determine activation of transcription factors and gene expression by fibrogenic particles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

ATM, a DNA damage-inducible kinase, contributes to activation by high NaCl of the transcription factor TonEBP/OREBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Activator protein-1 contributes to high NaCl-induced increase in tonicity-responsive enhancer/osmotic response element-binding protein transactivating activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Proteasomal inhibition attenuates transcriptional activity of hypoxia-inducible factor 1 (HIF-1) via specific effect on the HIF-1alpha C-terminal activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Molecular mechanism of nrf2 activation by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The VHL tumor suppressor and HIF: insights from genetic studies in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Induction of cellular antioxidative stress genes through heterodimeric transcription factor Nrf2/small Maf by antirheumatic gold(I) compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

PKC downstream of Pl3-kinase regulates peroxynitrite formation for Nrf2-mediated GSTA2 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicity-responsive enhancer-binding protein (OREBP/TonEBP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Cadmium-responsive element of the human heme oxygenase-1 gene mediates heat shock factor 1-dependent transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Molecular and evolutionary basis of the cellular stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

What sets the TonE during osmotic stress?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Dynamics of the p53-Mdm2 feedback loop in individual cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Understanding the mechanisms of zinc-sensing by metal-response element binding transcription factor-1 (MTF-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Apoptosis, cancer and the p53 tumour suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Hypoxia, drug therapy and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

NF-kappaB regulation in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

p53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Function of polo-like kinase 3 in NF-kappaB-mediated proapoptotic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Animal models of human disease: zebrafish swim into view

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Interaction of a common cellular transcription factor, ATF, with regulatory elements in both E1a- and cyclic AMP-inducible promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Herp is dually regulated by both the endoplasmic reticulum stress-specific branch of the unfolded protein response and a branch that is shared with other cellular stress pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

In vivo bioluminescent monitoring of chemical toxicity using heme oxygenase-luciferase transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Nontoxic proteasome inhibition activates a protective antioxidant defense response in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The nuclear receptor superfamily and drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Mechanisms of cytochrome P450 regulation by inflammatory mediators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Nrf2-Keap1 defines a physiologically important stress response mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The metal-responsive transcription factor-1 contributes to HIF-1 activation during hypoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Identification of a nuclear protein that constitutively recognizes the sequence containing a heat-shock element. Its binding properties and possible function modulating heat-shock induction of the rat heme oxygenase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

P53 mediated regulation of metallothionein transcription in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Adapting the medaka embryo assay to a high-throughput approach for developmental toxicity testing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

p53: at the crossroad between cancer and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Dissection of the NF-kappaB signalling cascade in transgenic and knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Integrating cell-signalling pathways with NF-kappaB and IKK function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Copper activates the NF-kappaB pathway in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Regulation of the DNA binding of p53 by its interaction with protein kinase CK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Inorganic lead activates NF-kappa B in primary human CD4+ T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Activation of early signaling transcription factor, NF-kappaB following low-level manganese exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Ethanol- and acetaldehyde-mediated developmental toxicity in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Transcriptional control of human p53-regulated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

In situ pulmonary localization of air pollution particle-induced oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Gene regulation under low oxygen: holding your breath for transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Zinc induced apoptosis in HEP-2 cancer cells: the role of oxidative stress and mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Tyrosine phosphatases as targets in metal-induced signaling in human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Negative regulation of the heat shock transcriptional response by HSBP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Regulation of metallothionein transcription by the metal-responsive transcription factor MTF-1: identification of signal transduction cascades that control metal-inducible transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Heat and heavy metal stress synergize to mediate transcriptional hyperactivation by metal-responsive transcription factor MTF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Oxidative stress interference with the nuclear factor-kappa B activation pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Endoplasmic reticulum stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

HIF-1-dependent respiratory, cardiovascular, and redox responses to chronic intermittent hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Quantitative GFP fluorescence as an indicator of arsenite developmental toxicity in mosaic heat shock protein 70 transgenic zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Specific activation of the human HSP70 promoter by copper sulfate in mosaic transgenic zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Effects of phenylarsine oxide on expression of heme oxygenase-1 reporter constructs in transiently transfected cultures of chick embryo liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Gadd45alpha does not modulate the carboplatin or 5-fluorouracil-induced apoptosis in human papillomavirus-positive cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Roles of MAPK and NF-kappaB in interleukin-6 induction by lipopolysaccharide in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Critical DNA damage recognition functions of XPC-hHR23B and XPA-RPA in nucleotide excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The CAT-Tox (L) assay: a sensitive and specific measure of stress-induced transcription in transformed human liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Cross talk of heat shock and heavy metal regulatory pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Translational control of gene expression during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Chaperone regulation of the heat shock protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Metal-responsive transcription factor-1 (MTF-1) is essential for embryonic liver development and heavy metal detoxification in the adult liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Biophotonic imaging in HO-1.luc transgenic mice: real-time demonstration of gender-specific chloroform induced renal toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Heat shock response modulators as therapeutic tools for diseases of protein conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Transparent adult zebrafish as a tool for in vivo transplantation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Differential heat shock gene hsp70-1 response to toxicants revealed by in vivo study of lungs in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

TonEBP/NFAT5 stimulates transcription of HSP70 in response to hypertonicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The aryl hydrocarbon nuclear translocator alters CD30-mediated NF-kappaB-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The functional interactions between the p53 and MAPK signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Role of Ras in metal-induced EGF receptor signaling and NF-kappaB activation in human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Development of a heat shock inducible gfp transgenic zebrafish line by using the zebrafish hsp27 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Involvement of NF-kappa B in the induction of NAD(P)H:quinone oxidoreductase (DT-diaphorase) by hypoxia, oltipraz and mitomycin C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Diosgenin induces hypoxia-inducible factor-1 activation and angiogenesis through estrogen receptor-related phosphatidylinositol 3-kinase/Akt and p38 mitogen-activated protein kinase pathways in osteoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The transcriptional targets of p53 in apoptosis control

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Hypoxia-activated metabolic pathway stimulates phosphorylation of p300 and CBP in oxygen-sensitive cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Gadd45a, a p53- and BRCA1-regulated stress protein, in cellular response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

From endoplasmic-reticulum stress to the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

Ataxia telangiectasia-mutated, a DNA damage-inducible kinase, contributes to high NaCl-induced nuclear localization of transcription factor TonEBP/OREBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: opposite roles of p38alpha and p38delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

A transgenic mouse model for the detection of cellular stress induced by toxic inorganic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP140

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFP140

1 reference

20 August 2017

1 reference

PubMed ID

19567883