Recent advance in brown adipose physiology and its therapeutic potential (Q37621009)

21 August 2017

1 reference

11 October 2019

Recent advance in brown adipose physiology and its therapeutic potential (English)

1 reference

21 August 2017

1 reference

11 October 2019

0 references

Yun-Hee Lee

1

1 reference

PMCID

3944445

21 August 2017

Young-Suk Jung

series ordinal

2

1 reference

PMCID

3944445

21 August 2017

Dalwoong Choi

series ordinal

3

1 reference

21 August 2017

21 February 2014

2 references

Experimental and Molecular Medicine

21 August 2017

11 October 2019

2 references

21 August 2017

11 October 2019

46

1 reference

21 August 2017

e78

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

21 August 2017

1 reference

https://scigraph.springernature.com/pub.10.1038/emm.2013.163

11 October 2019

exact match

0 references

cites work

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Anatomical locations of human brown adipose tissue: functional relevance and implications in obesity and type 2 diabetes

23 August 2017

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23 August 2017

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Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat.

23 August 2017

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Beyond the sympathetic tone: the new brown fat activators

23 August 2017

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EBF2 determines and maintains brown adipocyte identity

23 August 2017

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Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs

23 August 2017

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MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16

23 August 2017

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Divergent phenotype of rat thoracic and abdominal perivascular adipose tissues

23 August 2017

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Adaptive thermogenesis in adipocytes: is beige the new brown?

23 August 2017

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BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis

23 August 2017

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15O PET measurement of blood flow and oxygen consumption in cold-activated human brown fat.

23 August 2017

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PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors.

23 August 2017

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Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ

23 August 2017

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Loss of perivascular adipose tissue on peroxisome proliferator-activated receptor-γ deletion in smooth muscle cells impairs intravascular thermoregulation and enhances atherosclerosis

23 August 2017

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Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human

23 August 2017

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Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply

23 August 2017

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BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions

23 August 2017

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Controlling a master switch of adipocyte development and insulin sensitivity: covalent modifications of PPARγ

23 August 2017

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In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding

23 August 2017

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Adipose tissue stem cells: the great WAT hope

23 August 2017

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Reversal of type 1 diabetes in mice by brown adipose tissue transplant.

23 August 2017

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Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes

23 August 2017

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FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

23 August 2017

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NT-PGC-1α protein is sufficient to link β3-adrenergic receptor activation to transcriptional and physiological components of adaptive thermogenesis

23 August 2017

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Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans.

23 August 2017

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Programming human pluripotent stem cells into white and brown adipocytes.

23 August 2017

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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

23 August 2017

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Adipose tissue stem cells meet preadipocyte commitment: going back to the future

23 August 2017

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PDGFRβ signaling regulates mural cell plasticity and inhibits fat development.

23 August 2017

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Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype

23 August 2017

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Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat.

23 August 2017

1 reference

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Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Cellular bioenergetics as a target for obesity therapy

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Brown adipose tissue--a new role in humans?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Distribution and development of brown adipocytes in the murine and human adipose organ

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic [...]

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Fighting fat with fat: the expanding field of adipose stem cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Transdifferentiation properties of adipocytes in the adipose organ

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Functional brown adipose tissue in healthy adults

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Cold-activated brown adipose tissue in healthy men

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

PRDM16 controls a brown fat/skeletal muscle switch

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Control of lipolysis by natriuretic peptides and cyclic GMP.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Developmental origin of fat: tracking obesity to its source.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Transcriptional control of brown fat determination by PRDM16

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Brown adipose tissue: function and physiological significance

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

White adipose tissue contributes to UCP1-independent thermogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

beta(3)-Adrenoceptor agonists: potential, pitfalls and progress

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Adipose tissue metabolism in 2012: Adipose tissue plasticity and new therapeutic targets

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

MyomiR-133 regulates brown fat differentiation through Prdm16.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Inflammation and lipid signaling in the etiology of insulin resistance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Adipogenesis: from stem cell to adipocyte

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Epigenetic codes of PPARγ in metabolic disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Using brown adipose tissue to treat obesity - the central issue.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

TLE3 is a dual-function transcriptional coregulator of adipogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Brown adipose tissue responds to cold and adrenergic stimulation by induction of FGF21.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Trends in quality-adjusted life-years lost contributed by smoking and obesity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Effect of diet and cold exposure on norepinephrine turnover in brown adipose tissue of the rat.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Genome-wide profiling of peroxisome proliferator-activated receptor γ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective binding correlated with gene expression

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Evidence for two types of brown adipose tissue in humans.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Brown adipose tissue activity controls triglyceride clearance.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Noradrenergic parenchymal nerve fiber branching after cold acclimatisation correlates with brown adipocyte density in mouse adipose organ

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Regional-dependent increase of sympathetic innervation in rat white adipose tissue during prolonged fasting.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Decreased brown fat markedly enhances susceptibility to diet-induced obesity, diabetes, and hyperlipidemia.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944445

Adipose tissue as an endocrine organ

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMM.2013.163

Metabolic and cellular plasticity in white adipose tissue I: effects of beta3-adrenergic receptor activation

21 January 2018

1 reference

12 December 2020

Different autonomous myogenic cell populations revealed by ablation of Myf5-expressing cells during mouse embryogenesis

1 reference

12 December 2020

The occurrence of brown adipose tissue in outdoor workers

1 reference

12 December 2020

Hypertrophy of brown adipocytes in brown and white adipose tissues and reversal of diet-induced obesity in rats treated with a beta3-adrenoceptor agonist

1 reference

12 December 2020

Outdoor temperature, age, sex, body mass index, and diabetic status determine the prevalence, mass, and glucose-uptake activity of 18F-FDG-detected BAT in humans

1 reference

12 December 2020

Triiodothyronine induces UCP-1 expression and mitochondrial biogenesis in human adipocytes

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12 December 2020

Identifiers

DOI

10.1038/EMM.2013.163

1 reference

21 August 2017

1 reference

21 August 2017

1 reference

PMCID

3944445