A spectrum of gene regulatory phenomena at mammalian beta-globin gene loci (Q37629622)

21 August 2017

1 reference

title

A spectrum of gene regulatory phenomena at mammalian beta-globin gene loci (English)

1 reference

21 August 2017

George Fromm

1

1 reference

PubMed ID

19898527

21 August 2017

Michael Bulger

series ordinal

2

1 reference

21 August 2017

1 October 2009

1 reference

Biochemistry and Cell Biology

21 August 2017

1 reference

21 August 2017

87

1 reference

21 August 2017

5

1 reference

21 August 2017

781-790

1 reference

21 August 2017

1 reference

Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region.

21 January 2018

1 reference

Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription

21 January 2018

1 reference

CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation

21 January 2018

1 reference

Developmental stage-specific epigenetic control of human beta-globin gene expression is potentiated in hematopoietic progenitor cells prior to their transcriptional activation

21 January 2018

1 reference

Lineage-specific activators affect beta-globin locus chromatin in multipotent hematopoietic progenitors

21 January 2018

1 reference

Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes

21 January 2018

1 reference

A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus

21 January 2018

1 reference

Hypersensitive site 2 specifies a unique function within the human beta-globin locus control region to stimulate globin gene transcription

21 January 2018

1 reference

Coregulation of GATA factors by the Friend of GATA (FOG) family of multitype zinc finger proteins

21 January 2018

1 reference

BCL11A represses HBG transcription in K562 cells

21 January 2018

1 reference

The role of transcriptional activator GATA-1 at human beta-globin HS2

21 January 2018

1 reference

Spatial organization of gene expression: the active chromatin hub.

21 January 2018

1 reference

Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus.

21 January 2018

1 reference

The active spatial organization of the beta-globin locus requires the transcription factor EKLF

21 January 2018

1 reference

Sox6 cell-autonomously stimulates erythroid cell survival, proliferation, and terminal maturation and is thereby an important enhancer of definitive erythropoiesis during mouse development

21 January 2018

1 reference

Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5'HS3 deletion mutations: implication for LCR chromatin architecture

21 January 2018

1 reference

Controlling the double helix

21 January 2018

1 reference

Combinatorial effects of four histone modifications in transcription and differentiation

21 January 2018

1 reference

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

21 January 2018

1 reference

Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death

21 January 2018

1 reference

A global role for EKLF in definitive and primitive erythropoiesis

21 January 2018

1 reference

CpG hypomethylation in a large domain encompassing the embryonic beta-like globin genes in primitive erythrocytes

21 January 2018

1 reference

Deletion of the core region of 5' HS2 of the mouse beta-globin locus control region reveals a distinct effect in comparison with human beta-globin transgenes

21 January 2018

1 reference

Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain

21 January 2018

1 reference

Functional selectivity of recombinant mammalian SWI/SNF subunits

21 January 2018

1 reference

A common precursor for primitive erythropoiesis and definitive haematopoiesis

21 January 2018

1 reference

Distinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequences

21 January 2018

1 reference

Nucleosome and transcription activator antagonism at human beta-globin locus control region DNase I hypersensitive sites

21 January 2018

1 reference

Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation.

21 January 2018

1 reference

"Maturational" globin switching in primary primitive erythroid cells

21 January 2018

1 reference

Reconstitution of human beta-globin locus control region hypersensitive sites in the absence of chromatin assembly.

21 January 2018

1 reference

DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

21 January 2018

1 reference

Individual LCR hypersensitive sites cooperate to generate an open chromatin domain spanning the human beta-globin locus

21 January 2018

1 reference

Activation of Eklf expression during hematopoiesis by Gata2 and Smad5 prior to erythroid commitment

21 January 2018

1 reference

Developmental- and differentiation-specific patterns of human gamma- and beta-globin promoter DNA methylation

21 January 2018

1 reference

Activation of the beta globin locus by transcription factors and chromatin modifiers

21 January 2018

1 reference

A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.

21 January 2018

1 reference

A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins

21 January 2018

1 reference

The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis

21 January 2018

1 reference

Mutation of a transcriptional motif of a distant regulatory element reduces the expression of embryonic and fetal globin genes

21 January 2018

1 reference

The histone acetyltransferase PCAF associates with actin and hnRNP U for RNA polymerase II transcription

21 January 2018

1 reference

Active genes dynamically colocalize to shared sites of ongoing transcription

21 January 2018

1 reference

Regulation of erythroid Krüppel-like factor (EKLF) transcriptional activity by phosphorylation of a protein kinase casein kinase II site within its interaction domain.

21 January 2018

1 reference

Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders

21 January 2018

1 reference

Autonomous developmental control of human embryonic globin gene switching in transgenic mice.

21 January 2018

1 reference

Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.

21 January 2018

1 reference

Activation of beta-major globin gene transcription is associated with recruitment of NF-E2 to the beta-globin LCR and gene promoter

21 January 2018

1 reference

The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation

21 January 2018

1 reference

Acetylation of EKLF is essential for epigenetic modification and transcriptional activation of the beta-globin locus

21 January 2018

1 reference

Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression

21 January 2018

1 reference

Control of globin gene expression during development and erythroid differentiation

21 January 2018

1 reference

Looping and interaction between hypersensitive sites in the active beta-globin locus

21 January 2018

1 reference

Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1.

21 January 2018

1 reference

Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin

21 January 2018

1 reference

Phenotype-genotype relationships in monogenic disease: lessons from the thalassaemias.

21 January 2018

1 reference

Chromosomal subunits in active genes have an altered conformation

21 January 2018

1 reference

Sox6 directly silences epsilon globin expression in definitive erythropoiesis

21 January 2018

1 reference

Histone acetylation at the human beta-globin locus changes with developmental age.

21 January 2018

1 reference

Heme induces ubiquitination and degradation of the transcription factor Bach1

21 January 2018

1 reference

Site-specific acetylation by p300 or CREB binding protein regulates erythroid Krüppel-like factor transcriptional activity via its interaction with the SWI-SNF complex

21 January 2018

1 reference

Human γ-globin genes silenced independently of other genes in the β-globin locus

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1139/O09-048

1 reference

21 August 2017

1 reference

PubMed ID

19898527