Chaperone-assisted degradation: multiple paths to destruction (Q37714916)

22 August 2017

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title

Chaperone-assisted degradation: multiple paths to destruction (English)

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22 August 2017

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Nadja Kettern

1

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22 August 2017

Michael Dreiseidler

series ordinal

2

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22 August 2017

Riga Tawo

series ordinal

3

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22 August 2017

Jörg Höhfeld

series ordinal

4

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22 August 2017

1 May 2010

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22 August 2017

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22 August 2017

391

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22 August 2017

481-489

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22 August 2017

5

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An intralysosomal hsp70 is required for a selective pathway of lysosomal protein degradation

22 August 2017

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

To be, or not to be--molecular chaperones in protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Chaperone-assisted selective autophagy is essential for muscle maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The heat shock protein 90 chaperone complex: an evolving therapeutic target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Functional interactions of tau and their relevance for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The Hsp70 and Hsp60 chaperone machines

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

A receptor for the selective uptake and degradation of proteins by lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

CHIP activates HSF1 and confers protection against apoptosis and cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Regulation of the cytoplasmic quality control protein degradation pathway by BAG2

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Autophagy: a lysosomal degradation pathway with a central role in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The synaptic vesicle protein CSP alpha prevents presynaptic degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The sarcomeric Z-disc: a nodal point in signalling and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Folding of newly translated proteins in vivo: the role of molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Converging concepts of protein folding in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

VMA21 deficiency: a case of myocyte indigestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

BAG3 deficiency results in fulminant myopathy and early lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Integrin binding immunoglobulin type filamin domains have variable stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

BAG5 inhibits parkin and enhances dopaminergic neuron degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Lysosome membrane lipid microdomains: novel regulators of chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

N-terminal strands of filamin Ig domains act as a conformational switch under biological forces

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Activation of chaperone-mediated autophagy during oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

A role for ubiquitin in selective autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Lysosomal myopathies: an excessive build-up in autophagosomes is too much to handle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Chaperone-mediated autophagy in aging and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The ubiquitin ligase E6-AP is induced and recruited to aggresomes in response to proteasome inhibition and may be involved in the ubiquitination of Hsp70-bound misfolded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

CHIP deletion reveals functional redundancy of E3 ligases in promoting degradation of both signaling proteins and expanded glutamine proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Filamins: promiscuous organizers of the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Biological and chemical approaches to diseases of proteostasis deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

RETRACTED: VMA21 deficiency causes an autophagic myopathy by compromising V-ATPase activity and lysosomal acidification

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The roles of intracellular protein-degradation pathways in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Cysteine string protein promotes proteasomal degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) by increasing its interaction with the C terminus of Hsp70-interacting protein and promoting CFTR ubiquitylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

The folding pathway of a fast-folding immunoglobulin domain revealed by single-molecule mechanical experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Mutation in BAG3 causes severe dominant childhood muscular dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Autophagy, organelles and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

A mutation in the dimerization domain of filamin c causes a novel type of autosomal dominant myofibrillar myopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

HSJ1 is a neuronal shuttling factor for the sorting of chaperone clients to the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Autophagosome formation: core machinery and adaptations

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Autophagy: molecular machinery for self-eating

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Pathways of chaperone-mediated protein folding in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Structural and functional coupling of Hsp90- and Sgt1-centred multi-protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

Paralysis and early death in cysteine string protein mutants of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2010.058

21 January 2018

Identifiers

DOI

10.1515/BC.2010.058

1 reference

release_ubz7dxadwvf5hh2ex2hjg36z44

22 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ubz7dxadwvf5hh2ex2hjg36z44

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference