Polycystins and renovascular mechanosensory transduction (Q37772076)

22 August 2017

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title

Polycystins and renovascular mechanosensory transduction (English)

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22 August 2017

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Amanda Patel

1

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PubMed ID

20625375

22 August 2017

Eric Honoré

series ordinal

2

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PubMed ID

20625375

22 August 2017

language of work or name

English

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publication date

13 July 2010

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Nature Reviews Nephrology

22 August 2017

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22 August 2017

6

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22 August 2017

9

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22 August 2017

530-538

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https://scigraph.springernature.com/pub.10.1038/nrneph.2010.97

22 August 2017

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cites work

Polycystins: from mechanosensation to gene regulation

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Polycystins and primary cilia: primers for cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Polycystins: polymodal receptor/ion-channel cellular sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

TRP channels as cellular sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Polycystins and mechanosensation in renal and nodal cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Ciliary polycystin-2 is a mechanosensitive calcium channel involved in nitric oxide signaling cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Two populations of node monocilia initiate left-right asymmetry in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

The ion channel polycystin-2 is required for left-right axis determination in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

When cilia go bad: cilia defects and ciliopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Cilia and centrosomes: a unifying pathogenic concept for cystic kidney disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

The Ciliopathies: An Emerging Class of Human Genetic Disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Bending the MDCK cell primary cilium increases intracellular calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

A physiological view of the primary cilium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Removal of the MDCK cell primary cilium abolishes flow sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

The remarkable mechanical strength of polycystin-1 supports a direct role in mechanotransduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

The nanomechanics of polycystin-1 extracellular region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

TRPP2 and TRPV4 form a polymodal sensory channel complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Specific association of the gene product of PKD2 with the TRPC1 channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

TRPC1 forms the stretch-activated cation channel in vertebrate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Defective planar cell polarity in polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Cardiac defects and renal failure in mice with targeted mutations in Pkd2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Lack of a laterality phenotype in Pkd1 knock-out embryos correlates with absence of polycystin-1 in nodal cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Situs inversus in Dpcd/Poll-/-, Nme7-/- , and Pkd1l1-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Cardiovascular polycystins: insights from autosomal dominant polycystic kidney disease and transgenic animal models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Cardiovascular abnormalities in autosomal-dominant polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Modifier effect of ENOS in autosomal dominant polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Mechanotransduction in vascular physiology and atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

PKD1 haploinsufficiency is associated with altered vascular reactivity and abnormal calcium signaling in the mouse aorta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Polycystin-2 is an intracellular calcium release channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Released nucleotides amplify the cilium-dependent, flow-induced [Ca2+]i response in MDCK cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Loss of apical monocilia on collecting duct principal cells impairs ATP secretion across the apical cell surface and ATP-dependent and flow-induced calcium signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Fluid flow sensing and triggered nucleotide release in epithelia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Control of epithelial transport via luminal P2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

P2 receptors in the regulation of renal transport mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Physiology and pathophysiology of purinergic neurotransmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Impaired flow-dependent control of vascular tone and remodeling in P2X4-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Transepithelial pressure pulses induce nucleotide release in polarized MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Exploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Purinergic signaling in the lumen of a normal nephron and in remodeled PKD encapsulated cysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Filamins as integrators of cell mechanics and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Transport function of the naturally occurring pathogenic polycystin-2 mutant, R742X.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

ATP release from non-excitable cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

The transient receptor potential channels TRPP2 and TRPC1 form a heterotetramer with a 2:2 stoichiometry and an alternating subunit arrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Structural and molecular basis of the assembly of the TRPP2/PKD1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Purinergic signalling: ATP release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Polycystin-1 and -2 Dosage Regulates Pressure Sensing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Mechanoregulation of intracellular Ca2+ in human autosomal recessive polycystic kidney disease cyst-lining renal epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Somatic inactivation of Pkd2 results in polycystic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Analysis of the polycystins in aortic vascular smooth muscle cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Hydrostatic pressure within renal cysts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Cystic changes in fetal kidneys following ureteral ligation: Studies by microdissection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Flow-induced [Ca2+]i increase depends on nucleotide release and subsequent purinergic signaling in the intact nephron

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

Intraluminal autocrine purinergic signaling within cysts: implications for the progression of diseases that involve encapsulated cyst formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.97

ATP release mechanisms in primary cultures of epithelia derived from the cysts of polycystic kidneys.

31 March 2020

1 reference

12 December 2020

Vascular expression of polycystin.

1 reference

12 December 2020

Vascular expression of polycystin-2.

1 reference

12 December 2020

Revisiting TRPC1 and TRPC6 mechanosensitivity.

1 reference

12 December 2020

Arteriolar myogenic signalling mechanisms: Implications for local vascular function

1 reference

12 December 2020

An in vitro test of the cell stretch-proliferation hypothesis of renal cyst enlargement

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2010.97

1 reference

22 August 2017

1 reference

PubMed ID

20625375