Inverse Agonism at Serotonin and Cannabinoid Receptors (Q37778511)

23 August 2017

1 reference

title

Inverse agonism at serotonin and cannabinoid receptors (English)

1 reference

23 August 2017

Inverse Agonism at Serotonin and Cannabinoid Receptors (English)

1 reference

https://api.crossref.org/works/10.1016/S1877-1173(10)91001-6

18 June 2024

0 references

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cannabinoid receptor agonists

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691957

18 June 2024

3

William P. Clarke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691957

18 June 2024

author name string

Umberto Spampinato

4

1 reference

23 August 2017

Vincent J. Aloyo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691957

18 June 2024

Kelly A. Berg

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691957

18 June 2024

John A. Harvey

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691957

18 June 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20691957

18 June 2024

publication date

1 January 2010

1 reference

Progress in Molecular Biology and Translational Science

23 August 2017

published in

1 reference

23 August 2017

volume

91

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23 August 2017

page(s)

1-40

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

23 August 2017

1 reference

7 January 2021

Role of the serotonin 5-HT(2A) receptor in learning

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Molecular biology of 5-HT receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

The mammalian beta 2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

G protein-coupled receptor allosterism and complexing

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

The two-state model of receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

A three-state receptor model of agonist action

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

h5-HT(1B) receptor-mediated constitutive Galphai3-protein activation in stably transfected Chinese hamster ovary cells: an antibody capture assay reveals protean efficacy of 5-HT

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Evidence for protean agonism of RX 831003 at alpha 2A-adrenoceptors by co-expression with different G alpha protein subunits

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Inverse, protean, and ligand-selective agonism: matters of receptor conformation

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Missing links: mechanisms of protean agonism

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Multiple signaling states of G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Considerations in the evaluation of inverse agonism and protean agonism at G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Inhibition of the constitutive activity of human 5-HT1A receptors by the inverse agonist, spiperone but not the neutral antagonist, WAY 100,635

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Agonist and inverse agonist efficacy at human recombinant serotonin 5-HT1A receptors as a function of receptor:G-protein stoichiometry

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Enhanced detection of receptor constitutive activity in the presence of regulators of G protein signaling: applications to the detection and analysis of inverse agonists and low-efficacy partial agonists

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Agonist-independent activation of Gz by the 5-hydroxytryptamine1A receptor co-expressed in Spodoptera frugiperda cells. Distinguishing inverse agonists from neutral antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Mechanisms of agonism and inverse agonism at serotonin 5-HT1A receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

The putative <<silent>> 5-HT(1A) receptor antagonist, WAY 100635, has inverse agonist properties at cloned human 5-HT(1A) receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Agonist, antagonist, and inverse agonist properties of antipsychotics at human recombinant 5-HT(1A) receptors expressed in HeLa cells

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Differential modulation by GTPgammaS of agonist and inverse agonist binding to h5-HT(1A) receptors revealed by [3H]-WAY100,635

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Differential effects of the 5-hydroxytryptamine (5-HT)1A receptor inverse agonists Rec 27/0224 and Rec 27/0074 on electrophysiological responses to 5-HT1A receptor activation in rat dorsal raphe nucleus and hippocampus in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Pharmacological characterisation of a cloned dog 5-HT1B receptor cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

SB-236057, a selective 5-HT1B receptor inverse agonist, blocks the 5-HT human terminal autoreceptor

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

The effect of SB-236057-A, a selective 5-HT1B receptor inverse agonist, on in vivo extracellular 5-HT levels in the freely-moving guinea-pig

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Inverse agonism and constitutive activity as functional correlates of serotonin h5-HT(1B) receptor/G-protein stoichiometry

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Could the 5-HT1B receptor inverse agonism affect learning consolidation?

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

SB-236057-A: a selective 5-HT1B receptor inverse agonist

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

5-HT 1B/D receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Constitutive activity at serotonin 5-HT(1D) receptors: detection by homologous GTPgammaS versus [(35)S]-GTPgammaS binding isotherms.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Inverse agonist properties of antipsychotic agents at cloned, human (h) serotonin (5-HT)(1B) and h5-HT(1D) receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Creation of a constitutively activated state of the 5-HT2A receptor by site-directed mutagenesis: revelation of inverse agonist activity of antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Pimavanserin tartrate: a 5-HT2A inverse agonist with potential for treating various neuropsychiatric disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Functional reconstitution in situ of 5-hydroxytryptamine2c (5HT2c) receptors with alphaq and inverse agonism of 5HT2c receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Deramciclane, a putative anxiolytic drug, is a serotonin 5-HT2C receptor inverse agonist but fails to induce 5-HT2C receptor down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Biarylcarbamoylindolines are novel and selective 5-HT(2C) receptor inverse agonists: identification of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a potential antidepressant/anxiolytic agent

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile: lack of tolerance and withdrawal anxiety

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Sertindole is a serotonin 5-HT2c inverse agonist and decreases agonist but not antagonist binding to 5-HT2c receptors after chronic treatment

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

5-HT4 receptors: gene, transduction and effects on olfactory memory.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

The human 5-HT7 serotonin receptor splice variants: constitutive activity and inverse agonist effects

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Differential inverse agonist efficacies of SB-258719, SB-258741 and SB-269970 at human recombinant serotonin 5-HT7 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Differential profile of typical, atypical and third generation antipsychotics at human 5-HT7a receptors coupled to adenylyl cyclase: detection of agonist and inverse agonist properties.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Reanalysis of constitutively active rat and human 5-HT7(a) receptors in HEK-293F cells demonstrates lack of silent properties for reported neutral antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Expression and function of 5-HT7 receptors in smooth muscle preparations from equine duodenum, ileum, and pelvic flexure

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Serotonin2C receptor localization in GABA neurons of the rat medial prefrontal cortex: implications for understanding the neurobiology of addiction

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

5-Hydroxytryptamine2-family receptors (5-hydroxytryptamine2A, 5-hydroxytryptamine2B, 5-hydroxytryptamine2C): where structure meets function

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Evidence for a model of agonist-induced activation of 5-hydroxytryptamine 2A serotonin receptors that involves the disruption of a strong ionic interaction between helices 3 and 6.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

The role of serotonin in antipsychotic drug action

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Serotonergic regulation of associative learning

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Serotonin function in anxiety. II. Effects of the serotonin agonist MCPP in panic disorder patients and healthy subjects

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Anxiogenic effects of m-CPP in patients with panic disorder: comparison to caffeine's anxiogenic effects

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Effect of SB 200646A, a 5-HT2C/5-HT2B receptor antagonist, in two conflict models of anxiety.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Anxiety-like effects induced by acute fluoxetine, sertraline or m-CPP treatment are reversed by pretreatment with the 5-HT2C receptor antagonist SB-242084 but not the 5-HT1A receptor antagonist WAY-100635.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Differences in agonist-independent activity of 5-Ht2A and 5-HT2c receptors revealed by heterologous expression

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Dissociable effects of selective 5-HT2A and 5-HT2C receptor antagonists on serial spatial reversal learning in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Opposing roles for 5-HT2A and 5-HT2C receptors in the nucleus accumbens on inhibitory response control in the 5-choice serial reaction time task.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Therapeutic potential of 5-HT2C receptor antagonists in the treatment of anxiety disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Assessment of binding affinity to 5-hydroxytryptamine 2A (5-HT2A) receptor and inverse agonist activity of naftidrofuryl: comparison with those of sarpogrelate

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Constitutive activity of G-protein coupled receptors: emphasis on serotonin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: implications for serotonergic signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Differential effects of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxyl]-5-pyridyl]carbamoyl]-6-trifluoromethylindone (SB 243213) on 5-hydroxytryptamine(2C) receptor-mediated responses

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Desensitization of G protein-coupled receptors and neuronal functions

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Messenger RNA editing of the human serotonin 5-HT2C receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Regulation of serotonin-2C receptor G-protein coupling by RNA editing

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

A conservative, single-amino acid substitution in the second cytoplasmic domain of the human Serotonin2C receptor alters both ligand-dependent and -independent receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

How receptors talk to trimeric G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Functional and structural complexity of signal transduction via G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Molecular basis of receptor/G-protein-coupling selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Altered G protein-coupling functions of RNA editing isoform and splicing variant serotonin2C receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Ligand-induced overexpression of a constitutively active beta2-adrenergic receptor: pharmacological creation of a phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Single-unit activity in the dorsomedial prefrontal cortex during the expression of discriminative bradycardia in rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Sequence of single neuron changes in CA1 hippocampus of rabbits during acquisition of trace eyeblink conditioned responses

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Lesions of the caudal area of rabbit medial prefrontal cortex impair trace eyeblink conditioning

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Classical conditioning and brain systems: the role of awareness

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Conditioning, awareness, and the hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Variations in CS associability and multiple unit hippocampal activity in the rabbit

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Antagonist binding at 5-HT(2A) and 5-HT(2C) receptors in the rabbit: high correlation with the profile for the human receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Effects of LSD-25 on classical trace conditioning

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Effects of LSD, ritanserin, 8-OH-DPAT, and lisuride on classical conditioning in the rabbit.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Dissociable effects of the 5-HT(2) antagonist mianserin on associative learning and performance in the rabbit.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Effects of serotonin 5-HT(2A/2C) antagonists on associative learning in the rabbit

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

MDMA enhances associative and nonassociative learning in the rabbit.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. III. Agonist and antagonist properties at serotonin, 5-HT(1) and 5-HT(2), receptor subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Pharmacological characterization of 8-OH-DPAT-induced inhibition of rat hippocampal 5-HT release in vivo as measured by microdialysis

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Effect of serotonin depletion on 5-HT2A-mediated learning in the rabbit: evidence for constitutive activity of the 5-HT2A receptor in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Effect of 5-HT2 receptor antagonists on a cranial nerve reflex in the rabbit: evidence for inverse agonism

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Effects of LSD on classical conditioning as a function of CS-UCS interval: relationship to reflex facilitation.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

Serotonin(2C) receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: a combined dialysis and electrophysiological analysis in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2991001-6

7 January 2021

The nigrostriatal dopamine system: a neglected target for 5-HT2C receptors

1 reference

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7 January 2021

Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors

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7 January 2021

Clozapine and haloperidol differentially alter the constitutive activity of central serotonin2C receptors in vivo

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7 January 2021

In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: differential effects of inverse agonist versus antagonist

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7 January 2021

Region-dependent regulation of mesoaccumbens dopamine neurons in vivo by the constitutive activity of central serotonin2C receptors

1 reference

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7 January 2021

Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine

1 reference

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7 January 2021

Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens

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7 January 2021

Physiological relevance of constitutive activity of 5-HT2A and 5-HT2C receptors

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7 January 2021

Historical review: Negative efficacy and the constitutive activity of G-protein-coupled receptors.

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7 January 2021

Serotonin and psychostimulant addiction: focus on 5-HT1A-receptors

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7 January 2021

Inverse agonism: from curiosity to accepted dogma, but is it clinically relevant?

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7 January 2021

Fine-tuning serotonin2c receptor function in the brain: molecular and functional implications

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7 January 2021

Physiological and therapeutic relevance of constitutive activity of 5-HT 2A and 5-HT 2C receptors for the treatment of depression

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7 January 2021

Pimavanserin, a serotonin(2A) receptor inverse agonist, for the treatment of parkinson's disease psychosis

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7 January 2021

Cannabinoids for clinicians: the rise and fall of the cannabinoid antagonists

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7 January 2021

Focus on the three key enzymes hydrolysing endocannabinoids as new drug targets

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7 January 2021

Agonist selective regulation of G proteins by cannabinoid CB(1) and CB(2) receptors

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7 January 2021

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

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7 January 2021

A Selective Inverse Agonist for Central Cannabinoid Receptor Inhibits Mitogen-activated Protein Kinase Activation Stimulated by Insulin or Insulin-like Growth Factor 1

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7 January 2021

SR 141716A acts as an inverse agonist to increase neuronal voltage-dependent Ca2+ currents by reversal of tonic CB1 cannabinoid receptor activity

1 reference

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7 January 2021

Antiobesity efficacy of a novel cannabinoid-1 receptor inverse agonist, N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[[5-(trifluoromethyl)pyridin-2-yl]oxy]propanamide (MK-0364), in rodents

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7 January 2021

Hemopressin is an inverse agonist of CB1 cannabinoid receptors

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7 January 2021

Changes in body temperature and oxygen consumption rate of conscious mice produced by intrahypothalamic and intracerebroventricular injections of delta 9-tetrahydrocannabinol

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7 January 2021

A neutral CB1 receptor antagonist reduces weight gain in rat.

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7 January 2021

The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats

1 reference

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7 January 2021

N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) interaction with LYS 3.28(192) is crucial for its inverse agonism at the cannabinoid CB1 receptor

1 reference

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7 January 2021

Biarylpyrazole inverse agonists at the cannabinoid CB1 receptor: importance of the C-3 carboxamide oxygen/lysine3.28(192) interaction.

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7 January 2021

6"-Azidohex-2"-yne-cannabidiol: a potential neutral, competitive cannabinoid CB1 receptor antagonist

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7 January 2021

Inverse agonism and neutral antagonism at cannabinoid CB1 receptors

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7 January 2021

Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors

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7 January 2021

Appetite suppression and weight loss after the cannabinoid antagonist SR 141716.

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7 January 2021

Synergistic effects of cannabinoid inverse agonist AM251 and opioid antagonist nalmefene on food intake in mice

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7 January 2021

CB1 cannabinoid receptor-mediated modulation of food intake in mice

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7 January 2021

Aminopyrazine CB1 receptor inverse agonists

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7 January 2021

Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial

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7 January 2021

Long-term effect of CB1 blockade with rimonabant on cardiometabolic risk factors: two year results from the RIO-Europe Study

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7 January 2021

Long term pharmacotherapy for obesity and overweight: updated meta-analysis.

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7 January 2021

Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials

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7 January 2021

The future of endocannabinoid-oriented clinical research after CB1 antagonists.

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7 January 2021

Suppression of feeding, drinking, and locomotion by a putative cannabinoid receptor 'silent antagonist'.

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7 January 2021

Cannabinoid receptor antagonists: pharmacological opportunities, clinical experience, and translational prognosis

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7 January 2021

Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response

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7 January 2021

Is prenalterol (H133/80) really a selective beta 1 adrenoceptor agonist? Tissue selectivity resulting from differences in stimulus-response relationships

9

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5-hydroxytryptamine2A receptor inverse agonists as antipsychotics

18 June 2024

45

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Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors

18 June 2024

52

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Serotonin function in anxiety

18 June 2024

75

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5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential

18 June 2024

78

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5-Hydroxytryptamine2 receptors coupled to phospholipase C in rat aorta: modulation of phosphoinositide turnover by phorbol ester

18 June 2024

82

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Signal transduction differences between 5-hydroxytryptamine type 2A and type 2C receptor systems

18 June 2024

83

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Differences in rapid desensitization of 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptor-mediated phospholipase C activation

18 June 2024

84

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Increased basal phosphorylation of the constitutively active serotonin 2C receptor accompanies agonist-mediated desensitization

18 June 2024

101

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Effects of LSD on learning as measured by classical conditioning of the rabbit nictitating membrane response

18 June 2024

121

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18 June 2024

Identifiers

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23 August 2017

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