What's the hype about CDK5RAP2? (Q37843832)

24 August 2017

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title

What's the hype about CDK5RAP2? (English)

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24 August 2017

6

Angela M Kaindl

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24 August 2017

Nadine Kraemer

1

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24 August 2017

Lina Issa

2

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24 August 2017

Stefanie C R Hauck

3

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24 August 2017

Shyamala Mani

4

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24 August 2017

Olaf Ninnemann

5

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24 August 2017

17 February 2011

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Cellular and Molecular Life Sciences

24 August 2017

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24 August 2017

68

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24 August 2017

1719-1736

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24 August 2017

10

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https://scigraph.springernature.com/pub.10.1007/s00018-011-0635-4

24 August 2017

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cites work

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro

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https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cloning of three novel neuronal Cdk5 activator binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Identification of a common protein association region in the neuronal Cdk5 activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Identification and structure characterization of a Cdk inhibitory peptide derived from neuronal-specific Cdk5 activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Novel meiosis-specific isoform of mammalian SMC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Molecular evolution of the brain size regulator genes CDK5RAP2 and CENPJ

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

SMC proteins and chromosome mechanics: from bacteria to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Predicting coiled coils from protein sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cdk5 activator-binding protein C53 regulates apoptosis induced by genotoxic stress via modulating the G2/M DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Tumor suppressor protein C53 antagonizes checkpoint kinases to promote cyclin-dependent kinase 1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

CDK5RAP2 regulates centriole engagement and cohesion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

An unusual member of the Cdk family: Cdk5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Role of cyclin-dependent kinase 5 and its activator P35 in local axon and growth cone stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cyclin-dependent kinase 5 activity regulates pain signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cortical interneurons require p35/Cdk5 for their migration and laminar organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A third novel locus for primary autosomal recessive microcephaly maps to chromosome 9q34.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Identification of microcephalin, a protein implicated in determining the size of the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Primary autosomal recessive microcephaly (MCPH1) maps to chromosome 8p22-pter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The second locus for autosomal recessive primary microcephaly (MCPH2) maps to chromosome 19q13.1-13.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

WDR62 is associated with the spindle pole and is mutated in human microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Primary autosomal recessive microcephaly: homozygosity mapping of MCPH4 to chromosome 15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A fifth locus for primary autosomal recessive microcephaly maps to chromosome 1q31.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

ASPM mutations identified in patients with primary microcephaly and seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A novel locus for autosomal recessive primary microcephaly (MCPH6) maps to 13q12.2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mutations in STIL, encoding a pericentriolar and centrosomal protein, cause primary microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Expanding the clinical and neuroradiologic phenotype of primary microcephaly due to ASPM mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Maintaining the proper connection between the centrioles and the pericentriolar matrix requires Drosophila centrosomin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Centrosome control of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Proper recruitment of gamma-tubulin and D-TACC/Msps to embryonic Drosophila centrosomes requires Centrosomin Motif 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Zygotic development without functional mitotic centrosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Making microtubules and mitotic spindles in cells without functional centrosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The centrosome in vertebrates: more than a microtubule-organizing center

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Centrosome composition and microtubule anchoring mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Microtubule-organizing centres: a re-evaluation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The centrosome in higher organisms: structure, composition, and duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mitosis-specific anchoring of gamma tubulin complexes by pericentrin controls spindle organization and mitotic entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

CDK5RAP2 is required for spindle checkpoint function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The spindle-assembly checkpoint in space and time

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Ubiquitin ligases: cell-cycle control and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

CLIPs and CLASPs and cellular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mitotic spindle regulation by Nde1 controls cerebral cortical size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Neurabin-I is phosphorylated by Cdk5: implications for neuronal morphogenesis and cortical migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Neuronal morphogenesis is regulated by the interplay between cyclin-dependent kinase 5 and the ubiquitin ligase mind bomb 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cyclin-dependent kinase 5 and neuronal migration in the neocortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A novel disruption of cortical development in p35(-/-) mice distinct from reeler.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Transcriptional regulation of cortical neuron migration by POU domain factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Positive selection in ASPM is correlated with cerebral cortex evolution across primates but not with whole-brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Evolution. Are human brains still evolving? Brain genes show signs of selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Bruce Lahn profile. Links between brain genes, evolution, and cognition challenged.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

BRUCE LAHN PROFILE: Brain Man Makes Waves With Claims of Recent Human Evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Cytoskeletal genes regulating brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Comment on "Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens" and "Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans".

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Microcephalin, a Gene Regulating Brain Size, Continues to Evolve Adaptively in Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

The spread of alphabetical writing may have favored the latest variant of the ASPM gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Accelerated evolution of the ASPM gene controlling brain size begins prior to human brain expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Evolution of primary microcephaly genes and the enlargement of primate brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A novel domain suggests a ciliary function for ASPM, a brain size determining gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Genetic, physiologic and ecogeographic factors contributing to variation in Homo sapiens: Homo floresiensis reconsidered

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Evolutionary Genetics: is brain evolution still continuing in modern humans?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

A common SNP of MCPH1 is associated with cranial volume variation in Chinese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Molecular evolution of microcephalin, a gene determining human brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Genetic links between brain development and brain evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Sex-dependent association of common variants of microcephaly genes with brain structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0635-4

Many roads lead to primary autosomal recessive microcephaly

21 January 2018

1 reference

12 December 2020

[Study of a familial case of microcephaly and micrencephaly. Clinical and anatomo-pathologic considerations on a preliminary basis]

1 reference

12 December 2020

Taxanes, microtubules and chemoresistant breast cancer.

1 reference

12 December 2020

Evolution of the human ASPM gene, a major determinant of brain size

1 reference

12 December 2020

[Familial microcephalies due to cerebral malformation. Anatomical and clinical study]

1 reference

12 December 2020

Migration defects of cdk5(-/-) neurons in the developing cerebellum is cell autonomous

1 reference

12 December 2020

Pacing below the ventricular rate in terminating ventricular tachycardia and flutter

1 reference

12 December 2020

Layering defect in p35 deficiency is linked to improper neuronal-glial interaction in radial migration

1 reference

12 December 2020

Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex

1 reference

12 December 2020

Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics

1 reference

12 December 2020

CEP215 is involved in the dynein-dependent accumulation of pericentriolar matrix proteins for spindle pole formation

1 reference

12 December 2020

The centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila.

1 reference

12 December 2020

10.1007/S00018-011-0635-4

Identifiers

DOI

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24 August 2017

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