Early inhibitors of human cytomegalovirus: state-of-art and therapeutic perspectives (Q37875379)

24 August 2017

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title

Early inhibitors of human cytomegalovirus: state-of-art and therapeutic perspectives (English)

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24 August 2017

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4

Arianna Loregian

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24 August 2017

3

Giorgio Palù

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24 August 2017

Beatrice Mercorelli

1

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PubMed ID

21570424

24 August 2017

David Lembo

series ordinal

2

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PubMed ID

21570424

24 August 2017

language of work or name

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28 April 2011

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Pharmacology & Therapeutics

24 August 2017

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24 August 2017

131

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24 August 2017

3

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24 August 2017

309-329

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Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoter

24 August 2017

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12 December 2020

New cell-based indicator assays for the detection of human cytomegalovirus infection and screening of inhibitors of viral immediate-early 2 protein activity.

1 reference

12 December 2020

HIV-1 entry inhibitors: an overview

1 reference

12 December 2020

Lactoferrin: a general review.

1 reference

12 December 2020

Synthesis of stilbene derivatives with inhibition of SARS coronavirus replication.

1 reference

12 December 2020

N-terminal stretch Arg2, Arg3, Arg4 and Arg5 of human lactoferrin is essential for binding to heparin, bacterial lipopolysaccharide, human lysozyme and DNA

1 reference

12 December 2020

Synergistic inhibition of HIV-1 in activated and resting peripheral blood mononuclear cells, monocyte-derived macrophages, and selected drug-resistant isolates with nucleoside analogues combined with a natural product, resveratrol

1 reference

12 December 2020

Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates

1 reference

12 December 2020

A potent peptidomimetic inhibitor of HSV ribonucleotide reductase with antiviral activity in vivo

1 reference

12 December 2020

Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functions

1 reference

12 December 2020

Human cytomegalovirus DNA replication: antiviral targets and drugs

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12 December 2020

Human cytomegalovirus protein pp71 displaces the chromatin-associated factor ATRX from nuclear domain 10 at early stages of infection

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12 December 2020

Human cytomegalovirus contains a tegument protein that enhances transcription from promoters with upstream ATF and AP-1 cis-acting elements

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12 December 2020

Progressive disease due to ganciclovir-resistant cytomegalovirus in immunocompromised patients

1 reference

12 December 2020

Resveratrol inhibition of herpes simplex virus replication

1 reference

12 December 2020

Sulfated polymers inhibit the interaction of human cytomegalovirus with cell surface heparan sulfate

1 reference

12 December 2020

Antiviral effects of milk proteins: acylation results in polyanionic compounds with potent activity against human immunodeficiency virus types 1 and 2 in vitro

1 reference

12 December 2020

The human cytomegalovirus IE2 86-kilodalton protein interacts with an early gene promoter via site-specific DNA binding and protein-protein associations

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12 December 2020

Transmission of maternal cytomegalovirus-specific immunity in the guinea pig

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12 December 2020

Geldanamycin, a potent and specific inhibitor of Hsp90, inhibits gene expression and replication of human cytomegalovirus

1 reference

12 December 2020

Temporal dynamics of cytomegalovirus chromatin assembly in productively infected human cells

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12 December 2020

Findings and conclusions from CMV hyperimmune globulin treatment trials

1 reference

12 December 2020

Two gamma interferon-activated site-like elements in the human cytomegalovirus major immediate-early promoter/enhancer are important for viral replication.

1 reference

12 December 2020

Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses.

1 reference

12 December 2020

State of the art and perspectives for the delivery of antisense oligonucleotides and siRNA by polymeric nanocarriers.

1 reference

12 December 2020

Proteasome-dependent, ubiquitin-independent degradation of Daxx by the viral pp71 protein in human cytomegalovirus-infected cells

1 reference

12 December 2020

The human cytomegalovirus major immediate-early distal enhancer region is required for efficient viral replication and immediate-early gene expression

1 reference

12 December 2020

Sulfated derivatives of Escherichia coli K5 capsular polysaccharide are potent inhibitors of human cytomegalovirus

1 reference

12 December 2020

New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection

1 reference

12 December 2020

Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes

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12 December 2020

Localization of human cytomegalovirus in peripheral blood leukocytes by in situ hybridization.

1 reference

12 December 2020

Effect of passive antibody on congenital cytomegalovirus infection in guinea pigs

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12 December 2020

Initiation of human cytomegalovirus infection requires initial interaction with cell surface heparan sulfate

1 reference

12 December 2020

Calcium spirulan, an inhibitor of enveloped virus replication, from a blue-green alga Spirulina platensis

1 reference

12 December 2020

New anti-human immunodeficiency virus type 1 6-aminoquinolones: mechanism of action

1 reference

12 December 2020

CpG oligodeoxynucleotides block human immunodeficiency virus type 1 replication in human lymphoid tissue infected ex vivo

1 reference

12 December 2020

Lactoferrin and the inflammatory response

1 reference

12 December 2020

The promoter-regulatory region of the major immediate-early gene of human cytomegalovirus responds to T-lymphocyte stimulation and contains functional cyclic AMP-response elements

1 reference

12 December 2020

Artemisinin: large community studies.

1 reference

12 December 2020

Antiviral activities of lactoferrin

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12 December 2020

Pathogenesis of human cytomegalovirus infection and cellular targets

1 reference

12 December 2020

Artesunate for the treatment of severe falciparum malaria

1 reference

12 December 2020

Lactoferrin, lactoferrin receptors and iron metabolism.

1 reference

12 December 2020

Structure, composition and heparin binding properties of a human cytomegalovirus glycoprotein complex designated gC-II

1 reference

12 December 2020

CMV-hyperimmune globulin for preventing cytomegalovirus infection and disease in solid organ transplant recipients: a meta-analysis.

1 reference

12 December 2020

The multi-targeted kinase inhibitor sorafenib inhibits human cytomegalovirus replication.

1 reference

12 December 2020

Human cytomegalovirus immediate early interaction with host nuclear structures: definition of an immediate transcript environment

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12 December 2020

Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion

1 reference

12 December 2020

The putative zinc finger of the human cytomegalovirus IE2 86-kilodalton protein is dispensable for DNA binding and autorepression, thereby demarcating a concise core domain in the C terminus of the protein

1 reference

12 December 2020

Inhibition of herpes simplex virus types 1 and 2 in vitro infection by sulfated derivatives of Escherichia coli K5 polysaccharide

1 reference

12 December 2020

Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease.

1 reference

12 December 2020

Antiviral activities of biflavonoids

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12 December 2020

A cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication

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12 December 2020

Protection of Balb/c mice against infection with FMDV by immunostimulation with CpG oligonucleotides

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12 December 2020

Characterization of the human cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells.

1 reference

12 December 2020

Disruption of protein-protein interactions: towards new targets for chemotherapy

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12 December 2020

Proteasome-dependent, ubiquitin-independent degradation of the Rb family of tumor suppressors by the human cytomegalovirus pp71 protein

1 reference

12 December 2020

Therapeutic potential of Toll-like receptor 9 activation

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12 December 2020

Genetic content of wild-type human cytomegalovirus.

1 reference

12 December 2020

Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice

1 reference

12 December 2020

Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships

1 reference

12 December 2020

Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia

1 reference

12 December 2020

Anticytomegalovirus activity of pristimerin, a triterpenoid quinone methide isolated from Maytenus heterophylla (Eckl. & Zeyh.).

1 reference

12 December 2020

Dynamic histone H3 acetylation and methylation at human cytomegalovirus promoters during replication in fibroblasts

1 reference

12 December 2020

Cytomegalovirus infections of the nervous system

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12 December 2020

Potent antiviral activity of an antisense oligonucleotide complementary to the intron-exon boundary of human cytomegalovirus genes UL36 and UL37

1 reference

12 December 2020

Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region

1 reference

12 December 2020

A human cytomegalovirus glycoprotein complex designated gC-II is a major heparin-binding component of the envelope

1 reference

12 December 2020

Dietary flavonoids induce MLL translocations in primary human CD34+ cells

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12 December 2020

Specific inhibition of human cytomegalovirus glycoprotein B-mediated fusion by a novel thiourea small molecule

1 reference

12 December 2020

Regulated diversity of heparan sulfate

1 reference

12 December 2020

Effect of human milk prostaglandins and lactoferrin on respiratory syncytial virus and rotavirus

1 reference

12 December 2020

Evaluation of the antiviral activity of kaempferol and its glycosides against human cytomegalovirus

1 reference

12 December 2020

Human cytomegalovirus tropism for endothelial/epithelial cells: scientific background and clinical implications

1 reference

12 December 2020

In vitro anti-herpetic activity of sulfated polysaccharide fractions from Caulerpa racemosa

1 reference

12 December 2020

Foscarnet. A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with viral infections

1 reference

12 December 2020

Prophylaxis of acute respiratory virus infections using nucleic acid-based drugs.

1 reference

12 December 2020

Inhibition of cytomegalovirus infection by lactoferrin in vitro and in vivo

1 reference

12 December 2020

The RAF proteins take centre stage

1 reference

12 December 2020

The human cytomegalovirus major immediate-early enhancer determines the efficiency of immediate-early gene transcription and viral replication in permissive cells at low multiplicity of infection

1 reference

12 December 2020

2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections

1 reference

12 December 2020

A natural sulfated polysaccharide, calcium spirulan, isolated from Spirulina platensis: in vitro and ex vivo evaluation of anti-herpes simplex virus and anti-human immunodeficiency virus activities

1 reference

12 December 2020

Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro

1 reference

12 December 2020

Human cytomegalovirus IE86 attenuates virus- and tumor necrosis factor alpha-induced NFkappaB-dependent gene expression

1 reference

12 December 2020

Antiviral flavonoids from the seeds of Aesculus chinensis

1 reference

12 December 2020

Human cytomegalovirus up-regulates the phosphatidylinositol 3-kinase (PI3-K) pathway: inhibition of PI3-K activity inhibits viral replication and virus-induced signaling

1 reference

12 December 2020

Functional roles of immediate early proteins encoded by the human cytomegalovirus UL36-38, UL115-119, TRS1/IRS1 and US3 loci

1 reference

12 December 2020

Site-specific binding of the human cytomegalovirus IE2 86-kilodalton protein to an early gene promoter

1 reference

12 December 2020

Therapeutic potential of resveratrol: the in vivo evidence

1 reference

12 December 2020

Cellular repressor inhibits human cytomegalovirus transcription from the UL127 promoter

1 reference

12 December 2020

A phase I study of curdlan sulfate--an HIV inhibitor. Tolerance, pharmacokinetics and effects on coagulation and on CD4 lymphocytes

1 reference

12 December 2020

Specific inhibition of herpes virus replication by receptor-mediated entry of an antiviral peptide linked to Escherichia coli enterotoxin B subunit

1 reference

12 December 2020

Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells

1 reference

12 December 2020

Human cytomegalovirus immediate-early 2 gene expression blocks virus-induced beta interferon production

1 reference

12 December 2020

Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial

1 reference

12 December 2020

Antiviral drugs for cytomegalovirus in transplant recipients: advantages of preemptive therapy

1 reference

12 December 2020

CpG oligodeoxynucleotides protect against the 2009 H1N1 pandemic influenza virus infection in a murine model

1 reference

12 December 2020

Current and potential therapies for the treatment of herpes-virus infections

1 reference

12 December 2020

Inhibition of human cytomegalovirus immediate-early gene expression by an antisense oligonucleotide complementary to immediate-early RNA.

1 reference

12 December 2020

Cytomegalovirus disease in the era of highly active antiretroviral therapy (HAART).

1 reference

12 December 2020

Effect of genistein on replication of bovine herpesvirus type 1.

1 reference

12 December 2020

Metabolic diversity and antiviral activities of acyclic nucleoside phosphonates

1 reference

12 December 2020

Cellular or viral protein binding to a cytomegalovirus promoter transcription initiation site: effects on transcription

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12 December 2020

Charge modification of plasma and milk proteins results in antiviral active compounds

1 reference

12 December 2020

Metabolic engineering of the complete pathway leading to heterologous biosynthesis of various flavonoids and stilbenoids in Saccharomyces cerevisiae.

1 reference

12 December 2020

Review of the biology of Quercetin and related bioflavonoids

1 reference

12 December 2020

Human cytomegalovirus glycoprotein B is required for virus entry and cell-to-cell spread but not for virion attachment, assembly, or egress

1 reference

12 December 2020

Human cytomegalovirus (HCMV) replication kinetics in stem cell transplant recipients following anti-HCMV therapy

1 reference

12 December 2020

PDX1, a cellular homeoprotein, binds to and regulates the activity of human cytomegalovirus immediate early promoter

1 reference

12 December 2020

Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection

1 reference

12 December 2020

Pharmacokinetics, toxicity, and activity of intravenous dextran sulfate in human immunodeficiency virus infection

1 reference

12 December 2020

Plant-derived leading compounds for chemotherapy of human immunodeficiency virus (HIV) infection - an update (1998 - 2007).

1 reference

12 December 2020

Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86

1 reference

12 December 2020

Comparison of vaccine strategies against congenital CMV infection in the guinea pig model

1 reference

12 December 2020

An open randomized comparison of intravenous and intramuscular artesunate in severe falciparum malaria

1 reference

12 December 2020

Rational development of beta-peptide inhibitors of human cytomegalovirus entry

1 reference

12 December 2020

Coiled coils: new structures and new functions

1 reference

12 December 2020

Impact of cytomegalovirus hyperimmune globulin on outcome after cardiothoracic transplantation: a comparative study of combined prophylaxis with CMV hyperimmune globulin plus ganciclovir versus ganciclovir alone

1 reference

12 December 2020

Catalytic inhibition of human DNA topoisomerase II by interactions of grape cell culture polyphenols

1 reference

12 December 2020

Human cytomegalovirus induces cellular tyrosine kinase signaling and promotes glioma cell invasiveness

1 reference

12 December 2020

Anti-herpetic activity of a sulfated xylomannan from Scinaia hatei

1 reference

12 December 2020

Human cytomegalovirus protein pp71 induces Daxx SUMOylation

1 reference

12 December 2020

A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate

1 reference

12 December 2020

Focus on antivirally active sulfated polysaccharides: from structure-activity analysis to clinical evaluation.

1 reference

12 December 2020

Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection

1 reference

12 December 2020

Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleus

1 reference

12 December 2020

Epidermal growth factor receptor is not required for human cytomegalovirus entry or signaling

1 reference

12 December 2020

Expression of a human cytomegalovirus receptor correlates with infectibility of cells

1 reference

12 December 2020

Human cytomegalovirus mutant with sequence-dependent resistance to the phosphorothioate oligonucleotide fomivirsen (ISIS 2922)

1 reference

12 December 2020

Resveratrol induces DNA double-strand breaks through human topoisomerase II interaction

1 reference

12 December 2020

Dietary flavonoids and the MLL gene: A pathway to infant leukemia?

1 reference

12 December 2020

Isolation of human monoclonal antibodies that potently neutralize human cytomegalovirus infection by targeting different epitopes on the gH/gL/UL128-131A complex

1 reference

12 December 2020

Specificities of heparan sulphate proteoglycans in developmental processes

1 reference

12 December 2020

Historical overview of the use of cytomegalovirus hyperimmune globulin in organ transplantation.

1 reference

12 December 2020

Aciclovir. A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic efficacy

1 reference

12 December 2020

NF-kappaB-mediated activation of the chemokine CCL22 by the product of the human cytomegalovirus gene UL144 escapes regulation by viral IE86.

1 reference

12 December 2020

Sulfated K5 Escherichia coli polysaccharide derivatives as wide-range inhibitors of genital types of human papillomavirus.

1 reference

12 December 2020

TAF-like functions of human cytomegalovirus immediate-early proteins

1 reference

12 December 2020

Antiviral activity of 5,6,7-trimethoxyflavone and its potentiation of the antiherpes activity of acyclovir

1 reference

12 December 2020

Dendritic-cell infection by human cytomegalovirus is restricted to strains carrying functional UL131-128 genes and mediates efficient viral antigen presentation to CD8+ T cells.

1 reference

12 December 2020

Binding of the human cytomegalovirus 80-kDa immediate-early protein (IE2) to minor groove A/T-rich sequences bounded by CG dinucleotides is regulated by protein oligomerization and phosphorylation

1 reference

12 December 2020

Lactoferrin: molecular structure and biological function

1 reference

12 December 2020

Proteasome inhibitor MG132 blocks viral DNA replication and assembly of human cytomegalovirus.

1 reference

12 December 2020

Human cytomegalovirus UL131 open reading frame is required for epithelial cell tropism

1 reference

12 December 2020

Acyclic nucleoside phosphonates: a key class of antiviral drugs

1 reference

12 December 2020

Polymer nanocarriers for the delivery of small fragments of nucleic acids: oligonucleotides and siRNA.

1 reference

12 December 2020

Evaluation of neutralizing antibody titers against human cytomegalovirus in intravenous gamma globulin preparations

1 reference

12 December 2020

The genus Scutellaria an ethnopharmacological and phytochemical review

1 reference

12 December 2020

Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas

1 reference

12 December 2020

Synergy of bovine lactoferrin with the anti-cytomegalovirus drug cidofovir in vitro

1 reference

12 December 2020

Management of CMV infection and disease in transplant patients. 27-29 February 2004.

1 reference

12 December 2020

Disposition and toxicity of a mixed backbone antisense oligonucleotide, targeted against human cytomegalovirus, after intravitreal injection of escalating single doses in the rabbit

1 reference

12 December 2020

Nuclear localization of tegument-delivered pp71 in human cytomegalovirus-infected cells is facilitated by one or more factors present in terminally differentiated fibroblasts

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12 December 2020

Lactoferrin and cyclic lactoferricin inhibit the entry of human cytomegalovirus into human fibroblasts

1 reference

12 December 2020

Epigenetic regulation of gene expression as an anticancer drug target

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12 December 2020

Antiviral drug resistance of human cytomegalovirus

1 reference

12 December 2020

More to "heparin" than anticoagulation

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12 December 2020

Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

1 reference

12 December 2020

Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments.

1 reference

12 December 2020

Mutation in the UL97 open reading frame of human cytomegalovirus strains resistant to ganciclovir.

1 reference

12 December 2020

Role of the cytomegalovirus major immediate early enhancer in acute infection and reactivation from latency

1 reference

12 December 2020

Effect of resveratrol on herpes simplex virus vaginal infection in the mouse

1 reference

12 December 2020

Functional properties of the human cytomegalovirus IE86 protein required for transcriptional regulation and virus replication

1 reference

12 December 2020

Antiviral activity of Arthrospira-derived spirulan-like substances

1 reference

12 December 2020

Human cytomegalovirus immediate early proteins and cell growth control

1 reference

12 December 2020

Functional interaction of the human cytomegalovirus IE2 protein with histone deacetylase 2 in infected human fibroblasts

1 reference

12 December 2020

Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes.

1 reference

12 December 2020

Enfuvirtide: from basic investigations to current clinical use.

1 reference

12 December 2020

1 reference

12 December 2020

Virucidal activity of a GT-rich oligonucleotide against herpes simplex virus mediated by glycoprotein B

1 reference

12 December 2020

Comparison of artemisinin suppositories with intravenous artesunate and intravenous quinine in the treatment of cerebral malaria

1 reference

12 December 2020

Biotechnological engineering of heparin/heparan sulphate: a novel area of multi-target drug discovery.

1 reference

12 December 2020

Generation of potent neutralizing human monoclonal antibodies against cytomegalovirus infection from immune B cells

1 reference

12 December 2020

Cytomegalovirus cell tropism, replication, and gene transfer in brain

1 reference

12 December 2020

Emergence of a ganciclovir-resistant human cytomegalovirus strain with a new UL97 mutation in an AIDS patient.

1 reference

12 December 2020

Mechanism of action of flavonoids as anti-inflammatory agents: a review

1 reference

12 December 2020

Identification of a small molecule that inhibits herpes simplex virus DNA Polymerase subunit interactions and viral replication

1 reference

12 December 2020

Tinkering with heparan sulfate sulfation to steer development

1 reference

12 December 2020

Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase

1 reference

12 December 2020

In vitro antiviral activities of Caesalpinia pulcherrima and its related flavonoids

1 reference

12 December 2020

UL74 of human cytomegalovirus contributes to virus release by promoting secondary envelopment of virions

1 reference

12 December 2020

Biological properties of baicalein in cardiovascular system

1 reference

12 December 2020

Human cytomegalovirus-inhibitory flavonoids: studies on antiviral activity and mechanism of action

1 reference

12 December 2020

Directed egress of animal viruses promotes cell-to-cell spread

1 reference

12 December 2020

Identification of a dendrimeric heparan sulfate-binding peptide that inhibits infectivity of genital types of human papillomaviruses.

1 reference

12 December 2020

New insights into the role of the subnuclear structure ND10 for viral infection

1 reference

12 December 2020

Isolation of an antiviral polysaccharide, nostoflan, from a terrestrial cyanobacterium, Nostoc flagelliforme

1 reference

12 December 2020

Valaciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in herpesvirus infections

1 reference

12 December 2020

Role of regulatory elements and the MAPK/ERK or p38 MAPK pathways for activation of human cytomegalovirus gene expression

1 reference

12 December 2020

An antivirally active sulfated polysaccharide from Sargassum horneri (TURNER) C. AGARDH.

1 reference

12 December 2020

Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2.

1 reference

12 December 2020

An immunostimulatory oligodeoxynucleotide containing a cytidine-guanosine motif protects senescence-accelerated mice from lethal influenza virus by augmenting the T helper type 1 response

1 reference

12 December 2020

An improved synthesis of resveratrol

1 reference

12 December 2020

Synergistic effect of flavones and flavonols against herpes simplex virus type 1 in cell culture. Comparison with the antiviral activity of propolis

1 reference

12 December 2020

Human cytomegalovirus UL131-128 genes are indispensable for virus growth in endothelial cells and virus transfer to leukocytes

1 reference

12 December 2020

The 6-aminoquinolone WC5 inhibits human cytomegalovirus replication at an early stage by interfering with the transactivating activity of viral immediate-early 2 protein

1 reference

12 December 2020

Cellular integrins function as entry receptors for human cytomegalovirus via a highly conserved disintegrin-like domain

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12 December 2020

Sulfated polysaccharides extracted from sea algae as potential antiviral drugs

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12 December 2020

Viral load in breast milk correlates with transmission of human cytomegalovirus to preterm neonates, but lactoferrin concentrations do not

1 reference

12 December 2020

Galactan sulfate of Grateloupia indica: Isolation, structural features and antiviral activity

1 reference

12 December 2020

Structure and antiviral activity of sulfated fucans from Stoechospermum marginatum.

1 reference

12 December 2020

Microtubule network facilitates nuclear targeting of human cytomegalovirus capsid

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12 December 2020

Novel sulfated polysaccharides: dissociation of anti-human immunodeficiency virus activity from antithrombin activity.

1 reference

12 December 2020

Phosphorothioate-modified oligodeoxynucleotides inhibit human cytomegalovirus replication by blocking virus entry.

1 reference

12 December 2020

The phosphorylation status of the serine-rich region of the human cytomegalovirus 86-kilodalton major immediate-early protein IE2/IEP86 affects temporal viral gene expression

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12 December 2020

Proteasome inhibitors: a novel tool to suppress human cytomegalovirus replication and virus-induced immune modulation.

1 reference

12 December 2020

A 6-aminoquinolone compound, WC5, with potent and selective anti-human cytomegalovirus activity

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12 December 2020

Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropism

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12 December 2020

The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus.

1 reference

12 December 2020

Selective inhibition of platelet lipoxygenase by baicalein

1 reference

12 December 2020

Sulfated K5 Escherichia coli polysaccharide derivatives: A novel class of candidate antiviral microbicides

1 reference

12 December 2020

Antiviral activities against HSV-1, HCMV, and HIV-1 of rhamnan sulfate from Monostroma latissimum

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12 December 2020

Albumin nanoparticles for the intravitreal delivery of anticytomegaloviral drugs

1 reference

12 December 2020

Role of the proximal enhancer of the major immediate-early promoter in human cytomegalovirus replication

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12 December 2020

Coding potential of laboratory and clinical strains of human cytomegalovirus

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12 December 2020

Lactoferrin inhibits herpes simplex virus type 1 adsorption to Vero cells

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12 December 2020

Requirement of multiple cis-acting elements in the human cytomegalovirus major immediate-early distal enhancer for viral gene expression and replication

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12 December 2020

Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replication

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12 December 2020

Comparative activity of selected antiviral compounds against clinical isolates of human cytomegalovirus

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12 December 2020

Genistein induces topoisomerase IIbeta- and proteasome-mediated DNA sequence rearrangements: Implications in infant leukemia

1 reference

12 December 2020

Immunoglobulin prophylaxis in hematological malignancies and hematopoietic stem cell transplantation

1 reference

12 December 2020

Foscarnet. A review of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with cytomegalovirus retinitis

1 reference

12 December 2020

Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus

1 reference

12 December 2020

Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections

1 reference

12 December 2020

The case for cytomegalovirus prophylaxis in solid organ transplantation

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12 December 2020

Protein-protein interactions as targets for antiviral chemotherapy

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12 December 2020

Human cytomegalovirus immediate-early 2 protein IE86 blocks virus-induced chemokine expression

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12 December 2020

Effects of baicalein and esculetin on transduction signals and growth factors expression in T-lymphoid leukemia cells

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12 December 2020

Heparan sulfate: decoding a dynamic multifunctional cell regulator

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12 December 2020

The autoregulatory and transactivating functions of the human cytomegalovirus IE86 protein use independent mechanisms for promoter binding

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12 December 2020

Human cytomegalovirus resistance to antiviral drugs

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12 December 2020

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12 December 2020

Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains.

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12 December 2020

3,4',5-Trihydroxy-trans-stilbene (resveratrol) inhibits human cytomegalovirus replication and virus-induced cellular signaling

1 reference

12 December 2020

In vitro generation of human cytomegalovirus pp65 antigenemia, viremia, and leukoDNAemia

1 reference

12 December 2020

Antipoliovirus flavonoids from Psiadia dentata

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12 December 2020

Recent developments in herpesvirus therapy

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12 December 2020

The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio

1 reference

12 December 2020

Functional roles of the human cytomegalovirus essential IE86 protein

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12 December 2020

Peptide-derivatized dendrimers inhibit human cytomegalovirus infection by blocking virus binding to cell surface heparan sulfate.

1 reference

12 December 2020

Lactoferrin-mediated protection of the host from murine cytomegalovirus infection by a T-cell-dependent augmentation of natural killer cell activity

1 reference

12 December 2020

Molecular diversity of heparan sulfate

1 reference

12 December 2020

The human cytomegalovirus.

1 reference

12 December 2020

Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein.

1 reference

12 December 2020

Curdlan sulfate (CRDS) in a 21-day intravenous tolerance study in human immunodeficiency virus (HIV) and cytomegalovirus (CMV) infected patients: indication of anti-CMV activity with low toxicity.

1 reference

12 December 2020

Broad spectrum inhibition of HIV-1 infection by sulfated K5 Escherichia coli polysaccharide derivatives

1 reference

12 December 2020

Avoidance of bioflavonoid supplements during pregnancy: a pathway to infant leukemia?

1 reference

12 December 2020

Resveratrol inhibition of varicella-zoster virus replication in vitro

1 reference

12 December 2020

A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells

1 reference

12 December 2020

Inhibition of human cytomegalovirus DNA polymerase by C-terminal peptides from the UL54 subunit

1 reference

12 December 2020

Antiviral activity of berberine and related compounds against human cytomegalovirus

1 reference

12 December 2020

Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expression

1 reference

12 December 2020

Human cytomegalovirus UL47 tegument protein functions after entry and before immediate-early gene expression

1 reference

12 December 2020

Polysaccharides from Gracilaria corticata: sulfation, chemical characterization and anti-HSV activities

1 reference

12 December 2020

Inhibition of influenza A virus replication by resveratrol

1 reference

12 December 2020

Antimicrobial activity of flavonoids

1 reference

12 December 2020

Regulation of human cytomegalovirus by retinoic acid.

1 reference

12 December 2020

1 reference

12 December 2020

Cytomegalovirus vaccines fail to induce epithelial entry neutralizing antibodies comparable to natural infection

1 reference

12 December 2020

Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus

1 reference

12 December 2020

Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility

1 reference

12 December 2020

Coiled-coil domains in glycoproteins B and H are involved in human cytomegalovirus membrane fusion

1 reference

12 December 2020

Inhibition of inducible nitric oxide synthase expression by baicalein in endotoxin/cytokine-stimulated microglia

1 reference

12 December 2020

Cytomegalovirus cell tropism.

1 reference

12 December 2020

Ganciclovir. An update of its therapeutic use in cytomegalovirus infection

1 reference

12 December 2020

Functions of human cytomegalovirus tegument proteins prior to immediate early gene expression

1 reference

12 December 2020

The glycoprotein B disintegrin-like domain binds beta 1 integrin to mediate cytomegalovirus entry

1 reference

12 December 2020

Intranuclear delivery of an antiviral peptide mediated by the B subunit of Escherichia coli heat-labile enterotoxin.

1 reference

12 December 2020

Mechanisms of cytomegalovirus-accelerated vascular disease: induction of paracrine factors that promote angiogenesis and wound healing

1 reference

12 December 2020

Plus- and minus-end directed microtubule motors bind simultaneously to herpes simplex virus capsids using different inner tegument structures

1 reference

12 December 2020

Herpesvirus capsid association with the nuclear pore complex and viral DNA release involve the nucleoporin CAN/Nup214 and the capsid protein pUL25.

1 reference

12 December 2020

Human cytomegalovirus immediate-early 1 protein facilitates viral replication by antagonizing histone deacetylation

1 reference

12 December 2020

The human cytomegalovirus 86-kilodalton major immediate-early protein interacts physically and functionally with histone acetyltransferase P/CAF.

1 reference

12 December 2020

Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection

1 reference

12 December 2020

Disruption of the interactions between the subunits of herpesvirus DNA polymerases as a novel antiviral strategy

1 reference

12 December 2020

Role of the human cytomegalovirus major immediate-early promoter's 19-base-pair-repeat cyclic AMP-response element in acutely infected cells

1 reference

12 December 2020

Human cytomegalovirus penetrates host cells by pH-independent fusion at the cell surface

1 reference

12 December 2020

Transcriptional activation by the human cytomegalovirus immediate-early proteins: requirements for simple promoter structures and interactions with multiple components of the transcription complex.

1 reference

12 December 2020

Expression of human cytomegalovirus UL36 and UL37 genes is required for viral DNA replication

1 reference

12 December 2020

Valganciclovir: a review of its use in the management of CMV infection and disease in immunocompromised patients

1 reference

12 December 2020

Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group.

1 reference

12 December 2020

Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir

1 reference

12 December 2020

The human cytomegalovirus UL74 gene encodes the third component of the glycoprotein H-glycoprotein L-containing envelope complex

1 reference

12 December 2020

Establishment of a cell-based assay for screening of compounds inhibiting very early events in the cytomegalovirus replication cycle and characterization of a compound identified using the assay

1 reference

12 December 2020

10.1016/J.PHARMTHERA.2011.04.007

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21570424