Molecular mechanisms underlying the regulation and functional plasticity of FOXP3(+) regulatory T cells (Q37952092)

25 August 2017

title

Molecular mechanisms underlying the regulation and functional plasticity of FOXP3(+) regulatory T cells (English)

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25 August 2017

Y Gao

1

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25 August 2017

F Lin

2

1 reference

25 August 2017

J Su

3

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25 August 2017

Z Gao

4

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25 August 2017

Y Li

5

1 reference

25 August 2017

J Yang

6

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25 August 2017

Z Deng

7

1 reference

25 August 2017

B Liu

8

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25 August 2017

A Tsun

9

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25 August 2017

B Li

10

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25 August 2017

publication date

3 November 2011

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25 August 2017

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25 August 2017

volume

13

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25 August 2017

issue

1

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25 August 2017

page(s)

1-13

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https://scigraph.springernature.com/pub.10.1038/gene.2011.77

25 August 2017

exact match

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cites work

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Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth

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Multipotent mesenchymal stromal cells express FoxP3: a marker for the immunosuppressive capacity?

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Phenotypical and functional specialization of FOXP3+ regulatory T cells

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TGF-beta 1 differentially regulates IL-2 expression and [3H]-thymidine incorporation in CD3 epsilon mAb- and CD28 mAb-activated splenocytes and thymocytes

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Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors.

21 January 2018

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

21 January 2018

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https://api.crossref.org/works/10.1038%2FGENE.2011.77

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Transforming growth factor-beta induces development of the T(H)17 lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

21 January 2018

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https://api.crossref.org/works/10.1038%2FGENE.2011.77

Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases

21 January 2018

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https://api.crossref.org/works/10.1038%2FGENE.2011.77

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

21 January 2018

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https://api.crossref.org/works/10.1038%2FGENE.2011.77

The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.

21 January 2018

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https://api.crossref.org/works/10.1038%2FGENE.2011.77

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Transient regulatory T-cells: a state attained by all activated human T-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Stability of the regulatory T cell lineage in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Functional plasticity of antigen-specific regulatory T cells in context of tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

IL-17- and IFN-γ-secreting Foxp3+ T cells infiltrate the target tissue in experimental autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

IL-1beta and IL-2 convert human Treg into T(H)17 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Identification of T helper type 1-like, Foxp3+ regulatory T cells in human autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

An intrinsic mechanism predisposes Foxp3-expressing regulatory T cells to Th2 conversion in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

IL-1β-mediated signals preferentially drive conversion of regulatory T cells but not conventional T cells into IL-17-producing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Cutting edge: Foxp3+CD4+CD25+ regulatory T cells induced by IL-2 and TGF-beta are resistant to Th17 conversion by IL-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Characterization of protective human CD4CD25 FOXP3 regulatory T cells generated with IL-2, TGF-β and retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Cutting edge: all-trans retinoic acid sustains the stability and function of natural regulatory T cells in an inflammatory milieu.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Foxp3+ follicular regulatory T cells control the germinal center response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Interleukin-12 converts Foxp3+ regulatory T cells to interferon-γ-producing Foxp3+ T cells that inhibit colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Molecular mechanisms underlying FOXP3 induction in human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Epigenetic control of the foxp3 locus in regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

T regulatory cells in cord blood--FOXP3 demethylation as reliable quantitative marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

FOXP3 promoter demethylation reveals the committed Treg population in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

DNA methylation controls Foxp3 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

The Ets-1 transcription factor controls the development and function of natural regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

The ligase PIAS1 restricts natural regulatory T cell differentiation by epigenetic repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Foxo transcription factors control regulatory T cell development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Noncanonical K27-linked polyubiquitination of TIEG1 regulates Foxp3 expression and tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

STAT6 Inhibits TGF-beta1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

An essential role of the transcription factor GATA-3 for the function of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

JunB and c-Rel cooperatively enhance Foxp3 expression during induced regulatory T cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

CD28 costimulation regulates FOXP3 in a RelA/NF-κB-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Regulatory T cells and immune tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

IL-2 controls the stability of Foxp3 expression in TGF-beta-induced Foxp3+ T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Nonredundant roles for Stat5a/b in directly regulating Foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

RORC2 is involved in T cell polarization through interaction with the FOXP3 promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Notch3 and canonical NF-kappaB signaling pathways cooperatively regulate Foxp3 transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

An extensive class of small RNAs in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Identification of novel genes coding for small expressed RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

MicroRNAs: target recognition and regulatory functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Mammalian microRNAs predominantly act to decrease target mRNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

MicroRNAs modulate hematopoietic lineage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Small RNAs guide hematopoietic cell differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

MicroRNAs: the fine-tuners of Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Physiological and pathological roles for microRNAs in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

MicroRNA control of lymphocyte differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

A role for Dicer in immune regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Aberrant T cell differentiation in the absence of Dicer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Dicer-dependent microRNA pathway safeguards regulatory T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 in FOXP3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Valproate treatment of human cord blood CD4-positive effector T cells confers on them the molecular profile (microRNA signature and FOXP3 expression) of natural regulatory CD4-positive cells through inhibition of histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Requirement of bic/microRNA-155 for normal immune function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Regulation of the germinal center response by microRNA-155

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

miR-155, a Modulator of FOXO3a Protein Expression, Is Underexpressed and Cannot Be Upregulated by Stimulation of HOZOT, a Line of Multifunctional Treg

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

miR-142-3p restricts cAMP production in CD4+CD25- T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Inhibition of cAMP degradation improves regulatory T cell-mediated suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Altered miRNA expression in T regulatory cells in course of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Dicer insufficiency and microRNA-155 overexpression in lupus regulatory T cells: an apparent paradox in the setting of an inflammatory milieu

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Regulation of microRNA expression and abundance during lymphopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

FOXP3 and its partners: structural and biochemical insights into the regulation of FOXP3 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Foxp3 processing by proprotein convertases and control of regulatory T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Three distinct domains contribute to nuclear transport of murine Foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Partners in transcription: NFAT and AP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Transcription factors of the NFAT family: regulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

FOXP3 controls regulatory T cell function through cooperation with NFAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Regulation of gene expression in peripheral T cells by Runx transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Foxp3 interacts with c-Rel to mediate NF-κB repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Acetylation is indispensable for p53 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Acetylation of the p53 DNA-binding domain regulates apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Direct activation of protein kinases by unanchored polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Post-translational modification of p53 in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Deacetylase inhibition promotes the generation and function of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Rapid temporal control of Foxp3 protein degradation by sirtuin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

Identification of Regulatory Foxp3+ Invariant NKT Cells Induced by TGF-

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

7 January 2021

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

7 January 2021

Myelin-reactive, TGF-β-induced regulatory T cells can be programmed to develop Th1-like effector function but remain less proinflammatory than myelin-reactive Th1 effectors and can suppress pathogenic T cell clonal expansion in vivo

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

7 January 2021

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

7 January 2021

Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

7 January 2021

CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

7 January 2021

Notch signaling regulates the FOXP3 promoter through RBP-J- and Hes1-dependent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

7 January 2021

microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2011.77

7 January 2021

Identifiers

DOI

10.1038/GENE.2011.77

1 reference

Dimensions Publication ID

25 August 2017

1022703037

0 references

1 reference