T-cell acute lymphoblastic leukaemia: recent molecular biology findings (Q37965247)

26 August 2017

T-cell acute lymphoblastic leukaemia: recent molecular biology findings (English)

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26 August 2017

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1

Monika D Kraszewska

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26 August 2017

3

Tomasz Szczepański

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26 August 2017

4

Michał Witt

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PubMed ID

22145858

26 August 2017

Małgorzata Dawidowska

series ordinal

2

object named as

Małgorzata Dawidowska

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PubMed ID

22145858

26 August 2017

language of work or name

English

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publication date

7 December 2011

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British Journal of Haematology

26 August 2017

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26 August 2017

156

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26 August 2017

3

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26 August 2017

303-315

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NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study

26 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

HOX11L2 expression defines a clinical subtype of pediatric T-ALL associated with poor prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Rearranged T-cell receptor beta genes represent powerful targets for quantification of minimal residual disease in childhood and adult T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Standardized MRD quantification in European ALL trials: proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Paediatric lymphoblastic T-cell leukaemia and lymphoma: one or two diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Chromosomal translocation involving the beta T cell receptor gene in acute leukemia

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Implementation of the standard strategy for identification of Ig/TCR targets for minimal residual disease diagnostics in B-cell precursor ALL pediatric patients: Polish experience

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

The TLX1 oncogene drives aneuploidy in T cell transformation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

21 January 2018

It's T-ALL about Notch

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leu

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Association of JC virus T-antigen expression with the methylator phenotype in sporadic colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Gene expression profiles in BCL11B-siRNA treated malignant T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Bcl11b represses a mature T-cell gene expression program in immature CD4(+)CD8(+) thymocytes

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

A transforming gene present in human sarcoma cell lines

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Genetic rearrangements in relation to immunophenotype and outcome in T-cell acute lymphoblastic leukaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

LYL1 activity is required for the maturation of newly formed blood vessels in adulthood

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Poor prognosis in acute lymphoblastic leukemia may relate to promoter hypermethylation of cancer-related genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Regulating antigen-receptor gene assembly

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

HOX gene expression in phenotypic and genotypic subgroups and low HOXA gene expression as an adverse prognostic factor in pediatric ALL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Genetic aberrations in paediatric acute leukaemias and implications for management of patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

21 January 2018

WT1 mutations in T-ALL

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

CpG island methylator phenotype in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

PHF6 mutations in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Detection of minimal residual disease identifies differences in treatment response between T-ALL and precursor B-ALL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Therapeutic antibody targeting of individual Notch receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Mutational analysis of the N-ras gene in acute lymphoblastic leukemia: a study of 125 Japanese pediatric cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

Acute lymphoblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

T-cell lymphoblastic leukemia in early childhood presents NOTCH1 mutations and MLL rearrangements

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2011.08957.X

10.1111/J.1365-2141.2011.08957.X

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22145858