Regulation of gene expression in atherosclerosis: insights from microarray studies in monocytes/macrophages (Q37989491)

26 August 2017

title

Regulation of gene expression in atherosclerosis: insights from microarray studies in monocytes/macrophages (English)

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26 August 2017

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Marta Alegret

2

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Juan C. Laguna

object named as

Juan C Laguna

series ordinal

1

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publication date

1 March 2012

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26 August 2017

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26 August 2017

volume

13

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26 August 2017

issue

4

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26 August 2017

page(s)

477-495

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Toll-like receptors and macrophage activation in atherosclerosis

26 August 2017

cites work

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Genetics, genomics and proteomics in atherosclerosis research

21 January 2018

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Progress and challenges in translating the biology of atherosclerosis

21 January 2018

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Macrophages in the pathogenesis of atherosclerosis

21 January 2018

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Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.

21 January 2018

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P-selectin glycoprotein ligand-1 plays a crucial role in the selective recruitment of leukocytes into the atherosclerotic arterial wall.

21 January 2018

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Macrophage heterogeneity in atherosclerotic plaques

21 January 2018

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Inflammation, atherosclerosis, and coronary artery disease

21 January 2018

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Monocyte and macrophage heterogeneity

21 January 2018

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Macrophage activation and polarization

21 January 2018

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Macrophage diversity and polarization in atherosclerosis: a question of balance

21 January 2018

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Thematic review series: The immune system and atherogenesis. Paying the price for pathogen protection: toll receptors in atherogenesis

21 January 2018

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Scavenger receptors in atherosclerosis: beyond lipid uptake

21 January 2018

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Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

21 January 2018

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Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice

21 January 2018

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Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

21 January 2018

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Absence of CD36 protects against atherosclerosis in ApoE knock-out mice with no additional protection provided by absence of scavenger receptor A I/II

21 January 2018

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Sequestration of aggregated low-density lipoproteins by macrophages

21 January 2018

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Macropinocytosis is the endocytic pathway that mediates macrophage foam cell formation with native low density lipoprotein

21 January 2018

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Toll-like receptor-4 and lipoprotein accumulation in macrophages

21 January 2018

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Toll-like receptor 4 mediates oxidized LDL-induced macrophage differentiation to foam cells.

21 January 2018

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Mammalian acyl-CoA:cholesterol acyltransferases

21 January 2018

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High-density lipoprotein heterogeneity and function in reverse cholesterol transport

21 January 2018

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HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis

21 January 2018

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Adipophilin increases triglyceride storage in human macrophages by stimulation of biosynthesis and inhibition of beta-oxidation

21 January 2018

1 reference

How dendritic cells shape atherosclerosis

21 January 2018

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Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

21 January 2018

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Modulation of atherosclerosis in mice by Toll-like receptor 2

21 January 2018

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Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis

21 January 2018

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CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

21 January 2018

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Interleukins in atherosclerosis: molecular pathways and therapeutic potential

21 January 2018

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Immunological and inflammatory functions of the interleukin-1 family

21 January 2018

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Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

21 January 2018

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The membrane form of the type II IL-1 receptor accounts for inhibitory function

21 January 2018

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Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

21 January 2018

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

21 January 2018

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21 January 2018

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Changing concepts of atherogenesis

21 January 2018

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Is thrombin a key player in the 'coagulation-atherogenesis' maze?

21 January 2018

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Intertwining of thrombosis and inflammation in atherosclerosis

21 January 2018

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Mechanisms of plaque vulnerability and rupture

21 January 2018

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Genomewide association studies and assessment of the risk of disease

21 January 2018

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Genome-wide association studies in atherosclerosis

21 January 2018

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Biological, clinical and population relevance of 95 loci for blood lipids

21 January 2018

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Quantitative monitoring of gene expression patterns with a complementary DNA microarray

21 January 2018

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Integrating global gene expression analysis and genetics

21 January 2018

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Analysis of large-scale gene expression data

21 January 2018

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Techniques for clustering gene expression data

21 January 2018

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Bioinformatics applications for pathway analysis of microarray data

21 January 2018

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A statistical framework for differential network analysis from microarray data

21 January 2018

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The use of network analyses for elucidating mechanisms in cardiovascular disease

21 January 2018

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Content-based microarray search using differential expression profiles

21 January 2018

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RNA-Seq: a revolutionary tool for transcriptomics

21 January 2018

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Microarrays, deep sequencing and the true measure of the transcriptome

21 January 2018

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Genome-wide location and function of DNA binding proteins

21 January 2018

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Chromatin immunoprecipitation and microarray-based analysis of protein location

21 January 2018

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ChIP-Seq using high-throughput DNA sequencing for genome-wide identification of transcription factor binding sites

21 January 2018

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Reliability and reproducibility of gene expression measurements using amplified RNA from laser-microdissected primary breast tissue with oligonucleotide arrays

21 January 2018

1 reference

Oxidized low-density lipoprotein correlates positively with toll-like receptor 2 and interferon regulatory factor-1 and inversely with superoxide dismutase-1 expression: studies in hypercholesterolemic swine and THP-1 cells

21 January 2018

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Maternal hypercholesterolemia during pregnancy promotes early atherogenesis in LDL receptor-deficient mice and alters aortic gene expression determined by microarray

21 January 2018

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Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease

21 January 2018

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Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease.

21 January 2018

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Molecular evidence for arterial repair in atherosclerosis

21 January 2018

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Microarray gene profiling of laser-captured cells: a new tool to study atherosclerosis in mice

21 January 2018

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Laser-capture microdissection of hyperlipidemic/ApoE⁻/⁻ mouse aorta atherosclerosis

21 January 2018

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Mouse models for atherosclerosis and pharmaceutical modifiers.

21 January 2018

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Understanding hyperlipidemia and atherosclerosis: lessons from genetically modified apoe and ldlr mice

21 January 2018

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Atherosclerotic lesions in mouse and man: is it the same disease?

21 January 2018

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Frontiers in nephrology: genomic approaches to understanding the molecular basis of atherosclerosis

21 January 2018

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Network analysis of human in-stent restenosis

21 January 2018

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Expression profiling identifies smooth muscle cell diversity within human intima and plaque fibrous cap: loss of RGS5 distinguishes the cap

21 January 2018

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Dead or alive: gene expression profiles of advanced atherosclerotic plaques from autopsy and surgery.

21 January 2018

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Equivalence testing in microarray analysis: similarities in the transcriptome of human atherosclerotic and nonatherosclerotic macrophages.

21 January 2018

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Reconstruction and functional analysis of altered molecular pathways in human atherosclerotic arteries

21 January 2018

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Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow

21 January 2018

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Gene expression profiling of vascular endothelial cells exposed to fluid mechanical forces: relevance for focal susceptibility to atherosclerosis

21 January 2018

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Chlamydia pneumoniae (C. pneumoniae) infection upregulates atherosclerosis-related gene expression in human umbilical vein endothelial cells (HUVECs).

21 January 2018

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NF-kappaB controls the global pro-inflammatory response in endothelial cells: evidence for the regulation of a pro-atherogenic program

21 January 2018

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Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids

21 January 2018

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Up-regulation of cell adhesion molecule genes in human endothelial cells stimulated by lymphotoxin alpha: DNA microarray analysis.

21 January 2018

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Gene expression in endothelial cells and intimal smooth muscle cells in atherosclerosis-prone or atherosclerosis-resistant regions of the human aorta.

21 January 2018

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In vivo differences between endothelial transcriptional profiles of coronary and iliac arteries revealed by microarray analysis

21 January 2018

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Cholesterol regulation of genes involved in sterol trafficking in human THP-1 macrophages

21 January 2018

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Reduction of intracellular cholesterol accumulation in THP-1 macrophages by a combination of rosiglitazone and atorvastatin

21 January 2018

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Atorvastatin reduces CD68, FABP4, and HBP expression in oxLDL-treated human macrophages

21 January 2018

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Small dense LDL enhances THP-1 macrophage foam cell formation

21 January 2018

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A comparison of differences in the gene expression profiles of phorbol 12-myristate 13-acetate differentiated THP-1 cells and human monocyte-derived macrophage

21 January 2018

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Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

21 January 2018

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Transcriptional diversity during monocyte to macrophage differentiation

21 January 2018

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Interleukin-1beta and tumour necrosis factor-alpha impede neutral lipid turnover in macrophage-derived foam cells

21 January 2018

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Large scale gene expression analysis of cholesterol-loaded macrophages

21 January 2018

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Oxidized low density lipoprotein exposure alters the transcriptional response of macrophages to inflammatory stimulus

21 January 2018

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Inhibition of foam cell formation using a soluble CD68-Fc fusion protein.

21 January 2018

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The adipocyte lipid binding protein (ALBP/aP2) gene facilitates foam cell formation in human THP-1 macrophages

21 January 2018

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Effects of oxidized low- and high-density lipoproteins on gene expression of human macrophages

21 January 2018

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Decreased Macrophage Paraoxonase 2 Expression in Patients With Hypercholesterolemia Is the Result of Their Increased Cellular Cholesterol Content: Effect of Atorvastatin Therapy

21 January 2018

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Cholesterol loading augments oxidative stress in macrophages

21 January 2018

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Oxidized LDL induces a coordinated up-regulation of the glutathione and thioredoxin systems in human macrophages

21 January 2018

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N-acetyl cysteine suppresses the foam cell formation that is induced by oxidized low density lipoprotein via regulation of gene expression

21 January 2018

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MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages

21 January 2018

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Different responses to oxidized low-density lipoproteins in human polarized macrophages

21 January 2018

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Increased expression of the DNA-binding cytokine HMGB1 in human atherosclerotic lesions: role of activated macrophages and cytokines.

21 January 2018

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Transforming growth factor-beta1 inhibits macrophage cholesteryl ester accumulation induced by native and oxidized VLDL remnants

21 January 2018

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Peripheral blood gene expression profiling for cardiovascular disease assessment

21 January 2018

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Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects

21 January 2018

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Differential gene expression of blood-derived cell lines in familial combined hyperlipidemia

21 January 2018

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High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis.

21 January 2018

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Early growth response-1 promotes atherogenesis: mice deficient in early growth response-1 and apolipoprotein E display decreased atherosclerosis and vascular inflammation

21 January 2018

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Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism

21 January 2018

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Atorvastatin affects leukocyte gene expression in dyslipidemia patients: in vivo regulation of hemostasis, inflammation and apoptosis

21 January 2018

1 reference

Monocyte gene-expression profile in men with familial combined hyperlipidemia and its modification by atorvastatin treatment

21 January 2018

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Type II interleukin-1 receptor expression is reduced in monocytes/macrophages and atherosclerotic lesions

21 January 2018

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Tissue factor pathway inhibitor 2 is induced by thrombin in human macrophages

21 January 2018

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Expression and localization of tissue factor pathway inhibitor-2 in normal and atherosclerotic human vessels

21 January 2018

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Recombinant TFPI-2 enhances macrophage apoptosis through upregulation of Fas/FasL.

21 January 2018

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A gene expression signature that classifies human atherosclerotic plaque by relative inflammation status.

21 January 2018

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Genetics and beyond--the transcriptome of human monocytes and disease susceptibility

21 January 2018

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Microarray analysis of gene expression in mouse aorta reveals role of the calcium signaling pathway in control of atherosclerosis susceptibility

21 January 2018

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Transcriptional profiling uncovers a network of cholesterol-responsive atherosclerosis target genes

21 January 2018

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Predominance of a proinflammatory phenotype in monocyte-derived macrophages from subjects with low plasma HDL-cholesterol

21 January 2018

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CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages

21 January 2018

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Oxidized LDL immune complexes and oxidized LDL differentially affect the expression of genes involved with inflammation and survival in human U937 monocytic cells

21 January 2018

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Increased expression of interleukin-1 in coronary artery disease with downregulatory effects of HMG-CoA reductase inhibitors

21 January 2018

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Gene expression patterns in peripheral blood correlate with the extent of coronary artery disease

21 January 2018

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PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/PGS.12.9

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release_4qzsna47rjevpnsbcorxxdhqam

26 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/4qzsna47rjevpnsbcorxxdhqam

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24 November 2022

based on heuristic

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