Integrating novel signaling pathways involved in erythropoiesis (Q37995112)

26 August 2017

Integrating novel signaling pathways involved in erythropoiesis (English)

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26 August 2017

Evan Ingley

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publication date

20 March 2012

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26 August 2017

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26 August 2017

64

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26 August 2017

5

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26 August 2017

402-410

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A unifying concept: the history of cell theory

26 August 2017

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New insights into the regulation of erythroid cells.

21 January 2018

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Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1

21 January 2018

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Involvement of phosphatases in proliferation, maturation, and hemoglobinization of developing erythroid cells

21 January 2018

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From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications

21 January 2018

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The erythropoietin receptor: molecular structure and hematopoietic signaling pathways

21 January 2018

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Erythropoiesis: model systems, molecular regulators, and developmental programs

21 January 2018

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Homodimerization and constitutive activation of the erythropoietin receptor

21 January 2018

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Activation and inhibition of erythropoietin receptor function: role of receptor dimerization

21 January 2018

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Inhibition of Smad5 in human hematopoietic progenitors blocks erythroid differentiation induced by BMP4.

21 January 2018

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BMP4, SCF, and hypoxia cooperatively regulate the expansion of murine stress erythroid progenitors

21 January 2018

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Maintenance of the BMP4-dependent stress erythropoiesis pathway in the murine spleen requires hedgehog signaling

21 January 2018

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Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture system

21 January 2018

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Molecular biology of erythropoietin

21 January 2018

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HIF1alpha synergizes with glucocorticoids to promote BFU-E progenitor self-renewal

21 January 2018

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The glucocorticoid receptor is a key regulator of the decision between self-renewal and differentiation in erythroid progenitors

21 January 2018

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The thyroid hormone receptor functions as a ligand-operated developmental switch between proliferation and differentiation of erythroid progenitors.

21 January 2018

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Thyroid hormone T3 acting through the thyroid hormone alpha receptor is necessary for implementation of erythropoiesis in the neonatal spleen environment in the mouse

21 January 2018

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Erythroid defects in TRalpha-/- mice

21 January 2018

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Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts

21 January 2018

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Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression

21 January 2018

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Identification of the transferrin receptor as a novel immunoglobulin (Ig)A1 receptor and its enhanced expression on mesangial cells in IgA nephropathy

21 January 2018

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Identification of the human erythropoietin receptor region required for Stat1 and Stat3 activation

21 January 2018

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A novel role for STAT1 in regulating murine erythropoiesis: deletion of STAT1 results in overall reduction of erythroid progenitors and alters their distribution

21 January 2018

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Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells

21 January 2018

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Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

21 January 2018

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Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

21 January 2018

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JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

21 January 2018

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Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

21 January 2018

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Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation

21 January 2018

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Model for growth hormone receptor activation based on subunit rotation within a receptor dimer

21 January 2018

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Erythropoietin-dependent inhibition of apoptosis is supported by carboxyl-truncated receptor forms and blocked by dominant-negative forms of Jak2.

21 January 2018

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In vitro phosphorylation of the erythropoietin receptor and an associated protein, pp130

21 January 2018

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Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation.

21 January 2018

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AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation.

21 January 2018

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Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice

21 January 2018

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Erythropoietin receptor Y479 couples to ERK1/2 activation via recruitment of phospholipase Cgamma

21 January 2018

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Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells

21 January 2018

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Perturbed myelo/erythropoiesis in Lyn-deficient mice is similar to that in mice lacking the inhibitory phosphatases SHP-1 and SHIP-1.

21 January 2018

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Lyn deficiency reduces GATA-1, EKLF and STAT5, and induces extramedullary stress erythropoiesis.

21 January 2018

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CrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signaling

21 January 2018

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Lyn kinase promotes erythroblast expansion and late-stage development

21 January 2018

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Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage

21 January 2018

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JAKs, STATs and Src kinases in hematopoiesis

21 January 2018

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Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity

21 January 2018

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Csk-binding protein mediates sequential enzymatic down-regulation and degradation of Lyn in erythropoietin-stimulated cells.

21 January 2018

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Csk-binding protein can regulate Lyn signals controlling cell morphology

21 January 2018

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Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation

21 January 2018

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Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

21 January 2018

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Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

21 January 2018

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Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton

21 January 2018

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A novel negative regulatory function of the phosphoprotein associated with glycosphingolipid-enriched microdomains: blocking Ras activation

21 January 2018

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Src family kinases: regulation of their activities, levels and identification of new pathways

21 January 2018

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A family of cytokine-inducible inhibitors of signalling

21 January 2018

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Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.

21 January 2018

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Differential regulation of SOCS genes in normal and transformed erythroid cells

21 January 2018

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Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

21 January 2018

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A critical role for SHP2 in STAT5 activation and growth factor-mediated proliferation, survival, and differentiation of human CD34+ cells

21 January 2018

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TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

21 January 2018

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Protein tyrosine phosphatase 1B attenuates growth hormone-mediated JAK2-STAT signaling

21 January 2018

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CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2

21 January 2018

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Differential roles of SOCS family members in EpoR signal transduction

21 January 2018

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A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

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Ubiquitination regulates the internalization, endolysosomal sorting, and signaling of the erythropoietin receptor

21 January 2018

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The SH2 inositol 5-phosphatase Ship1 is recruited in an SH2-dependent manner to the erythropoietin receptor

21 January 2018

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Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

21 January 2018

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FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation

21 January 2018

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Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

21 January 2018

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Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

21 January 2018

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Transcription factor erythroid Krüppel-like factor (EKLF) is essential for the erythropoietin-induced hemoglobin production but not for proliferation, viability, or morphological maturation

21 January 2018

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Erythroid Kruppel-like factor (EKLF) coordinates erythroid cell proliferation and hemoglobinization in cell lines derived from EKLF null mice

21 January 2018

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The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

21 January 2018

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Regulation of Socs gene expression by the proto-oncoprotein GFI-1B: two routes for STAT5 target gene induction by erythropoietin

21 January 2018

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Transcriptional regulation of erythropoiesis: an affair involving multiple partners

21 January 2018

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Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway

21 January 2018

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GATA-1 transactivates erythropoietin receptor gene, and erythropoietin receptor-mediated signals enhance GATA-1 gene expression

21 January 2018

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Graded levels of GATA-1 expression modulate survival, proliferation, and differentiation of erythroid progenitors

21 January 2018

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Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage

21 January 2018

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Cooperation of Spi-1/PU.1 with an activated erythropoietin receptor inhibits apoptosis and Epo-dependent differentiation in primary erythroblasts and induces their Kit ligand-dependent proliferation

21 January 2018

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Differential context-dependent effects of friend of GATA-1 (FOG-1) on mast-cell development and differentiation

21 January 2018

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A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1.

21 January 2018

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FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors

21 January 2018

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Regulation of erythroid Krüppel-like factor (EKLF) transcriptional activity by phosphorylation of a protein kinase casein kinase II site within its interaction domain.

21 January 2018

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Controlling hematopoiesis through sumoylation-dependent regulation of a GATA factor

21 January 2018

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Sumoylation regulates interaction of FOG1 with C-terminal-binding protein (CTBP)

21 January 2018

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miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1.

21 January 2018

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A GATA-1-regulated microRNA locus essential for erythropoiesis

21 January 2018

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miR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta

21 January 2018

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Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation

21 January 2018

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Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia

21 January 2018

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An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IUB.1024

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26 August 2017

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PubMed ID

22431075