Therapeutic potential of the chemokine-receptor duo fractalkine/CX3CR1: an update (Q38005186)

26 August 2017

Therapeutic potential of the chemokine-receptor duo fractalkine/CX3CR1: an update (English)

1 reference

26 August 2017

2

Helmut Friess

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26 August 2017

3

Güralp O Ceyhan

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26 August 2017

Jan G D'Haese

1

1 reference

PubMed ID

22530606

26 August 2017

language of work or name

English

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publication date

25 April 2012

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Expert Opinion on Therapeutic Targets

26 August 2017

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26 August 2017

16

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26 August 2017

6

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26 August 2017

613-618

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A new class of membrane-bound chemokine with a CX3C motif

26 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Fractalkine/CX3CR1: why a single chemokine-receptor duo bears a major and unique therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Fractalkine reduces N-methyl-d-aspartate-induced calcium flux and apoptosis in human neurons through extracellular signal-regulated kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

CX(3)CR1 drives cytotoxic CD4(+)CD28(-) T cells into the brain of multiple sclerosis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Evidence that LPS-reactive arthritis in rats depends on the glial activity and the fractalkine-TNF-α signaling in the spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

The fractalkine receptor CX₃CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

High plasma fractalkine (CX3CL1) levels are associated with severe liver disease in HIV/HCV co-infected patients with HCV genotype 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Microglial/macrophage GRK2 determines duration of peripheral IL-1beta-induced hyperalgesia: contribution of spinal cord CX3CR1, p38 and IL-1 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Identification of the chemokine CX3CL1 as a new regulator of malignant cell proliferation in epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Fractalkine receptor CX(3)CR1 is expressed in epithelial ovarian carcinoma cells and required for motility and adhesion to peritoneal mesothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

CX3CR1/CX3CL1 axis negatively controls glioma cell invasion and is modulated by transforming growth factor-β1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Human glioblastoma tumours and neural cancer stem cells express the chemokine CX3CL1 and its receptor CX3CR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Regulation of tau pathology by the microglial fractalkine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Fractalkine/CX3CL1 depresses central synaptic transmission in mouse hippocampal slices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Fractalkine/CX3CL1 enhances GABA synaptic activity at serotonin neurons in the rat dorsal raphe nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Chemokine fractalkine/CX3CL1 negatively modulates active glutamatergic synapses in rat hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

CX3CL1 is neuroprotective in permanent focal cerebral ischemia in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

Spinal microglia initiate and maintain hyperalgesia in a rat model of chronic pancreatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

CX(3)CR1 deficiency alters hippocampal-dependent plasticity phenomena blunting the effects of enriched environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2012.682574

10.1517/14728222.2012.682574

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22530606