Chemistry and biology of the ubiquitin signal (Q38018581)

27 August 2017

title

Chemistry and biology of the ubiquitin signal (English)

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27 August 2017

Liat Spasser

1

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27 August 2017

Ashraf Brik

series ordinal

2

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27 August 2017

language of work or name

English

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publication date

13 June 2012

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Angewandte Chemie International Edition

27 August 2017

published in

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volume

51

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27 August 2017

issue

28

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27 August 2017

page(s)

6840-6862

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Protein posttranslational modifications: the chemistry of proteome diversifications

27 August 2017

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Activating the ubiquitin family: UBA6 challenges the field

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Polyubiquitin chains: polymeric protein signals

21 January 2018

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Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

21 January 2018

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A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis

21 January 2018

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A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles

21 January 2018

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Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation

21 January 2018

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Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase

21 January 2018

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Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201200020

Serine residues in the cytosolic tail of the T-cell antigen receptor alpha-chain mediate ubiquitination and endoplasmic reticulum-associated degradation of the unassembled protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201200020

Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitylation of an ERAD substrate occurs on multiple types of amino acids

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201200020

N-terminal ubiquitination: more protein substrates join in.

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201200020

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Nonproteolytic functions of ubiquitin in cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

The role of ubiquitin in NF-kappaB regulatory pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

K33-linked polyubiquitination of T cell receptor-zeta regulates proteolysis-independent T cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Constructing and decoding unconventional ubiquitin chains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Protein regulation by monoubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Distinct monoubiquitin signals in receptor endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Modification by single ubiquitin moieties rather than polyubiquitination is sufficient for proteasomal processing of the p105 NF-kappaB precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

The emerging complexity of protein ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Regulation of DNA repair by ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Expanding role of ubiquitination in NF-κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

PCNA, the maestro of the replication fork

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

TRAF7 protein promotes Lys-29-linked polyubiquitination of IkappaB kinase (IKKgamma)/NF-kappaB essential modulator (NEMO) and p65/RelA protein and represses NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Linear polyubiquitination: a new regulator of NF-kappaB activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Efficient internalization of MHC I requires lysine-11 and lysine-63 mixed linkage polyubiquitin chains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitin-binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitin-binding domains - from structures to functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitin-binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

A genomic and functional inventory of deubiquitinating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Chemistry-based functional proteomics: mechanism-based activity-profiling tools for ubiquitin and ubiquitin-like specific proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Mechanisms, biology and inhibitors of deubiquitinating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Strategies for the identification of novel inhibitors of deubiquitinating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Deubiquitinating enzymes as novel anticancer targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Polyubiquitin binding and disassembly by deubiquitinating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Breaking the chains: structure and function of the deubiquitinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Mechanism and function of deubiquitinating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Multiple faces of the SAGA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Insights into SAGA function during gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structural Insights into the Assembly and Function of the SAGA Deubiquitinating Module

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structural properties of polyubiquitin chains in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

The Structure and Conformation of Lys63-Linked Tetraubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Crystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structural Assembly of Multidomain Proteins and Protein Complexes Guided by the Overall Rotational Diffusion Tensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Various strategies of using residual dipolar couplings in NMR-driven protein docking: application to Lys48-linked di-ubiquitin and validation against 15N-relaxation data

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Conformational Dynamics of Wild-type Lys-48-linked Diubiquitin in Solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

A new crystal form of Lys48-linked diubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structure of tetraubiquitin shows how multiubiquitin chains can be formed

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structure of a new crystal form of tetraubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structure of a compact conformation of linear diubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Rad23 promotes the targeting of proteolytic substrates to the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Diverse polyubiquitin interaction properties of ubiquitin-associated domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structural determinants for selective recognition of a Lys48-linked polyubiquitin chain by a UBA domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Linkage-specific avidity defines the lysine 63-linked polyubiquitin-binding preference of rap80.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Inhibition of the 26 S proteasome by polyubiquitin chains synthesized to have defined lengths

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

The ubiquitination code: a signalling problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

In vitro assembly and recognition of Lys-63 polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Controlled synthesis of polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Controlled enzymatic synthesis of natural-linkage, defined-length polyubiquitin chains using lysines with removable protecting groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Accessing posttranslationally modified proteins through thiol positioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Chemoselective ligation and modification strategies for peptides and proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Synthesis of native proteins by chemical ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Synthetic, structural and biological studies of the ubiquitin system: the total chemical synthesis of ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Synthetic, structural and biological studies of the ubiquitin system: synthesis and crystal structure of an analogue containing unnatural amino acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Synthesis, structural and biological studies of ubiquitin mutants containing (2S, 4S)-5-fluoroleucine residues strategically placed in the hydrophobic core

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Total chemical synthesis and X-ray crystal structure of a protein diastereomer: [D-Gln 35]ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Synthesis of peptides and proteins without cysteine residues by native chemical ligation combined with desulfurization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

N-methylcysteine-mediated total chemical synthesis of ubiquitin thioester

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Expressed protein ligation: a general method for protein engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Biological applications of protein splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Semisynthesis of cytotoxic proteins using a modified protein splicing element

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitin C-terminal electrophiles are activity-based probes for identification and mechanistic study of ubiquitin conjugating machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Nonenzymatic ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Unraveling the complexity of ubiquitin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Auxiliary-mediated site-specific peptide ubiquitylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

A synthetic kiss of death: expressed protein ligation of a ubiquitin-peptide conjugate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Dual native chemical ligation at lysine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Free-radical-based, specific desulfurization of cysteine: a powerful advance in the synthesis of polypeptides and glycopolypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Highly efficient and chemoselective peptide ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Protecting group variations of delta-mercaptolysine useful in chemical ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Traceless and site-specific ubiquitination of recombinant proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Functional ubiquitin conjugates with lysine-epsilon-amino-specific linkage by thioether ligation of cysteinyl-ubiquitin peptide building blocks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

An efficient Fmoc-SPPS approach for the generation of thioester peptide precursors for use in native chemical ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structural basis for the specificity of ubiquitin C-terminal hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Substrate filtering by the active site crossover loop in UCHL3 revealed by sortagging and gain-of-function mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

The binding site for UCH-L3 on ubiquitin: mutagenesis and NMR studies on the complex between ubiquitin and UCH-L3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Identification of a novel 29-linked polyubiquitin binding protein, Ufd3, using polyubiquitin chain analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

A pyrrolysine analogue for site-specific protein ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Structure-activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubc9 sumoylation regulates SUMO target discrimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Synthesis of defined ubiquitin dimers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Total Chemical Synthesis of Di‐ubiquitin Chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Segmental isotopic labeling of ubiquitin chains to unravel monomer-specific molecular behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Nonenzymatic assembly of natural polyubiquitin chains of any linkage composition and isotopic labeling scheme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Synthesis of K48-linked diubiquitin using dual native chemical ligation at lysine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Recognition of the polyubiquitin proteolytic signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Chromatin Structure: A Repeating Unit of Histones and DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Chemical approaches for studying histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitination of histone H2B by Rad6 is required for efficient Dot1-mediated methylation of histone H3 lysine 79.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Gene silencing: trans-histone regulatory pathway in chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

The language of covalent histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Histone H4-K16 acetylation controls chromatin structure and protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitination of histone H2B regulates chromatin dynamics by enhancing nucleosome stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

H2B ubiquitylation plays a role in nucleosome dynamics during transcription elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitination of PCNA and its essential role in eukaryotic translesion synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Role of post-translational modifications in modulating the structure, function and toxicity of alpha-synuclein: implications for Parkinson's disease pathogenesis and therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitination of alpha-synuclein by Siah-1 promotes alpha-synuclein aggregation and apoptotic cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitination of alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Semisynthetic, site-specific ubiquitin modification of α-synuclein reveals differential effects on aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Will the ubiquitin system furnish as many drug targets as protein kinases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Targeting deubiquitinases enabled by chemical synthesis of proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

What Determines the Specificity and Outcomes of Ubiquitin Signaling?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

Generation of a Mono-ubiquitinated PCNA Mimic by Click Chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201200020

21 January 2018

Identifiers

DOI

10.1002/ANIE.201200020

1 reference

27 August 2017

1 reference