Beta-amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease (Q38034089)

27 August 2017

title

Beta-amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease (English)

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27 August 2017

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Flora Marianna Tomasello

2

object named as

Flora Tomasello

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27 August 2017

Maria Laura Giuffrida

object named as

Maria Laura Giuffrida

1

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Ferdinando Nicoletti

object named as

Ferdinando Nicoletti

5

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author name string

Filippo Caraci

3

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27 August 2017

Santina Chiechio

4

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27 August 2017

Agata Copani

6

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27 August 2017

publication date

12 August 2012

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27 August 2017

published in

Molecular Neurobiology

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27 August 2017

volume

46

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27 August 2017

issue

3

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27 August 2017

page(s)

605-613

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https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

27 August 2017

1 reference

Resolving controversies on the path to Alzheimer's therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

IGF-I and the aging mammalian brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Contributions of brain insulin resistance and deficiency in amyloid-related neurodegeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Neurodegenerative disorders associated with diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Correlating cerebral hypometabolism with future memory decline in subsequent converters to amnestic pre-mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Insulin receptors and insulin action in the brain: review and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Developmental regulation of insulin in the mammalian central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Insulin and neurodegenerative disease: shared and specific mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Intracerebroventricular insulin enhances memory in a passive-avoidance task.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Role of insulin and insulin receptor in learning and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Hypothalamic GLUT 4 expression: a glucose- and insulin-sensing mechanism?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Glucose transporter expression in the central nervous system: relationship to synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Critical nodes in signalling pathways: insights into insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Signaling by insulin-like growth factor 1 in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: comparison with insulin-like growth factors I and II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Insulin-like growth factor 1 regulates developing brain glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Insulin-like growth factor I modifies electrophysiological properties of rat brain stem neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Sedentary life impairs self-reparative processes in the brain: the role of serum insulin-like growth factor-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Role of insulin-like growth factor I signaling in neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Neuronal activity drives localized blood-brain-barrier transport of serum insulin-like growth factor-I into the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

The insulin-like growth factor system and its pleiotropic functions in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease – is this type 3 diabetes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

The brain insulin signal transduction system and sporadic (type II) Alzheimer disease: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Role for neuronal insulin resistance in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

A common pathogenic mechanism linking type-2 diabetes and Alzheimer's disease: evidence from animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Alzheimer's disease: molecular genetics and transgenic animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Diabetes mellitus and the risk of dementia: The Rotterdam Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Gene expression profile in streptozotocin rat model for sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Abeta-degrading enzymes: modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Nature of the amyloid-beta monomer and the monomer-oligomer equilibrium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Structural and kinetic features of amyloid beta-protein fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

The cell cycle molecules behind neurodegeneration in Alzheimer's disease: perspectives for drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Amyloid beta protein enhances the survival of hippocampal neurons in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

BACE1 (beta-secretase) transgenic and knockout mice: identification of neurochemical deficits and behavioral changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

BACE1 knock-outs display deficits in activity-dependent potentiation of synaptic transmission at mossy fiber to CA3 synapses in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

APP processing and synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and -insoluble pools in CHO-695 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Serum insulin-like growth factor I regulates brain amyloid-beta levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Beta-amyloid monomers are neuroprotective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Beta-catenin: a key mediator of Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Tau phosphorylation by GSK-3beta promotes tangle-like filament morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8313-6

Amyloid beta oligomers induce impairment of neuronal insulin receptors

21 January 2018

1 reference

12 December 2020

The production of amyloid beta peptide is a critical requirement for the viability of central neurons.

1 reference

12 December 2020

Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus.

1 reference

12 December 2020

In VivoAssessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life

1 reference

12 December 2020

Toward a comprehensive neurobiology of IGF-I.

1 reference

12 December 2020

Metabolic reserve as a determinant of cognitive aging

1 reference

12 December 2020

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

1 reference

12 December 2020

Peripheral cholesterol, metabolic disorders and Alzheimer's disease

1 reference

12 December 2020

The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses

1 reference

12 December 2020

Insulin-sensitive GLUT4 glucose transporters are colocalized with GLUT3-expressing cells and demonstrate a chemically distinct neuron-specific localization in rat brain

1 reference

12 December 2020

Four-day hyperinsulinemia in euglycemic conditions alters local cerebral glucose utilization in specific brain nuclei of freely moving rats

1 reference

12 December 2020

Oligomeric intermediates in amyloid formation: structure determination and mechanisms of toxicity

1 reference

12 December 2020

Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling.

1 reference

12 December 2020

Therapeutic targets of brain insulin resistance in sporadic Alzheimer's disease

1 reference

12 December 2020

Effects of insulin on local cerebral glucose utilization in the rat

1 reference

12 December 2020

Prognostic factors in paediatric anaplastic large cell lymphoma: role of ALK.

1 reference

12 December 2020

10.1007/S12035-012-8313-6

Identifiers

DOI

1 reference

Dimensions Publication ID

27 August 2017

1002109982

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1 reference