The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond (Q38041423)

27 August 2017

title

The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond (English)

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27 August 2017

Giovanni Monaco

1

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27 August 2017

Tim Vervliet

series ordinal

2

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27 August 2017

Haidar Akl

series ordinal

3

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27 August 2017

Geert Bultynck

series ordinal

4

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27 August 2017

publication date

6 September 2012

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Cellular and Molecular Life Sciences

27 August 2017

published in

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27 August 2017

volume

70

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27 August 2017

issue

7

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27 August 2017

page(s)

1171-1183

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How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

27 August 2017

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Ca(2+) transfer from the ER to mitochondria: when, how and why

21 January 2018

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PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

21 January 2018

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The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action

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A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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IP(3) Receptors, Mitochondria, and Ca Signaling: Implications for Aging

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy

21 January 2018

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Reduced loading of intracellular Ca(2+) stores and downregulation of capacitative Ca(2+) influx in Bcl-2-overexpressing cells.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Bcl-X(L) affects Ca(2+) homeostasis by altering expression of inositol 1,4,5-trisphosphate receptors

21 January 2018

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Modulation of endoplasmic reticulum calcium pump by Bcl-2.

21 January 2018

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Evidence for a role of the sarcoplasmic/endoplasmic reticulum Ca(2+)-ATPase in thapsigargin and Bcl-2 induced changes in Xenopus laevis oocyte maturation

21 January 2018

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Praf2 is a novel Bcl-xL/Bcl-2 interacting protein with the ability to modulate survival of cancer cells

21 January 2018

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Anti-apoptotic protein Bcl-2 interacts with and destabilizes the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA).

21 January 2018

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Displacement of SERCA from SR lipid caveolae-related domains by Bcl-2: a possible mechanism for SERCA inactivation

21 January 2018

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Heat-shock proteins attenuate SERCA inactivation by the anti-apoptotic protein Bcl-2: possible implications for the ER Ca2+-mediated apoptosis

21 January 2018

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Bcl-2 suppresses sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression in cystic fibrosis airways: role in oxidant-mediated cell death

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating

21 January 2018

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Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

21 January 2018

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Targeting Bcl-2 based on the interaction of its BH4 domain with the inositol 1,4,5-trisphosphate receptor.

21 January 2018

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Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction

21 January 2018

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21 January 2018

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Gastrulation in zebrafish -- all just about adhesion?

21 January 2018

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21 January 2018

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21 January 2018

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Calcium and the damage pathways in muscular dystrophy

21 January 2018

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21 January 2018

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Calcium homeostasis in vascular smooth muscle cells is altered in type 2 diabetes by Bcl-2 protein modulation of InsP3R calcium release channels

21 January 2018

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The Bcl-2 gene polymorphism rs956572AA increases inositol 1,4,5-trisphosphate receptor-mediated endoplasmic reticulum calcium release in subjects with bipolar disorder

21 January 2018

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Bcl-2 SNP rs956572 associates with disrupted intracellular calcium homeostasis in bipolar I disorder

21 January 2018

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Bcl-2 polymorphism influences gray matter volume in the ventral striatum in healthy humans

21 January 2018

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The mesolimbic dopamine reward circuit in depression

21 January 2018

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Initial testing (stage 1) of the BH3 mimetic ABT-263 by the pediatric preclinical testing program

21 January 2018

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Bcl-2 inhibitors: small molecules with a big impact on cancer therapy

21 January 2018

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Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy.

21 January 2018

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The Bcl-2 homology domain 3 mimetic ABT-737 targets the apoptotic machinery in acute lymphoblastic leukemia resulting in synergistic in vitro and in vivo interactions with established drugs

21 January 2018

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The Bcl-2 inhibitor ABT-263 enhances the response of multiple chemotherapeutic regimens in hematologic tumors in vivo

21 January 2018

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BCL2/BCL-X(L) inhibition induces apoptosis, disrupts cellular calcium homeostasis, and prevents platelet activation

21 January 2018

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Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

21 January 2018

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Programmed anuclear cell death delimits platelet life span.

21 January 2018

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Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis

21 January 2018

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BCL-2 and BCL-XL restrict lineage choice during hematopoietic differentiation

21 January 2018

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Molecular basis of the interaction between the antiapoptotic Bcl-2 family proteins and the proapoptotic protein ASPP2

21 January 2018

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BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

21 January 2018

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The voltage-dependent anion channel (VDAC): function in intracellular signalling, cell life and cell death.

21 January 2018

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VDAC, a multi-functional mitochondrial protein regulating cell life and death

21 January 2018

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The voltage-dependent anion channel-1 modulates apoptotic cell death.

21 January 2018

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The expression level of the voltage-dependent anion channel controls life and death of the cell

21 January 2018

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Bcl-x(L) blocks a mitochondrial inner membrane channel and prevents Ca2+ overload-mediated cell death

21 January 2018

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Oligomerization of the Mitochondrial Protein Voltage-Dependent Anion Channel Is Coupled to the Induction of Apoptosis

21 January 2018

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Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1: mapping the site of binding.

21 January 2018

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The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins.

21 January 2018

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Structure-based analysis of VDAC1: N-terminus location, translocation, channel gating and association with anti-apoptotic proteins.

21 January 2018

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NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL.

21 January 2018

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Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast

21 January 2018

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BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress

21 January 2018

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Cardiolipin, phosphatidylserine, and BH4 domain of Bcl-2 family regulate Ca2+/H+ antiporter activity of human Bax inhibitor-1.

21 January 2018

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BI-1 protects cells from oxygen glucose deprivation by reducing the calcium content of the endoplasmic reticulum

21 January 2018

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The ancient cell death suppressor BAX inhibitor-1.

21 January 2018

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Human Golgi antiapoptotic protein modulates intracellular calcium fluxes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1118-Y

TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1118-Y

ASPP: a new family of oncogenes and tumour suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1118-Y

ASPP2: a gene that controls life and death in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1118-Y

The ASPP interaction network: electrostatic differentiation between pro- and anti-apoptotic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1118-Y

New insights into the expanding complexity of the tumor suppressor ASPP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1118-Y

Insight into the structural basis of pro- and antiapoptotic p53 modulation by ASPP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1118-Y

A model for the interaction between NF-kappa-B and ASPP2 suggests an I-kappa-B-like binding mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1118-Y

The structure and interactions of the proline-rich domain of ASPP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1118-Y

Insights into the structure and protein-protein interactions of the pro-apoptotic protein ASPP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1118-Y

DeathBase: a database on structure, evolution and function of proteins involved in apoptosis and other forms of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1118-Y

Ca(2+) signaling mechanisms of cell survival and cell death: an introduction

21 January 2018

1 reference

12 December 2020

Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production

1 reference

12 December 2020

Endoplasmic reticulum/mitochondria calcium cross-talk.

1 reference

12 December 2020

Mitochondrial calcium signalling: message of life and death

1 reference

12 December 2020

Regulation of autophagy by the inositol trisphosphate receptor

1 reference

12 December 2020

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

1 reference

12 December 2020

Suppression of IP3-mediated calcium release and apoptosis by Bcl-2 involves the participation of protein phosphatase 1

1 reference

12 December 2020

10.1007/S00018-012-1118-Y

Identifiers

DOI

1 reference

27 August 2017

1 reference