LRRK2 and autophagy: a common pathway for disease. (Q38044446)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22988880%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

LRRK2 and autophagy: a common pathway for disease (English)

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13 February 2020

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1

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13 February 2020

author name string

Claudia Manzoni

series ordinal

1

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27 August 2017

language of work or name

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1 October 2012

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22988880%20AND%20SRC:MED&resulttype=core&format=json

Biochemical Society Transactions

13 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22988880%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

40

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13 February 2020

page(s)

1147-1151

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13 February 2020

issue

5

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Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

13 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

The function of ROCO proteins in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Receptor-interacting protein (RIP) kinase family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Roc, a Ras/GTPase domain in complex proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Genetic factors influencing age at onset in LRRK2-linked Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Identification of the autophosphorylation sites of LRRK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

On the road to leucine-rich repeat kinase 2 signalling: evidence from cellular and in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

LRRK2 in Parkinson's disease: biochemical functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

LRRK2 regulates synaptic vesicle endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

LRRK2 function on actin and microtubule dynamics in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

LRRK2 inhibition attenuates microglial inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

LRRK2 is involved in the IFN-gamma response and host response to pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

MAPK-pathway activity, Lrrk2 G2019S, and Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Leucine-rich repeat kinase 2 associates with lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Membrane localization of LRRK2 is associated with increased formation of the highly active LRRK2 dimer and changes in its phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Biochemical and pathological characterization of Lrrk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Clinical and pathological characteristics of patients with leucine-rich repeat kinase-2 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Regulation of physiologic actions of LRRK2: focus on autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

The emerging role of autophagy in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Autophagy deregulation in neurodegenerative diseases - recent advances and future perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Rapamycin alleviates toxicity of different aggregate-prone proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

VPS35 mutations in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

The leucine rich repeat kinase 2 (LRRK2) G2019S substitution mutation. Association with Parkinson disease, malignant melanoma and prevalence in ethnic groups in Israel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Genomewide association study of leprosy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

LRRK2 and human disease: a complicated question or a question of complexes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

Functional consequences of mutations in the autophagy genes in the pathogenesis of Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

TB: screening for responses to a vile visitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120126

21 January 2018

Identifiers

DOI

10.1042/BST20120126

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22988880%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference