The long non-coding RNAs, a new cancer diagnostic and therapeutic gold mine (Q38045210)

27 August 2017

The long non-coding RNAs, a new cancer diagnostic and therapeutic gold mine (English)

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27 August 2017

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Peng Qi

1

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PubMed ID

22996375

27 August 2017

Xiang Du

series ordinal

2

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27 August 2017

21 September 2012

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27 August 2017

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27 August 2017

26

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27 August 2017

2

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27 August 2017

155-165

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https://scigraph.springernature.com/pub.10.1038/modpathol.2012.160

27 August 2017

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MicroRNAs: target recognition and regulatory functions

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Regulation of mRNA translation and stability by microRNAs

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Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells

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Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

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MicroRNAs: novel regulators in the hallmarks of human cancer

21 January 2018

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MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer

21 January 2018

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MicroRNA expression profiles classify human cancers

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Molecular classification of solid tumours: towards pathway-driven therapeutics

21 January 2018

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The genetic signatures of noncoding RNAs

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Long non-coding RNAs: insights into functions

21 January 2018

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Expression of neural BC200 RNA in human tumours.

21 January 2018

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BC200 RNA in invasive and preinvasive breast cancer

21 January 2018

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Long noncoding RNAs and human disease

21 January 2018

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Decoding the function of nuclear long non-coding RNAs

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Genome regulation by long noncoding RNAs.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Transcription control by long non-coding RNAs

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Large non-coding RNAs: missing links in cancer?

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Relaxation of imprinted genes in human cancer.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Long noncoding RNA as modular scaffold of histone modification complexes

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Polycomb group protein-mediated repression of transcription

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Roles of the EZH2 histone methyltransferase in cancer epigenetics

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Genome-wide identification of polycomb-associated RNAs by RIP-seq

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Antisense transcription in the mammalian transcriptome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

The regulation of INK4/ARF in cancer and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

A transcriptional sketch of a primary human breast cancer by 454 deep sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Phenotypic characterization of endometrial stromal sarcoma of the uterus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Prognostic significance of drug-regulated genes in high-grade osteosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Cloning of an Alpha-TFEB fusion in renal tumors harboring the t(6;11)(p21;q13) chromosome translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Upregulation of the transcription factor TFEB in t(6;11)(p21;q13)-positive renal cell carcinomas due to promoter substitution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

MALAT-1 enhances cell motility of lung adenocarcinoma cells by influencing the expression of motility-related genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Inhibition of metastasis-associated lung adenocarcinoma transcript 1 in CaSki human cervical cancer cells suppresses cell proliferation and invasion

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

The H19 locus: role of an imprinted non-coding RNA in growth and development.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

H19 expression in hepatic metastases from a range of human carcinomas

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

The H19 non-coding RNA is essential for human tumor growth

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Association of IGF2 and H19 imprinting with choriocarcinoma development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

H19 mRNA-like noncoding RNA promotes breast cancer cell proliferation through positive control by E2F1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

RNA maps reveal new RNA classes and a possible function for pervasive transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Post-transcriptional processing generates a diversity of 5'-modified long and short RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

The imprinted H19 noncoding RNA is a primary microRNA precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Regulation and expression of a growth arrest-specific gene (gas5) during growth, differentiation, and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Cycling to cancer with cyclin D1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

CpG methylation analysis of the MEG3 and SNRPN imprinted genes in acute myeloid leukemia and myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Promoter hypermethylation of the MEG3 (DLK1/MEG3) imprinted gene in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Selective loss of MEG3 expression and intergenic differentially methylated region hypermethylation in the MEG3/DLK1 locus in human clinically nonfunctioning pituitary adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Subtle variations in Pten dose determine cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

The steroid receptor RNA activator protein is expressed in breast tumor tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Increasing the relative expression of endogenous non-coding Steroid Receptor RNA Activator (SRA) in human breast cancer cells using modified oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Accumulation of miR-155 and BIC RNA in human B cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Recurrent focal copy-number changes and loss of heterozygosity implicate two noncoding RNAs and one tumor suppressor gene at chromosome 3q13.31 in osteosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

LSINCT5 is over expressed in breast and ovarian cancer and affects cellular proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Large intervening non-coding RNA HOTAIR is associated with hepatocellular carcinoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Cell-free nucleic acids as biomarkers in cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Serum microRNAs as a novel class of biomarkers: a comprehensive review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Serum microRNAs as biomarkers for hepatocellular carcinoma in Chinese patients with chronic hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

DD3PCA3 RNA analysis in urine--a new perspective for detecting prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

DD3(PCA3)-based molecular urine analysis for the diagnosis of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Impact of cellular miRNAs on circulating miRNA biomarker signatures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Flow cytometric analysis of circulating microparticles in plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Exosomes as intercellular signalosomes and pharmacological effectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Non-coding RNAs and new opportunities for the private sector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Long noncoding RNA in genome regulation: prospects and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Long intergenic noncoding RNAs: new links in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Epigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in health

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Knocking down barriers: advances in siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

Delivery of siRNA therapeutics: barriers and carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

The widespread regulation of microRNA biogenesis, function and decay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

7 January 2021

Long Noncoding RNAs: Insights from Biological Features and Functions to Diseases.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

7 January 2021

Mechanisms of polycomb gene silencing: knowns and unknowns

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

7 January 2021

DNA sequence of the translocation breakpoints in undifferentiated embryonal sarcoma arising in mesenchymal hamartoma of the liver harboring the t(11;19)(q11;q13.4) translocation

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

7 January 2021

Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

7 January 2021

Steroid receptor RNA activator (SRA1): unusual bifaceted gene products with suspected relevance to breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

7 January 2021

SRA and its binding partners: an expanding role for RNA-binding coregulators in nuclear receptor-mediated gene regulation

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

7 January 2021

Prostate cancer: diagnostic performance of the PCA3 urine test

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.160

7 January 2021

10.1038/MODPATHOL.2012.160

Identifiers

DOI

1 reference

PubMed ID

22996375

Dimensions Publication ID

27 August 2017

0 references

1 reference

PubMed ID

22996375