Endoplasmic reticulum dysfunction in neurological disease (Q38067205)

28 August 2017

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title

Endoplasmic reticulum dysfunction in neurological disease (English)

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28 August 2017

endoplasmic reticulum

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author

Elena Miranda

series ordinal

3

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28 August 2017

6

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28 August 2017

4

Damian C Crowther

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28 August 2017

Benoit D Roussel

1

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ORCID Public Data File 2021

author name string

Antonina J Kruppa

series ordinal

2

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PubMed ID

23237905

28 August 2017

David A Lomas

series ordinal

5

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28 August 2017

1 January 2013

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28 August 2017

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28 August 2017

12

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28 August 2017

1

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28 August 2017

105-118

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Endoplasmic reticulum stress plays critical role in brain damage after cerebral ischemia/reperfusion in rats

28 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Induction of the unfolded protein response and cell death pathway in Alzheimer's disease, but not in aged Tg2576 mice

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Protein disulfide isomerase-immunopositive inclusions in patients with Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Expression of mutant or cytosolic PrP in transgenic mice and cells is not associated with endoplasmic reticulum stress or proteasome dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Proteasomal dysfunction and endoplasmic reticulum stress enhance trafficking of prion protein aggregates through the secretory pathway and increase accumulation of pathologic prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Reduced translocation of nascent prion protein during ER stress contributes to neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Heightened stress response in primary fibroblasts expressing mutant eIF2B genes from CACH/VWM leukodystrophy patients

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Overloaded endoplasmic reticulum-Golgi compartments, a possible pathomechanism of peripheral neuropathies caused by mutations of the peripheral myelin protein PMP22.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Interferon-gamma inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco-Sjögren syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

ER stress is involved in Abeta-induced GSK-3beta activation and tau phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Activation of PERK signaling attenuates Abeta-mediated ER stress

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

E2-25K/Hip-2 regulates caspase-12 in ER stress-mediated Abeta neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Presenilin-1 holoprotein is an interacting partner of sarco endoplasmic reticulum calcium-ATPase and confers resistance to endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Endoplasmic reticulum Ca(2+) handling in excitable cells in health and disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Protective effect against Parkinson's disease-related insults through the activation of XBP1

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Changes in endoplasmic reticulum stress proteins and aldolase A in cells exposed to dopamine

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Endoplasmic reticulum stress inducers provide protection against 6-hydroxydopamine-induced cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Changes in BiP availability reveal hypersensitivity to acute endoplasmic reticulum stress in cells expressing mutant huntingtin

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Global changes to the ubiquitin system in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Mechanism of ER stress-induced brain damage by IP(3) receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Endoplasmic reticulum stress in motor neurons of the spinal cord in sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Increased ER stress during motor neuron degeneration in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The unfolded protein response in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Involvement of IRE1α signaling in the hippocampus in patients with mesial temporal lobe epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Ca2+ homeostasis modulation enhances the amenability of L444P glucosylcerebrosidase to proteostasis regulation in patient-derived fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Apolipoprotein E-deficient mice are more vulnerable to ER stress after transient forebrain ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Involvement of endoplasmic reticulum stress in the neuronal death induced by transient forebrain ischemia in gerbil.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Characterization of neuronal and astroglial responses to ER stress in the hippocampal CA1 area in mice following transient forebrain ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

A molecular chaperone inducer protects neurons from ER stress

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Eif-2a protects brainstem motoneurons in a murine model of sleep apnea

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Valproate reduces CHOP levels and preserves oligodendrocytes and axons after spinal cord injury.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Endoplasmic reticulum stress signaling in disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

PERK is responsible for the increased phosphorylation of eIF2alpha and the severe inhibition of protein synthesis after transient global brain ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Phosphoproteins in stress-induced disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Transcriptional and translational control in the Mammalian unfolded protein response

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Homocysteine induces X-box-binding protein 1 splicing in the mice brain

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

ERAD: the long road to destruction

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

A time-dependent phase shift in the mammalian unfolded protein response

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Prolonged bihemispheric alterations in unfolded protein response related gene expression after experimental stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Involvement of endoplasmic reticulum stress after middle cerebral artery occlusion in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

HMG CoA reductase inhibitors reduce ischemic brain injury of Wistar rats through decreasing oxidative stress on neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Calcium, ischemia and excitotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Depletion of intracellular calcium stores is toxic to SH-SY5Y neuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Irreversible aggregation of protein synthesis machinery after focal brain ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Changes in the phosphorylation of initiation factor eIF-2alpha, elongation factor eEF-2 and p70 S6 kinase after transient focal cerebral ischaemia in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Edaravone protects against hypoxia/ischemia-induced endoplasmic reticulum dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Activation of caspase-12 by endoplasmic reticulum stress induced by transient middle cerebral artery occlusion in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Spread of an inactive form of caspase-12 in humans is due to recent positive selection

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Dysfunction of the unfolded protein response during global brain ischemia and reperfusion.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Increased vulnerability of hippocampal pyramidal neurons to the toxicity of kainic acid in OASIS-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

CHOP plays a pivotal role in the astrocyte death induced by oxygen and glucose deprivation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

GADD34 protein levels increase after transient ischemia in the cortex but not in the CA1 subfield: implications for post-ischemic recovery of protein synthesis in ischemia-resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Evolution of GADD34 expression after focal cerebral ischaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

ORP150 protects against hypoxia/ischemia-induced neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The unfolded protein response is activated in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The unfolded protein response affects neuronal cell cycle protein expression: implications for Alzheimer's disease pathogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

beta-Amyloid and endoplasmic reticulum stress responses in primary neurons: effects of drugs that interact with the cytoskeleton.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Abeta(1-42) and aluminum induce stress in the endoplasmic reticulum in rabbit hippocampus, involving nuclear translocation of gadd 153 and NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

NF-kappaB activated by ER calcium release inhibits Abeta-mediated expression of CHOP protein: enhancement by AD-linked mutant presenilin 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The ER stress factor XBP1s prevents amyloid-beta neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Altered localization of amyloid precursor protein under endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

A novel polymorphism in SEL1L confers susceptibility to Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Proteomic insights into the protective mechanisms of an in vitro oxidative stress model of early stage Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The endoplasmic reticulum stress sensor, ATF6α, protects against neurotoxin-induced dopaminergic neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The homocysteine-inducible endoplasmic reticulum stress protein counteracts calcium store depletion and induction of CCAAT enhancer-binding protein homologous protein in a neurotoxin model of Parkinson disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Activation of the unfolded protein response in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Rrs1 is involved in endoplasmic reticulum stress response in Huntington disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Derlin-1 overexpression ameliorates mutant SOD1-induced endoplasmic reticulum stress by reducing mutant SOD1 accumulation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Familial dementia caused by polymerization of mutant neuroserpin

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The ER-overload response: activation of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Dantrolene is neuroprotective in Huntington's disease transgenic mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

ER stress response plays an important role in aggregation of α-synuclein

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

Quinotrierixin inhibited ER stress-induced XBP1 mRNA splicing through inhibition of protein synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2812%2970238-7

7 January 2021

10.1016/S1474-4422(12)70238-7

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23237905