Is specific HIV eradication from the brain possible or needed? (Q38071699)

28 August 2017

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title

Is specific HIV eradication from the brain possible or needed? (English)

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28 August 2017

3

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28 August 2017

Lachlan Gray

2

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Bruce J Brew

object named as

Bruce J Brew

series ordinal

1

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author name string

Melissa Churchill

series ordinal

4

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PubMed ID

23289898

28 August 2017

language of work or name

English

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publication date

5 January 2013

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Expert Opinion on Biological Therapy

28 August 2017

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28 August 2017

13

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28 August 2017

3

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28 August 2017

403-409

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Towards an HIV cure: a global scientific strategy

28 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

HIV cure and eradication: how will we get from the laboratory to effective clinical trials?

21 January 2018

1 reference

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Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

HIV reservoirs: pathogenesis and obstacles to viral eradication and cure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

HIV reservoirs and strategies for eradication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

HIV-1 DNA is detected in bone marrow populations containing CD4+ T cells but is not found in purified CD34+ hematopoietic progenitor cells in most patients on antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Hematopoietic precursor cells isolated from patients on long-term suppressive HIV therapy did not contain HIV-1 DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Highlights from the 2012 International Symposium on HIV & Emerging Infectious Diseases (ISHEID): from cART management to the search of an HIV cure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Polyamides reveal a role for repression in latency within resting T cells of HIV-infected donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

CpG methylation controls reactivation of HIV from latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Epigenetic regulation of HIV-1 latency by cytosine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Transcriptional interference antagonizes proviral gene expression to promote HIV latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Regulation of HIV-1 latency by T-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Induction of HIV-1 replication in latently infected CD4+ T cells using a combination of cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Quantitative 3D video microscopy of HIV transfer across T cell virological synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

21 January 2018

HDAC inhibitors in HIV.

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Eradication of HIV by transplantation of CCR5-deficient hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Relationship of antiretroviral treatment to postmortem brain tissue viral load in human immunodeficiency virus-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Immune activation of the central nervous system is still present after >4 years of effective highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Prevalence of non-confounded HIV-associated neurocognitive impairment in the context of plasma HIV RNA suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Genetically modified CD34+ hematopoietic stem cells contribute to turnover of brain perivascular macrophages in long-term repopulated primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

The neuropathogenesis of AIDS

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2013.748029

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Cells of the central nervous system as targets and reservoirs of the human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Human polyomavirus JC reactivation and pathogenetic mechanisms of progressive multifocal leukoencephalopathy and cancer in the era of monoclonal antibody therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Biomarkers of HIV related central nervous system disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Neuroimaging in the brain in HIV-1-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Neuroimaging studies of the aging HIV-1-infected brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Updated research nosology for HIV-associated neurocognitive disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Lessons from the AN 1792 Alzheimer vaccine: lest we forget.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

Brain cell reservoirs of latent virus in presymptomatic HIV-infected individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.748029

10.1517/14712598.2013.748029

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23289898