Regulation of TNF-α with a focus on rheumatoid arthritis (Q38102876)

28 August 2017

Regulation of TNF-α with a focus on rheumatoid arthritis (English)

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28 August 2017

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Jo Van Damme

3

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Paul Proost

object named as

Paul Proost

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4

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author name string

Eva A V Moelants

series ordinal

1

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PubMed ID

23628802

28 August 2017

Anneleen Mortier

series ordinal

2

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28 August 2017

30 April 2013

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Immunology & Cell Biology

28 August 2017

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28 August 2017

91

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28 August 2017

6

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28 August 2017

393-401

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Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment

28 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Evidence that cytokines play a role in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Immunological therapies for rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: all alleles are important

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Pathogenesis of bone erosions in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Cytokines in the pathogenesis of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Rheumatoid synovial endothelial cells produce macrophage colony-stimulating factor leading to osteoclastogenesis in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Receptor activator NF-kappaB ligand (RANKL) expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathy, osteoarthritis, and from normal patients: semiquantitative and quantitative analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Inhibition of osteoblast differentiation by tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Chemokines and their receptors in rheumatoid arthritis: future targets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Infectious complications of biologic treatments of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

An endotoxin-induced serum factor that causes necrosis of tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Transcriptional control of the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

The role of the AU-rich elements of mRNAs in controlling translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Regulation of cytokines by small RNAs during skin inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

miRNA-125b regulates TNF-α production in CD14+ neonatal monocytes via post-transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Switching from repression to activation: microRNAs can up-regulate translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Involvement of microRNA in AU-rich element-mediated mRNA instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Signalling pathways of the TNF superfamily: a double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Cloning and partial characterization of the promoter for the human p55 tumor necrosis factor (TNF) receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Human tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Hydrogen peroxide enhances shedding of type I soluble tumor necrosis factor receptor from pulmonary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Nitric oxide enhances expression and shedding of tumor necrosis factor receptor I (p55) in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

TNF receptor 2 pathway: drug target for autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Chemokine and cytokine processing by matrix metalloproteinases and its effect on leukocyte migration and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Role of interleukin 1 and interleukin 1 receptor antagonist in the mediation of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Citrullination of TNF-α by peptidylarginine deiminases reduces its capacity to stimulate the production of inflammatory chemokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Crystallization and preliminary X-ray analysis of the tumour necrosis factor alpha-tumour necrosis factor receptor type 2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Solution of the structure of the TNF-TNFR2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

TNF-mediated inflammatory disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Tumor necrosis factor receptor cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Regulated commitment of TNF receptor signaling: a molecular switch for death or activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Prevention of constitutive TNF receptor 1 signaling by silencer of death domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

TRAF2 is essential for TNF-alpha-induced osteoclastogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

The essential role of MEKK3 in TNF-induced NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

The IKK complex: an integrator of all signals that activate NF-kappaB?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

IL-6 and NF-IL6 in acute-phase response and viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

MEK kinase 3 directly activates MKK6 and MKK7, specific activators of the p38 and c-Jun NH2-terminal kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

From JNK to pay dirt: jun kinases, their biochemistry, physiology and clinical importance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Death receptors: signaling and modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

NF-kappaB signals induce the expression of c-FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Signal transduction by tumor necrosis factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Etk/Bmx transactivates vascular endothelial growth factor 2 and recruits phosphatidylinositol 3-kinase to mediate the tumor necrosis factor-induced angiogenic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Role of cytokines in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

The role of Natural Killer cells in the pathogenesis of rheumatoid arthritis: major contributors or essential homeostatic modulators?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Involvement of interleukin 1 and tumour necrosis factor alpha as endogenous growth factors in human osteoblastic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Seeing the wood for the trees: the forgotten role of neutrophils in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Dynamics of early synovial cytokine expression in rodent collagen-induced arthritis : a therapeutic study using a macrophage-deactivating compound.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Endothelial-leukocyte adhesion molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Detection of interleukin 8 biological activity in synovial fluids from patients with rheumatoid arthritis and production of interleukin 8 mRNA by isolated synovial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Recombinant human TNF induces production of granulocyte-monocyte colony-stimulating factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Purification and characterization of human fibroblast-derived hybridoma growth factor identical to T-cell-derived B-cell stimulatory factor-2 (interleukin-6).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Dendritic cells in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Calcium signaling in osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Regulation of osteoclast differentiation and function by the CaMK-CREB pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Tumor necrosis factor alpha (TNF-alpha)-induced prostaglandin E2 release is mediated by the activation of cyclooxygenase-2 (COX-2) transcription via NFkappaB in human gingival fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Lipopolysaccharide-stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

TRAF5 functions in both RANKL- and TNFalpha-induced osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Predicting the future of anti-tumor necrosis factor therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

A multicenter, double-blind, dose-ranging, randomized, placebo-controlled study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis: radiologic progression and correlation of Genant and Larsen scores

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Efficacy and safety of the human anti-IL-1β monoclonal antibody canakinumab in rheumatoid arthritis: results of a 12-week, Phase II, dose-finding study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Denosumab: RANKL inhibition in the management of bone loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

Chemokine blockade and chronic inflammatory disease: proof of concept in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

CC chemokine receptor small molecule antagonists in the treatment of rheumatoid arthritis and other diseases: a current view

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

CCR5 (chemokine receptor-5) DNA-polymorphism influences the severity of rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

CCR5 blockade in rheumatoid arthritis: a randomised, double-blind, placebo-controlled clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Constitutive mRNA and protein production of macrophage colony-stimulating factor but not of other cytokines by synovial fibroblasts from rheumatoid arthritis and osteoarthritis patients

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Interplay between different epigenetic modifications and mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Association between rheumatoid arthritis and polymorphism of tumor necrosis factor receptor II, but not tumor necrosis factor receptor I, in Caucasians

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Tumor necrosis factor: function, release and clearance.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Chemokine secretion of rheumatoid arthritis synovial fibroblasts stimulated by Toll-like receptor 2 ligands

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: critical role of myeloid differentiation factor 88

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Dynamics of proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis (CIA)

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

The chemotactic activity for granulocytes produced by virally infected fibroblasts is identical to monocyte-derived interleukin 8

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Leukotriene B4 stimulates human polymorphonuclear leukocytes to synthesize and release interleukin-8 in vitro

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Angiogenesis in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Dickkopf-1 is a master regulator of joint remodeling

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Selective accumulation of CCR5+ T lymphocytes into inflamed joints of rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.15

7 January 2021

Identifiers

DOI

10.1038/ICB.2013.15

1 reference

28 August 2017

1 reference

PubMed ID

23628802