Protein lysine acetylation guards metabolic homeostasis to fight against cancer (Q38105878)

28 August 2017

title

Protein lysine acetylation guards metabolic homeostasis to fight against cancer (English)

1 reference

28 August 2017

W Xu

1

1 reference

28 August 2017

Y Li

series ordinal

2

1 reference

28 August 2017

C Liu

series ordinal

3

1 reference

28 August 2017

S Zhao

series ordinal

4

1 reference

28 August 2017

language of work or name

English

0 references

publication date

13 May 2013

1 reference

28 August 2017

1 reference

28 August 2017

volume

33

1 reference

28 August 2017

issue

18

1 reference

28 August 2017

page(s)

2279-2285

1 reference

On the Origin of Cancer Cells

28 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Glycolysis, glutaminolysis and cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

p53 and metabolism: old player in a new game

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Regulatory role of p53 in cancer metabolism via SCO2 and TIGAR in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

RNA synthesis and histone acetylation during the course of gene activation in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Histone acetylation and transcriptional regulatory mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Histone acetylation and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

CREBBP mutations in relapsed acute lymphoblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Conjunction dysfunction: CBP/p300 in human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

The impact of acetylation and deacetylation on the p53 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Acetylation is indispensable for p53 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Regulation of RAS oncogenicity by acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Atmospheric carbon dioxide concentrations over the past 60 million years

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Transcriptional regulation of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Alpha-keto acid dehydrogenase complexes. X. Regulation of the activity of the pyruvate dehydrogenase complex from beef kidney mitochondria by phosphorylation and dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Regulation of cellular metabolism by protein lysine acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Lysine acetylation targets protein complexes and co-regulates major cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Acetylation negatively regulates glycogen phosphorylase by recruiting protein phosphatase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Calorie restriction alters mitochondrial protein acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Acetylation of mitochondrial proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Mitochondrial protein acetylation regulates metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Acetylation of histones and transcription-related factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Regulation of intracellular levels of NAD: a novel role for CD38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Linking histone acetylation to transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Carbon catabolite repression in bacteria: many ways to make the most out of nutrients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

The CRE1 carbon catabolite repressor of the fungus Trichoderma reesei: a master regulator of carbon assimilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Intracellular 2-keto-3-deoxy-6-phosphogluconate is the signal for carbon catabolite repression of phenylacetic acid metabolism in Pseudomonas putida KT2440.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Mitochondrial metabolism of reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

The mitochondrial pyruvate dehydrogenase complex: nucleotide and deduced amino-acid sequences of a cDNA encoding the Arabidopsis thaliana E1 α-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Pyruvate kinase M2 is a phosphotyrosine-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Mitochondrial sirtuins in the regulation of mitochondrial activity and metabolic adaptation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Inherited susceptibility to uterine leiomyomas and renal cell cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Mutations in SDHC cause autosomal dominant paraganglioma, type 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Succinate dehydrogenase (SDH) D subunit (SDHD) inactivation in a growth-hormone-producing pituitary tumor: a new association for SDH?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

IDH1 and IDH2 mutations in gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

IDH1 mutant structures reveal a mechanism of dominant inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

α-Enolase: a promising therapeutic and diagnostic tumor target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Histone deacetylase inhibitors in cancer therapy: latest developments, trends and medicinal chemistry perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Roles of histone acetyltransferases and deacetylases in gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

HIF, a missing link between metabolism and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

The logic linking protein acetylation and metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Catalytic mechanism and function of invariant glutamic acid 173 from the histone acetyltransferase GCN5 transcriptional coactivator

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

PTEN, energy metabolism and tumor suppression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

Glycogen phosphorylase: control by phosphorylation and allosteric effectors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.163

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ONC.2013.163

1 reference

Dimensions Publication ID

28 August 2017

1050718920

0 references

Fatcat ID

release_ey5rlcrngzhblnsvccah4hlcqe

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ey5rlcrngzhblnsvccah4hlcqe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference