The NLRP3 inflammasome in Alzheimer's disease (Q38107892)

29 August 2017

The NLRP3 inflammasome in Alzheimer's disease (English)

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29 August 2017

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2

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29 August 2017

5

Lan Tan

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29 August 2017

3

Teng Jiang

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29 August 2017

Meng-Shan Tan

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PubMed ID

23686772

29 August 2017

Xi-Chen Zhu

series ordinal

4

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29 August 2017

19 May 2013

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29 August 2017

Molecular Neurobiology

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29 August 2017

48

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29 August 2017

3

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29 August 2017

875-882

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https://scigraph.springernature.com/pub.10.1007/s12035-013-8475-x

29 August 2017

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cites work

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Pattern recognition receptors and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Caspase-1 inflammasomes in infection and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Inflammasomes: guardians of cytosolic sanctity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Evolution and functional divergence of NLRP genes in mammalian reproductive systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Intracellular NOD-like receptors in host defense and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Non-canonical inflammasome activation targets caspase-11

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Manipulation of host cell death pathways during microbial infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Emerging inflammasome effector mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Apoptosis: controlled demolition at the cellular level

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Deregulated inflammasome signaling in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

A role for mitochondria in NLRP3 inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Critical role for calcium mobilization in activation of the NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Mechanisms of regulated unconventional protein secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Inflammasomes and their roles in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Neuroimmunomodulation in the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

The role of neuroimmunomodulation in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Interleukin-1 mediates Alzheimer and Lewy body pathologies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Pro-inflammatory cytokines and their effects in the dentate gyrus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Proinflammatory cytokines and apoptosis following glutamate-induced excitotoxicity mediated by p38 MAPK in the hippocampus of neonatal rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Role and mechanisms of interleukin-1 in the modulation of neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Interleukin-1beta but not tumor necrosis factor-alpha potentiates neuronal damage by quinolinic acid: protection by an adenosine A2A receptor antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Distribution of interleukin-1 receptor complex at the synaptic membrane driven by interleukin-1β and NMDA stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Mechanisms underlying inflammation in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Modulation of inflammasome pathways by bacterial and viral pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Inflammasome inhibition as a pathogenic stealth mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

COPs and POPs: modulators of inflammasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Innate immunity in Alzheimer's disease: a complex affair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8475-X

Evidence that increased hippocampal expression of the cytokine interleukin-1 beta is a common trigger for age- and stress-induced impairments in long-term potentiation.

21 January 2018

1 reference

12 December 2020

Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases

1 reference

12 December 2020

Interleukin-1 beta activates expression of cyclooxygenase-2 and inducible nitric oxide synthase in primary hippocampal neuronal culture: platelet-activating factor as a preferential mediator of cyclooxygenase-2 expression

1 reference

12 December 2020

Antimalarial drug artemisinin extenuates amyloidogenesis and neuroinflammation in APPswe/PS1dE9 transgenic mice via inhibition of nuclear factor-κB and NLRP3 inflammasome activation

1 reference

12 December 2020

10.1007/S12035-013-8475-X

Identifiers

DOI

1 reference

PubMed ID

23686772

Dimensions Publication ID

29 August 2017

0 references

1 reference

PubMed ID

23686772